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501. AHRQ Has Special Emphasis Notice on Grants About Innovative Methods Research To Increase the Utility of Systematic Reviews | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/news/grants-innovative-methods
     August 01, 2018 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

502. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
     January 01, 2015 - We graded the evidence separately for the RCTs and the observational studies.17 The final evidence grade … and conclusion were typically based on the RCT grade and could be strengthened by evidence from the … We classified evidence pertaining to the Key Questions into four categories: (1) high grade (indicating … For heart rate, only two comparisons had sufficient data to grade the evidence as more than insufficient … Only two comparisons had sufficient data to grade the evidence as more than insufficient or low.

503. Migraine-Emergency Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/migraine-emergency_executive.pdf
     November 01, 2012 - body of evidence using the EPC Grading of Recommendations Assessment, Development, and Evaluation (GRADE … For KQ 3, we did not grade outcomes because there were no comparative effectiveness analyses.

504. Disposition of Comments Report for Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/vte-prophyalaxis_disposition-comments.pdf
     May 29, 2013 - Disposition of Comments Report for Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations Comparative Effectiveness Research Review Disposition of Comments Report Research Review Title: Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special P…

505. Evidence-based Practice Center Systematic Review Protocol: Management of High-Need, High-Cost Patients: A Realist and Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/mgmt-hnhc-patients-protocol.pdf
     November 07, 2019 - Systematic Review: Grading the Strength of Evidence For KQ 3, we will grade the strength of evidence … (SOE) based on the guidance established for the EPC Program.42 Developed to grade the overall strength … Definitions of the grades of overall strength of evidence42 Grade Definition High High confidence that

506. Interventions for the Prevention of Post-traumatic Stress Disorder in Adults After Exposure to Psychological Trauma | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/ptsd-adults-trauma-interventions/research-protocol
     December 01, 2019 - Grading the Evidence for Each Key Question We will grade the strength of evidence based on the guidance … established for the Evidence-based Practice Center Program. 47 Developed to grade the overall strength … We will grade the strength of evidence for the outcomes deemed to be of greatest importance to decisionmakers … Definitions of the grades of overall strength of evidence 47 Grade Definition High

507. Treatments for Seasonal Allergic Rhinitis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/allergy-seasonal/research-protocol
     December 01, 2020 - evidence will be based on the Evidence-based Practice Center (EPC) approach, which is similar to the GRADE … treatment comparison of interest, the body of evidence will be evaluated separately to derive a single GRADE … The GRADE definitions are as follows: High : high confidence that the evidence reflects the true … symptom that is hard to tolerate; causes interference with activities of daily living and/or sleeping) GRADE

508. Primary Care Management of Abnormal Uterine Bleeding (AUB) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/abnormal-uterine-bleeding/research-protocol
     December 01, 2020 - Studies will be given a quality grade of good, fair, or poor per the established criteria for the assessment … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Two senior staff will independently grade the body of evidence with disagreements resolved through discussion

509. Effectiveness of Treatments for Diabetic Peripheral Neuropathy | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/diabetic-neuropathy/research-protocol
     April 01, 2020 - Major Comparisons and Outcomes At the completion of our review, two reviewers will independently grade … Major Comparisons and Outcomes At the completion of our review, two reviewers will independently grade

510. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
     August 07, 2012 - Grading the Evidence for Each Key Question - We will grade the overall strength of the body of evidence … Two reviewers will assess each domain and the overall grade for each key outcome listed in the PICOTS … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that

511. Disposition of Comments Report for Childhood Obesity Prevention Programs: A Comparative Effectiveness Review and Meta-Analysis (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/obesity-child_disposition-comments.pdf
     June 10, 2013 - weight- related outcomes together with each study contributing only one weight- related measure to the grade … The summary strength of evidence tables provide details about how we arrived at each grade. … the grading of evidence follows the recommendation in the AHRQ Methods guide which is based on the GRADE … consider both the quantity of literature and the quality of the literature when we assign an evidence grade … in the Executive Summary and in the main report: “We caution that a “high” strength of evidence grade

512. Abnormal-Uterine-Bleeding Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
     November 21, 2011 - Studies will be given a quality grade of good, fair, or poor per the established criteria for the … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Two senior staff will independently grade the body of evidence with disagreements resolved through

513. Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/angina-heart-attack-treatments/research-protocol
     December 01, 2019 - The strength of evidence will also be assigned an overall grade of high, moderate, low, or insufficient

514. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
     March 11, 2010 - Introduction DCIS classifications use histologic grade, so the statement that only invasive tumors are … described by histologic grade is inaccurate.

515. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
     July 18, 2011 - safety (e.g., sedation, dizziness, restless legs/akathisia, anxiety, and vomiting) outcomes using the Grade … For each key outcome for each comparison, we will assign an overall evidence grade based on the ratings

516. Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
     March 19, 2018 - Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma Draft review availa…

517. Ptsd-Adults-Trauma-Interventions Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
     November 08, 2012 - We will grade the strength of evidence based on the guidance established for the Evidence-based Practice … Center Program.47 Developed to grade the overall strength of a body of evidence, this approach incorporates … We will grade the strength of evidence for the outcomes deemed to be of greatest importance to decision … Definitions of the grades of overall strength of evidence47 Grade Definition High High confidence

518. Pneumonia-Antibiotic-Treatment Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
     November 01, 2014 - graded the strength of evidence based on the guidance established for the EPC program.23 Developed to grade … The overall grade was based on a qualitative decision taking into account the ratings for the four required

519. Effectiveness of Treatments for Diabetic Peripheral Neuropathy (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
     May 09, 2016 - Major Comparisons and Outcomes: At the completion of our review, two reviewers will independently grade … Major Comparisons and Outcomes At the completion of our review, two reviewers will independently grade

520. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
     December 11, 2012 - The strength of evidence will also be assigned an overall grade of high, moderate, low, or insufficient