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61. Methods Future Research Needs Number 8: Framework for Considering Study Designs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/study-design-framework_research.pdf
    March 01, 2012 - Therefore, it may be difficult to know whether this proposed gap has already been filled. … Conversely, if an identified gap could be filled by RCTs, for example, but trials have been unable … why, for example, a cross-sectional study design is inappropriate as a means of filling an evidence gap … In assessing this topic, it was deemed that an important gap pertained to the comparative effectiveness … However, if the proposed evidence gap is conceptually quite far from the original key questions covered

62. Presentation of Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/presentations-future_research.pdf
    April 01, 2012 - Research in some areas may have sufficiently developed to the point where the gap can be precisely … issue, the FRN should address elements and level of detail and explain how this fills the evidence gap … An example of a methodological gap identified in an FRN relates to treatments for localized prostate … Research in some areas may have sufficiently developed to the point where the gap can be precisely

63. Evidence gaps for mHealth tools in diabetes | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/get-involved/nominated-topics/evidence-gaps-for-mhealth-tools-in-diabetes

64. Treatment for Restless Legs Syndrome: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/restless-legs-future_research.pdf
    February 01, 2013 - Stakeholder prioritization of research gap questions ................................................ … Research Gap Questions for Prioritization Appendix B. … Based upon these conversations, we refined and added to our initial list of research gap questions. … the natural breakpoints in these rankings, we determined high, moderate, and low priority research gap … Research Gap Questions Table 1.

65. Future Research Needs for Noncyclic Chronic Pelvic Pain Therapies for Women (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/pelvic-pain-therapies-future_research.pdf
    January 01, 2015 - Summary of steps for developing future research needs Approach to Evidence Gap Identification 1. … Research Quality (AHRQ) Future Research Needs Methods Report, Robinson et al.34 define a research gap … The report further notes that a research gap may not be a research need if filling the gap would not … Summary of steps for developing future research needs Approach to Evidence Gap Identification 1. … AHRQ published guidance,35 we describe key considerations and study design to address an evidence gap

66. Evidence-based Practice Center Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ongoing-studies-evidence_research.pdf
    December 01, 2010 - It is also important that caveats regarding the potential of ongoing studies to fill the research gap … posting of results (as is now required by law) and not automatically relied upon to fill a research gap … may help to determine the degree of reliance on a particular study to fill the identified research gap … The true potential these studies have to fill a particular research gap rests with the quality of the … relevant information sources and screening those results for relevance to an identified research gap

67. Treatment of Hepatitis C Virus Infection in Adults: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
    April 01, 2013 - Weights are based on the rank numbers (1–12) of each gap multiplied by how many stakeholders assigned … For the initial round, we weighted the scores based on how many stakeholders endorsed the gap multiplied … Initial prioritization of evidence gaps Research Gap Number of “High-Priority” Endorsements Number … Initial prioritization of evidence gaps (continued) Research Gap Number of “High-Priority” Endorsements … a Weights are based on the rank numbers (1-12) of each gap multiplied by how many stakeholders assigned

68. Transparency of Reporting Requirements: Strategies to Improve Mental Health Care for Children and Adolescents (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-mental-health_research-protocol.pdf
    September 01, 2016 - Given the gap between observed and achievable processes and outcomes, the next critical step is the … and the development of strategies to implement or disseminate these interventions.1-3 Closing the gap … Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies, Vol. 1: Series Overview

69. Future Research Needs for Childhood Obesity Prevention Programs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/child-obesity-future_research.pdf
    March 31, 2010 - Future Research Needs for Childhood Obesity Prevention Programs Future Research Needs Paper Number 31 Future Research Needs for Childhood Obesity Prevention Programs Future Research Needs Paper Number 31 Future Research Needs for Childhood Obesity Prevention Programs Identification of Future Resea…

70. Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/primary-research-design_research.pdf
    January 01, 2012 - Research White Paper: A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies   Research White Paper A Framework To Facilitate the Use of Systematic Reviews and Meta-analyses in the Design of Primary Research Studies …

71. Effective Health Care (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0193_08-12-2009.pdf
    January 01, 2009 - If little or no evidence exists, can new research be designed to address the gap? 4.

