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81. Disposition of Comments Report for Imaging Techniques for Treatment Evaluation for Metastatic Breast Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
    October 01, 2014 - Throughout the brief, we convey the importance of this information gap and describe some methods that … It seems this is a major gap in the evidence as noted page 19, line 4. … We agree this is a major gap in evidence and have described how this might be addressed in the Next … We agree, and have added language to allude to this knowledge gap at the end of the second paragraph … This is cited as a gap in evidence.

82. Obesity Prevention and Control (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/obesity-research-methods_research-protocol.pdf
    February 08, 2017 - Obesity Prevention and Control Obesity Prevention and Control Initial publication date if applicable: NA Amendment Date(s) if applicable: NA (Amendments Details–see Section VII) I. Background an…

83. Biomarkers for Assessing and Managing Iron Deficiency Anemia in Late-Stage Chronic Kidney Disease: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-kidney-disease-anemia_research.pdf
    January 01, 2013 - One major evidence gap concerns the dearth of pediatric studies. … Addressing this gap would require a specially-composed stakeholder group for determining specific Future … One major evidence gap concerns the dearth of pediatric studies (only one study enrolled pediatric HD … data substantially reduces resource use and increases the feasibility of addressing this evidence gap … should be no ethical issues in using an expert panel and horizon scan to investigate this evidence gap

84. FRN 30: Outpatient Case Management for Adults With Medical Illnesses and Complex Care Needs: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/case-management-future_research.pdf
    June 01, 2015 - importance, desirability of new research, feasibility, and potential impact while ranking each evidence gap … We informed them that we would contact them shortly with a list of research gap topics for their review … Stakeholders were asked to rate the priority of each gap for future research on a scale of 1 to 6, with … and ongoing studies, and potential study designs Domain Specific Top-Tier Topics Applicable PICOT Gap … studies, and potential study designs (continued) Domain Specific Top-Tier Topics Applicable PICOT Gap

85. CER 174 Executive Summary: Imaging for the Pretreatment of Small Cell Lung Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/lung-cancer-staging_executive.pdf
    April 01, 2016 - Each gap should be assigned one of the following reasons for the inability to draw conclusions: a. … This gap exists due to reason a, Insufficient information. … Thus, the reason for this gap is reason b, Information at risk of bias. … At least three underlying sources exist for the gap: (1) the general lack of direct comparisons of … The third gap concerns KQ3, which addressed the extent to which comparative accuracy or effectiveness

86. Bar-Cohen_ ECCS2012 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/bar-cohen_-eccs2012.pdf
    January 01, 2012 - asks provocative questions, keeps science grounded in solutions,  and  helps  bridge  the  gap

87. AHRQ’s EPC Program: Supporting Better Healthcare for 25 Years (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/25th-anniversary-epc-brochure.pdf
    November 01, 2022 - AHRQ’s EPC Program: Supporting Better Healthcare for 25 Years AHRQ’s Evidence-based Practice Center (EPC) Program has established a unique role in ongoing efforts to improve healthcare quality in America. The EPCs, housed at universities, medical centers, and research institutions, synthesize scientific evidence an…

88. Communicating Harms and Benefits of Prescription Drugs to Healthcare Consumers (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/communicating_risk_hickam.ppt
    December 01, 2006 - Communicating Harms and Benefits of Prescription Drugs to Healthcare Consumers Communicating Harms and Benefits of Prescription Drugs to Healthcare Consumers John M. Eisenberg Clinical Decisions and Communications Science Center Agency for Healthcare Research and Quality Effective Health Care Program The…

89. Future Research Needs for Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin II Receptor Antagonists (ARBs), or Direct Renin Inhibitors (DRIs) for Treating Hypertension (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-future_research.pdf
    March 01, 2012 - out of scope topics: • 356 articles identified • 32 included and linked to an out of scope research gap

90. Cer-265-Radiation-Bone-Disease-Addendum-App (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
    May 29, 2025 - ; MRI-confirmed asymptomatic metastases allowed; NRS pain ≥5; Epidural lesions with at least a 3-mm gap

91. Disposition of Comments Report for Evidence Report 215 Safety of Vaccines Used for Routine Immunization in the United States (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/vaccine-safety_disposition-comments.pdf
    January 01, 2020 - The research section is clear, however more specific examples of studies needed to fill the gap in … This is a statement of a conclusion rather than a description of a research gap.

92. Frameworks for Determining Research Gaps During Systematic Reviews | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/methods-future-research-steps-framework/research

93. Vaginal Birth After Cesarean: Developing and Prioritizing a Future Research Agenda (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth-future_research.pdf
    August 09, 2012 - Participants were asked both to (1) rate each evidence gap/research question as high, medium, or low

94. Disposition of Comments Report for Comparative Effectiveness Review No. 137 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-update_disposition-comments.pdf
    August 06, 2014 - Disposition of Comments Report for Comparative Effectiveness Review No. 137 Comparative Effectiveness Review Disposition of Comments Report Research Review Title: Therapies for Children With Autism Spectrum Disorder—Behavioral Interventions Update Draft review available for public comment from January…

95. Naik (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/naik.pdf
    January 01, 2009 - Naik Slide 1: Using  Electronic Health Records  to Better Coordinate Decision Making  for Complex Patients: What  CanWe Learn FromWiki? Aanand D. Naik, MD and Hardeep Singh, MD, MPH Houston HSR&D CoE, Michael E. DeBakey VA  Medical Center; Baylor College of Me…

96. Future Research Needs for the Comparative Effectiveness of Breathing Exercises and/or Retraining Techniques in the Treatment of Asthma (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-treatment-future_research.pdf
    September 01, 2012 - Respondents were asked to consider the potential impact, information gap, variation in research or clinical … these research questions would have been included in the original CER, thus, these indicate an evidence gap … Information Gap: More research on this topic is needed since it is not adequately answered by existing … these research questions would have been included in the original CER, thus, these indicate an evidence gap

97. Public-Reporting-Quality-Improvement Research-Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/public-reporting-quality-improvement_research-protocol.pdf
    August 17, 2011 - public reporting may influence quality of health care A review for the series Closing the Quality Gap … Background and Objectives for the Systematic Review Closing the Quality Gap: Revisiting the State … The CQG series aims to assemble the evidence about effective strategies to close the “quality gap”— … organizations are investing resources in public reporting as one possible intervention to bridge the gap … states that the “series aims to assemble the evidence about effective strategies to close the „quality gap

98. Disposition of Comments for Interventions To Improve Cardiovascular Risk Factors in People With Serious Mental Illness (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/mental-illness-heart_disposition-comments.pdf
    April 22, 2013 - associated with cognitive dulling and which also has been associated with hyperchloremic, non-anionic gap … Another specific gap is determining whether the weight-loss associated medications must be continued … We have modified one gap to include better reporting of adverse events and added an additional research

99. Pediatric Quality Measures Program 3.0: An Evidence Map of Measures for Vision, Hearing, and Developmental Screening and Followup (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/pqmp-protocol.pdf
    April 01, 2014 - Pediatric Quality Measures Program 3.0: An Evidence Map of Measures for Vision, Hearing, and Developmental Screening and Followup 1 1 Evidence-based Practice Center Technical Brief Protocol Project Title: Pediatric Quality Measures Program 3.0: An Evidence Map of Measures for Vision, Hearing, and Developm…

100. AHRQ Slide Template 2004 (ppt file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/introduction.ppt
     January 01, 2010 - AHRQ Slide Template 2004 The AHRQ Training Modules for the Systematic Reviews Methods Guide: An Introduction Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov The AHRQ Training Modules for Systematic Reviews Methods Guide: An Introd…