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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0488_12-27-2011.pdf
    January 01, 2011 - Staff-Generated PICO Population(s): People (primarily adults) at high risk for pancreatic cancer (
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0351_05-10-2010.pdf
    January 01, 2010 - Staff-Generated PICO Population(s): patients with cryptorchidism (undescended testicle) Intervention
  3. TND-612-09-03-2013 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-612-09-03-2013.pdf
    January 01, 2013 - Staff-Generated PICO Population(s): Children with special health care needs (CSHCN) as defined by
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0745-141009.pdf
    September 03, 2014 - Staff-Generated PICO Population(s): Women with symptomatic uterine fibroids Intervention(s): Uterine
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0519_02-27-2012.pdf
    January 01, 2012 - Staff-Generated PICO Population(s): Patients with heart failure requiring hospitalization, including
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
    July 13, 2011 - Evidence Report on the Source: www.effectivehealthcare.ahrq.gov Published Online: July 13, 2011 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Second Generation Antidepressants in the Pharmacologic Treatment of Adult Depression – An Update to a 20…
  7. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/antidepressants-update_executive.pdf
    December 01, 2011 - Layout 1 Background Depressive disorders such as major depressive disorder (MDD), dysthymia, and subsyndromal depression (including minor depression) may be serious disabling illnesses. MDD is the most prevalent, affecting more than 16 percent (lifetime) of U.S. adults. In 2000, the U.S. economic burden of depressiv…
  8. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - Layout 1 Background Type 2 diabetes is characterized by insulin resistance accompanied by progressive deficiency in insulin secretion. Type 2 diabetes is an increasingly common disease that is closely associated with obesity. In 2005, the prevalence of Americans with diagnosed type 2 diabetes was 2.4 percent for ad…
  9. effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update Source: https://www.effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports/ ?pageaction=displayproduct&productid=2437 Published Online: March 16, 2017 Comparative Effectiveness Review Disposi…
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
    March 16, 2017 - First- and Second-Generation Antipsychotics in Children and Young Adults: Systematic Review Update Source: https://www.effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports/ ?pageaction=displayproduct&productid=2437 Published Online: March 16, 2017 Comparative Effectiveness Review Disposi…
  11. Ced -Appendix-2 (xls file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
    May 29, 2025 - Does the evidence generated in a study or series of studies allow CMS efficiently to end a CED with a … Does the evidence generated in a study or series of studies allow CMS efficiently to end a CED with a
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
    January 01, 2010 - Staff-Generated PICO Population(s): (1) Patients with acute coronary syndrome, (2) patients who have
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0652-131114.pdf
    May 15, 2013 - Staff-Generated PICO Population(s): Pregnant women Intervention(s): Strategies for the prevention and
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0255_06-25-2010.pdf
    January 01, 2010 - Staff-Generated PICO Population(s): 1) Patients evaluated with coronary catheterization for CAD
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0371_11-23-2010.pdf
    January 01, 2010 - Staff-Generated PICO Population(s): Persons aged 18 years or over who currently have, or at any time
  16. Ced-Appendix-3 (xls file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
    June 24, 2022 - captured in clinical records and would not lend themselves to being included in a RWE study unless patient-generated … requirements FDA Data Sponsors should select appropriate RWD sources based on their suitability to generated … NAM2019 Source Tag Recommendations NAM2019 Data Patient-generated data and community-led registries … requirements FDA Data_source Sponsors should select appropriate RWD sources based on their suitability to generated … ISPE_2020 Data_source Identify RWD sources that are “Fit for Purpose” NAM2019 Data_source Patient-generated
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0572-140408.pdf
    January 09, 2014 - Staff-Generated PICO Population(s): Adults with fecal incontinence, mostly women Intervention(s): Permanent
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0655-131114.pdf
    May 22, 2013 - Staff-Generated PICO Population(s): Children and adolescents with disruptive behavior disorders (DBDs
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0193_08-12-2009.pdf
    January 01, 2009 - Staff-Generated PICO Population(s): Patients requiring prescription medications for chronic conditions
  20. effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0373-14083.pdf
    July 09, 2014 - Staff-Generated PICO Population(s): Patients with SMI, with or without comorbid medical conditions such

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