72. Evidence Report on the (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/patient-centered-medical-home_research-protocol.pdf
    February 23, 2012 - Evidence-based Practice Center Systematic Review Protocol Project Title: Closing the Quality Gap … As part of the Closing the Quality Gap series of Evidence- based Practice Center (EPC) reviews, the purpose … The key questions were refined via discussions with the EPC coordinating the “Closing the Quality Gap … Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies. … Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies.

73. Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/traumatic-brain-injury-rehabilitation-future_research.pdf
    January 01, 2013 - Stakeholder prioritization of research gap questions ................................................ … developed a Web-based survey using SurveyMonkey to collect stakeholder prioritization of the research gap … questions) Step 5: Revise preliminary research gap questions/consider ongoing research Step … Additional evidence gaps • Additional research questions • Additional ongoing research • Reduce gap … Stakeholder prioritization of research gap questions (continued) Question Ranking* Total (Points)

74. Disposition of Comments_Technical Brief 52: Pediatric Quality Measures Program 3.0: An Evidence Map of Measures for Vision, Hearing, and Developmental Screening and Followup (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/pqmp-disposition-comments.pdf
    April 07, 2025 - Affiliation Section Comment Response 3.2.4.2 and 3.3.4.5, description was provided on this evidence gap … This gap in care policies is a major oversight. … In sections 3.2.4.2 and 3.3.4.5, description was provided on this evidence gap related to measuring practice

75. FRN 41 - Noninvasive Technologies for the Diagnosis of Coronary Artery Disease in Women: Future Research Needs (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-diagnosis-future_research_1.pdf
    February 01, 2013 - characteristics to men are getting tested or development of a new observational study to explore this gap … Likelihood • Likelihood that the study would fill an identified evidence gap • Likelihood that the … study would fill an implementation gap (likely to improve translation of research findings or existing … the NITs Maybe: if RCT is not feasible, then an observational study could explore the evidence gap … characteristics to men are getting tested or development of a new observational study to explore this gap

76. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/health-careassociated-infections_research-protocol.pdf
    August 26, 2011 - 26, 2011 1 Evidence-based Practice Center Systematic Review Protocol Closing the Quality Gap … Successful strategies will help to close the quality gap regarding health care–associated infections … The first step in designing a quality improvement project is to identify a quality gap. … Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies. … Closing the Quality Gap: A Critical Analysis of Quality Improvement Strategies.

77. Future Research Needs: Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-interventions-future_research.pdf
    September 01, 2012 - Methods for developing future research needs Approach to Evidence Gap Identification 1. … Methods for developing future research needs Approach to Evidence Gap Identification 1.

78. Use of Observational Studies in Systematic Reviews of (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/methodsguidenorris_060420101.pdf
    June 01, 2010 - ideally were framed a priori in a review protocol, but rather a change in focus such that the (RCT) gap … Assess the risk of bias of observational studies to answer the gap review questions. … should proceed to assess the potential risk of bias in a body of observational studies used to answer gap

79. Use of Observational Studies in Systematic Reviews of (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-observational-studies_methods.pdf
    June 01, 2010 - ideally were framed a priori in a review protocol, but rather a change in focus such that the (RCT) gap … Assess the risk of bias of observational studies to answer the gap review questions. … should proceed to assess the potential risk of bias in a body of observational studies used to answer gap

80. FRN 22: Future Research Needs for Strategies To Reduce Cesarean Birth in Low-Risk Women (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cesarean-birth_research.pdf
    January 01, 2020 - Evidence gaps identified in the Comparative Effectiveness Review Evidence Gap Relevant PICOTS Elements … Evidence gaps identified in the Comparative Effectiveness Review Evidence Gap Relevant PICOTS Element … For example, the research gap “determinants of cesarean” appears early in the framework because it applies … anticipated that no more than nine non-Federal stakeholders would participate in each step of research gap … Prior to the call, we emailed each stakeholder the draft CER, slides describing the evidence gap identification