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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-decision-modeling.ppt
June 01, 2012 - always feasible due to:
Short time spans
Limited resources
Modeling requires:
Technical expertise
A good … Moreover, creating decision models requires technical expertise and a good appreciation of the clinical … The analytic framework used in the systematic review is a good starting point. … Using the analytical framework developed in the systematic review is a good starting point for achieving … Decision Modeling Step 4: Evaluate Previous Modeling Studies (2 of 3)
Once it is determined that good-quality
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - Studies will then be
given an overall score of good, fair, or poor. … Summary ratings of quality of individual studies
Quality Rating Definition
Good (low risk of bias) … Good studies have the least bias and results are considered valid. … Fair studies do not meet all the criteria required for a rating of good
quality because they have some
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-quantitative-synthesis_methods.pdf
October 01, 2010 - We consider it good practice to report the proportion of events from each intervention group in
addition … Investigators can choose to combine the large studies if they
are well conducted with good quality … The Bayesian fixed effects model provides good estimates when
events are rare for binary data.
38 … Good
knowledge of the clinical and biological background of the topic and key questions is important
-
effectivehealthcare.ahrq.gov/sites/default/files/methodsguide_conductingquantitativesynthesis.pdf
October 01, 2010 - We consider it good practice to report the proportion of events from each intervention group in
addition … Investigators can choose to combine the large studies if they
are well conducted with good quality … The Bayesian fixed effects model provides good estimates when
events are rare for binary data.
38 … Good
knowledge of the clinical and biological background of the topic and key questions is important
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
December 11, 2018 - Reviews.16 Based on the risk of bias assessment,
individual included studies will be rated as being “good … Studies rated “good” are considered to have the least risk of bias, and their results
are considered … Good-quality studies employ valid methods for selection,
inclusion, and allocation of patients to treatment … These studies may not meet all the criteria for a rating of good quality,
but no flaw is likely to cause
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
February 13, 2012 - These techniques are not used this way – for
good reason. … This report will do more harm than good. … Good science cannot
occur in a vacuum. … Therefore the patient population under
study does not contain a good representation of patients
thought
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
December 01, 2024 - Evidence size Few large trials
published
There are multiple large
good-quality trials. … Searching for unpublished negative trials might
be less impactful if several large good-quality
trials
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effectivehealthcare.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
May 14, 2020 - No response
needed
Quality of Report TEP Reviewer #2 Good Thank you. … No response
needed
Quality of Report Peer Reviewer #3 Good Thank you. … No response
needed
Quality of Report Peer Reviewer #4 Good Thank you.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-2-nonopioid-pharm-chronic-pain.pdf
April 01, 2022 - December 2021 yielded 81
citations, and identified five new eligible studies (in 6 publications): two good-quality6 … for Surveillance Report 2
Evidence Details
Key Question 1: Benefits
Neuropathic Pain
One new good-quality … One
good-quality RCT (n=306) found no differences in worst and average numerical rating scale
score … Key Question 2: Harms
Anticonvulsants
One good-quality RCT (n=306)6,7 and one fair-quality RCT (n … inverse agonist AZD5213 in
combination with pregabalin in patients with
painful diabetic neuropathy and good
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/omega-3-maternity_disposition-comments.pdf
October 12, 2016 - Peer Reviewer
#1
Quality of Report Good Thank you. … TEP Reviewer
#3
Quality of Report Good Thank you. … TEP Reviewer
#5
Introduction Good overview of the differences between the
chemical compounds being … The future research section is clear and provides
good direction for future studies.
Thank you. … The reviewer raises a good point.
-
effectivehealthcare.ahrq.gov/sites/default/files/palliative-care-tools-disposition.pdf
May 04, 2017 - ”
8 Peer Reviewer #2 Findings The key informant interviews add valuable perspective and
there is good … comment.
13 Peer Reviewer #2 Clarity and Usability The report is well structured and organized, with a good … There
is quite a difference between “none” and one, if that one
instrument is a good measurement tool … future research, but there are some
important inconsistencies and missing measures that would
be good … Seems like a good place for
a researcher to start on instrument development.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/palliative-care-tools-disposition.pdf
May 04, 2017 - ”
8 Peer Reviewer #2 Findings The key informant interviews add valuable perspective and
there is good … comment.
13 Peer Reviewer #2 Clarity and Usability The report is well structured and organized, with a good … There
is quite a difference between “none” and one, if that one
instrument is a good measurement tool … future research, but there are some
important inconsistencies and missing measures that would
be good … Seems like a good place for
a researcher to start on instrument development.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias-individual-studies_methods.pdf
March 01, 2012 - For example, studies that met the majority of
the items for all domains are good; studies that met the … It has demonstrated good face,
content, and concurrent validity and has been tested for reliability. … It has shown face, content, and construct
validity and good inter-rater reliability.12 The tool has … Case series • Do the reports have good predictive value?
• How was causality determined? … )
0: study does not meet above criteria
Total quality score = sum of
scores (0-8)
>6: Good
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - The obvious
assumption is that unless other specified, that you’re
talking about “good” outcomes, but … They do a good job with their
description of how bias was rated. … While I believe there was some good intent in
the purpose of this review of the literature, there were … not
motivated to adhere to an intervention for the
time period hypothesized to be necessary for
good … The
publication of this review in its current state may
cause more harm than good.
-
effectivehealthcare.ahrq.gov/sites/default/files/cognitive-decline-disposition-170707pdf.pdf
March 24, 2017 - The obvious
assumption is that unless other specified, that you’re
talking about “good” outcomes, but … They do a good job with their
description of how bias was rated. … While I believe there was some good intent in
the purpose of this review of the literature, there were … not
motivated to adhere to an intervention for the
time period hypothesized to be necessary for
good … The
publication of this review in its current state may
cause more harm than good.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_disposition-comments.pdf
September 29, 2014 - However, I only
ranked the quality as “good”. … Peer Reviewer
10
Clarity and
Usability
Good Thank you for your comment. … The dearth of good quality studies is even more alarming considering recent
estimates (2012) of opioid … Simply put, the extensive long-term use of opioids is not supported by good quality
studies concerning … Because there is not even good
evidence examining the effectiveness
and harms of long-term opioid use
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment_research-protocol.pdf
September 13, 2012 - both the RCTs and the nonrandomized
studies, the overall study quality will be assessed as:
• Good … They did not meet all the criteria required for a rating of good quality because
they had some deficiencies … include rash, intolerance,
allergy
MRSA Clindamycin Also can treat anaerobes; allergy is
rare; good … MRSA;
requires multiple daily dosing; GI intolerance
Trimethoprim/sulfamethoxazole Inexpensive; good
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
March 15, 2010 - Briefly, we will rate each study as being of good, fair, or
poor quality based on their adherence to … Therefore, randomized controlled trials will be graded good,
fair, or poor, and observational studies … will separately be graded good, fair, or poor.
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_5-user-guide-to-ocer_130129.pdf
January 01, 2012 - Therefore,
patients who are not in good general condition due
to severe target disease or comorbidities … information on health behaviors or
their surrogates are available in all or a subset of
patients, or a good … Good
research practices for comparative effectiveness
research: Approaches to mitigate bias and
confounding
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis_research-protocol.pdf
June 06, 2011 - the summary
judgment of the quality of the individual studies, we will use the summary ratings of
good … Randomized controlled trials will be graded as
good, fair, or poor. … Observational studies will graded separately, also as good, fair, or
poor.