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261. heart-failure-readmission-protocol-130611 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_research-protocol.pdf
     June 10, 2013 - Grading the Strength of Evidence for Individual Comparisons and Outcomes We will grade the strength … based on the guidance established for the Evidence- based Practice Center (EPC) Program.47 Developed to grade … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that … Source: Owens et al., 201047 We will grade the strength of evidence for all outcomes related to … We will not grade the evidence for KQ 3; this question is a descriptive question. G.

262. Alcohol-misuse-drug-therapy-140326 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
     January 27, 2012 - Grading the Strength of Evidence (SOE) for Individual Comparisons and Outcomes—We will grade the strength … based on the guidance established for the Evidence-based Practice Center Program.45 Developed to grade … We will grade the strength of evidence for alcohol-consumption measures, accidents, injuries, quality … Definitions of the grades of overall strength of evidence45 Grade Definition High High confidence

263. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - Abdul-Aziz and colleagues26 did not appraise the quality of individual studies or grade the quality … Grading the Strength of Evidence (SOE) for Individual Comparisons and Outcomes We will grade the … on the guidance established for the Evidence- based Practice Center (EPC) Program.33 Developed to grade … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that … Source: Owens et al.33 We will grade the strength of evidence for the outcomes deemed to be of greatest

264. Topic 0502 Non-Muscle Invasive Bladder Cancer NSD FINAL_SJ (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND-0587-131115.pdf
     March 06, 2013 - How do tumor characteristics (stage, grade, multiplicity, size, molecular and genetic alterations)

265. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/disparities-quality-improvement_research-protocol.pdf
     February 23, 2012 - Studies will be given a quality grade of good, fair, or poor per the Methods Guide for Effectiveness … www.effectivehealthcare.ahrq.gov Published Online: February 23, 2012 12 interest will be given an overall evidence grade … Two senior staff will independently grade the body of evidence; disagreements will be resolved as needed

266. Comparative Effectiveness of Noninvasive Technologies for the Diagnosis of Coronary Artery Disease (CAD) in Women | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/cad-women-diagnosis/research-protocol
     December 01, 2019 - The strength of evidence will also be assigned an overall grade of high, moderate, low, or insufficient

267. Systematic Review of Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
     January 01, 2020 - Grading the Strength of Evidence (SOE) for Major Compar isons and Outcomes We will grade the strength … Developed to grade the overall strength of a body of evidence, this approach now incorporates five key … We will grade the strength of evidence for all included outcomes. … Definitions of the Grades of Overall Strength of Evidence Grade Definition High We are very confident

268. Systematic Review of Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/breastfeeding/research-protocol
     October 01, 2019 - Grading the Strength of Evidence (SOE) for Major Comparisons and Outcomes We will grade the strength … Developed to grade the overall strength of a body of evidence, this approach now incorporates five key … We will grade the strength of evidence for all included outcomes. Table 3. … Definitions of the Grades of Overall Strength of Evidence Grade Definition Source:

269. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system is widely … of a Body of Evidence That Includes NRSIs The AHRQ EPC Program adopted a modified version of the GRADE … to the lack of randomization and higher potential for confounding.97 Thus, an initial provisional grade … Grade strength of evidence for NRSIs using established guidance. … GRADE guidelines: 3. Rating the quality of evidence.

270. Methods Guide for Comparative Effectiveness Reviews_Inclusion of Nonrandomized Studies of Interventions in Systematic Reviews of Intervention Effectiveness: An Update (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
     September 01, 2022 - The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system is widely … of a Body of Evidence That Includes NRSIs The AHRQ EPC Program adopted a modified version of the GRADE … to the lack of randomization and higher potential for confounding.97 Thus, an initial provisional grade … Grade strength of evidence for NRSIs using established guidance. … GRADE guidelines: 3. Rating the quality of evidence.

