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1201. Arthritis and Nontraumatic Joint Disease (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-13121.pdf
      December 05, 2013 - hyaluronic acid treatments.70 In another trial, patients (n=120) with knee OA Kellgren and Lawrence grade … In a randomized, double-blind, controlled trial, patients (n=109) with knee OA Kellgren- Lawrence grade … The authors reported a “trend” for improvement in the PRP group patients with low-grade articular degeneration

1202. Alcohol-Misuse Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/alcohol-misuse_executive.pdf
      April 28, 2010 - Grade: B Recommendation (i.e., the USPSTF recommends that clinicians provide the service to eligible … Grade: I Statement (insufficient evidence to make a recommendation).

1203. Physical Therapy for Knee Pain Secondary to Osteoarthritis Disposition of Comment Report (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/arthritis-knee-physical-therapy_disposition-comments.pdf
      November 06, 2012 - We revised our definitions of precision, following the recently published GRADE recommendations. … We integrate GRADE 6 concept for precision. … We revised precision definitions following the recently published GRADE recommendations.

1204. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
      March 11, 2010 - Introduction DCIS classifications use histologic grade, so the statement that only invasive tumors are … described by histologic grade is inaccurate.

1205. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
      July 18, 2011 - safety (e.g., sedation, dizziness, restless legs/akathisia, anxiety, and vomiting) outcomes using the Grade … For each key outcome for each comparison, we will assign an overall evidence grade based on the ratings

1206. Technical Brief Disposition of Comments Report for Gene Expression Profiling for Predicting Outcomes in Stage II Colon Cancer (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/colon-cancer-gene-profiling_disposition-comments.pdf
      December 14, 2012 - failure to recognize that, if the same level of evidence standards were applied to existing markers (grade … Given what we know about traditional markers, particularly tumor grade, it is almost certain that patients

1207. Disposition of Comments for CER 152 Nonmetastatic Muscle-Invasive Bladder Cancer (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bladder-cancer-muscle-invasive_disposition-comments.pdf
      June 30, 2015 - Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology. … Genomic Predictors of Survival in Patients with High-grade Urothelial Carcinoma of the Bladder.

1208. Comparative Effectiveness of Preventive Pharmacological Treatments for Migraine | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/migraine-prevention/research-protocol
      December 01, 2019 - We will define evidence as insufficient when a single study with high Table 1 Grade

1209. Omega 3 Fatty Acids and Maternal and Child Health | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/omega-3-maternity/research-protocol
      January 01, 2020 - 3 fatty acid supplemented foods (e.g., eggs) with quantified n-3 content High-dose pharmaceutical grade … Summary of Evidence Reviewed Outcome Strength of Evidence Grade Study Design (number of

1210. Omega-3-Maternity Research-Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/omega-3-maternity_research-protocol.pdf
      May 18, 2015 - fatty acid supplemented foods (e.g., eggs) with quantified n-3 content § High-dose pharmaceutical grade … Summary of Evidence Reviewed Outcome Strength of Evidence Grade Study Design (number of studies

1211. CER 229 Evidence Summary: Opioid Treatments for Chronic Pain (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
      April 01, 2020 - CER 229 Evidence Summary: Opioid Treatments for Chronic Pain Purpose of Review To assess the effectiveness and harms of opioid therapy for chronic noncancer pain, alternative opioid dosing strategies, and risk mitigation strategies Key Messages • Opioids are associated with small improvements versus placebo in …

1212. Pharmacotherapy for Adults With Alcohol Use Disorder (AUD) in Outpatient Settings | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/alcohol-misuse-drug-therapy/clinician
      January 01, 2021 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

1213. Comparing Medical Interventions: AHRQ and the Effective Health Care Program | Effective Health Care (EHC) Program
      effectivehealthcare-admin.ahrq.gov/products/medical-interventions-comparing/methods
      December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

1214. Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
      March 19, 2018 - Disposition of Comments CER 194 Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Intermittent Inhaled Corticosteroids and Long-Acting Muscarinic Antagonists for Asthma Draft review availa…

1215. Disposition of Comments for CER 182 Glasgow Coma Scale (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/field-triage-glascow-disposition-170415.pdf
      January 12, 2017 - GRADE or some other methodology? … using the approach described in the AHRQ Methods Guide, which is similar to the methods used by GRADE … I am not an expert in search methodology but have participated in a number of GRADE methodology reviews

1216. Ptsd-Adults-Trauma-Interventions Research-Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ptsd-adults-trauma-interventions_research-protocol.pdf
      November 08, 2012 - We will grade the strength of evidence based on the guidance established for the Evidence-based Practice … Center Program.47 Developed to grade the overall strength of a body of evidence, this approach incorporates … We will grade the strength of evidence for the outcomes deemed to be of greatest importance to decision … Definitions of the grades of overall strength of evidence47 Grade Definition High High confidence

1217. Abnormal-Uterine-Bleeding Research-Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
      November 21, 2011 - Studies will be given a quality grade of good, fair, or poor per the established criteria for the … Each key outcome on each comparison of interest will be given an overall evidence grade based on the … Two senior staff will independently grade the body of evidence with disagreements resolved through

1218. Pneumonia-Antibiotic-Treatment Executive (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
      November 01, 2014 - graded the strength of evidence based on the guidance established for the EPC program.23 Developed to grade … The overall grade was based on a qualitative decision taking into account the ratings for the four required

1219. Effectiveness of Treatments for Diabetic Peripheral Neuropathy (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetic-neuropathy_research-protocol.pdf
      May 09, 2016 - Major Comparisons and Outcomes: At the completion of our review, two reviewers will independently grade … Major Comparisons and Outcomes At the completion of our review, two reviewers will independently grade

1220. Evidence-based Practice Center Systematic Review Protocol (pdf file)
      effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
      December 11, 2012 - The strength of evidence will also be assigned an overall grade of high, moderate, low, or insufficient