271. Nitrous Oxide for the Management of Labor Pain | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/labor-nitrous-oxide/research-protocol
     December 01, 2019 - Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Two senior staff will independently grade the body of evidence, with disagreements resolved through discussion

272. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
     October 01, 2011 - evidence for each Key Question using the four categories recommended in the AHRQ guide:19 A “high” grade … further research is very unlikely to change our confidence in the estimate of effect; a “moderate” grade … A recent large, good-quality NIH-funded trial found the combination of pharmaceutical grade glucosamine … product (no pharmaceutical-grade glucosamine available in the United States). 13 Table A. … • Most trials showing therapeutic benefits from glucosamine were conducted using pharmaceutical-grade

273. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/colorectal-cancer-liver-metastases-therapies_research-protocol.pdf
     September 27, 2012 - the EPC staff believes that such evidence could impact results meaningfully (i.e., alter evidence GRADE … 27, 2012 evidence is outlined in the Methods Guide25 and is based on a system developed by the GRADE … The grade of evidence strength is classified into the following four categories: • High. … The grade rating will be made by independent reviewers, and disagreements will be resolved by consensus

274. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/depression-chronic-conditions-interventions_research-protocol.pdf
     September 21, 2011 - Grading the Evidence for Each Key Question – We will grade the strength of evidence based on the guidance … established for the Evidence-based Practice Center (EPC) Program. 35 Developed to grade the overall … Definitions of the grades of overall strength of evidence Grade Definition High High confidence that … Source: Owens et al., 201035 We will grade the strength of evidence for the outcomes deemed to be of

275. Title (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/obesity-child_research-protocol.pdf
     March 31, 2010 - Grading the Evidence for Each Key Question At the completion of the review, we will grade the quantity … We will classify evidence pertaining to Key Questions 1- 7 into four basic categories: (1) “high” grade … research is very unlikely to change our confidence in the estimate of the effect); (2) “moderate” grade … research may change our confidence in the estimate of the effect and may change the estimate); (3) “low” grade … confidence in the estimate of the effect and is likely to change the estimate); and (4) “insufficient” grade

276. Dietary Intake of Polyunsaturated Fatty Acids and Plasma Lipid and Cardiovascular Events | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/polyunsaturated-fatty/protocol
     November 01, 2024 - low-quality evidence per the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE … GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. … for Healthcare Research and Quality DRI Dietary reference intake EPC Evidence-based Practice Center GRADE

277. CER 174 Executive Summary: Imaging for the Pretreatment of Small Cell Lung Cancer (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/lung-cancer-staging_executive.pdf
     April 01, 2016 - The output is a grade for the strength of evidence: high, moderate, low, or insufficient. … This grade is provided separately for each outcome of each comparison of each KQ. … A grade was determined separately for each modality comparison (e.g., CT vs. PET/CT). … If the evidence was sufficient to permit a conclusion, the grade was deemed high, moderate, or low. … The grade was provided by three independent raters, with discrepancies resolved by consensus.

278. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/depression-brain-injury_research-protocol.pdf
     December 09, 2009 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: December 9, 2009 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Traumatic Brain Injury and Depression I. Background and Objectives…

279. Comparative Effectiveness of Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/vte-prophyalaxis/research-protocol
     December 01, 2019 - Grading the Evidence for Each Key Question At the completion of our review, we will grade the quantity … We will classify evidence pertaining to KQs 1–8 into four basic categories: 1) “high” grade (indicating … further research is very unlikely to change our confidence in the estimate of the effect); 2) “moderate” grade … research may change our confidence in the estimate of the effect and may change the estimate); 3) “low” grade … confidence in the estimate of the effect and is likely to change the estimate); and 4) “insufficient” grade

280. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hepatitis-c_research-protocol.pdf
     November 30, 2011 - Key Question We will use the methods outlined in Chapter 10 of the AHRQ Methods Guide 18 to grade … Based on this assessment, the body of evidence will be assigned a strength-of-evidence grade of high … November 30, 2011 9 evidence does not exist, is sparse, or contains irreconcilable inconsistency, a grade