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401. Disposition of Comments for CER 160 Binge Eating Disorder (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/binge-eating-disposition-160504.pdf
     December 09, 2015 - This gap is especially critical for pharmacological treatments, as patients and their providers seek

402. Disposition of Comments for CER 166 Calcineurin Inhibitors (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/calcineurin-inhibitor_disposition-comments.pdf
     March 15, 2016 - limited data available on infections in studies of immunosuppression, and cited this as an important gap

403. Breastfeeding and Health Outcomes for Infants and Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/breastfeeding-health-outcomes-protocol.pdf
     February 01, 2023 - be used as a starting point for an update to the evidence, with additional searching to bridge the gap

404. S77 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s77.pdf
     October 01, 2007 - Cost-lowering strategies used by Medicare beneficiaries who exceed drug benefit caps and have a gap in

405. Topic Brief: Nonpharmacologic Treatment of Mental Health Conditions in Pregnant and Postpartum People (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/nt_docs/1002-nonpharmacologic-treatment-topic-brief.pdf
     June 03, 2024 - standard of care unclear (guidelines not available or guidelines inconsistent, indicating an information gap … practice variation (guideline inconsistent with current practice, indicating a potential implementation gap

406. Future Research Needs Document (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-risk-reduction_research.pdf
     October 25, 2010 - Future Research Needs Document Future Research Needs To Reduce the Risk of Primary Breast Cancer in Women was available for public comment from September 29, 2010, to October 25, 2010. In response to questions and suggestions received, revisions were made in this version to clarify that no incentives were offere…

407. antibiotics-respiratory-infection-protocol-140922 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_research-protocol.pdf
     September 22, 2014 - A 2006 technical review by AHRQ, entitled “Closing the Quality Gap: A Critical Analysis of Quality Improvement … In: Shojania KG MK, Wachter RM, Owens DK, ed Closing the Quality Gap: A Critical Analysis of Quality

408. Disposition of Comments Report for Imaging Tests for the Diagnosis and Staging of Pancreatic Adenocarcinoma (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_disposition-comments.pdf
     September 23, 2014 - their subsequent impacts on patient management, survival, or quality of life.”8 This is cited as a gap … However, we offer that this is not a gap, but rather includes some endpoints which are inappropriate

409. Methods Research Report: Improving Health Systems' Access to High-Quality Evidence: AHRQ EPC 2018 Pilot Projects Summary (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-report-improving-health-systems-access.pdf
     August 01, 2019 - positive feedback regarding these products suggests that they may be a useful step toward bridging the gap … Developing companion products may be one way the EPC program can attempt to close the gap between evidence … Mind the Gap: Putting Evidence into Practice in the Era of Learning Health Systems.

410. Disposition of Comments Report for CER 203 ADHD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-203-adhd-disposition-comments.pdf
     January 01, 2018 - one very well done review of behavior treatment that you should include and address to fill in the gap … It compares the three modalities for which you called in your summary of the treatment research gap … We hope that the field can act on this identified gap in the evidence. … review and in the current one put together, but that does not appear to be the case there is a 12 year gap

411. Disposition of Comments for Local Nonsurgical Therapies for Stage I and Symptomatic Obstructive Non-Small-Cell Lung Cancer (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/lung-cancer-nonsurgical-therapies_disposition-comments.pdf
     June 12, 2013 - The authors indentify a research gap in all key questions. 2.

412. Ptsd-Adults-Trauma-Interventions Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_executive.pdf
     April 01, 2013 - One key research gap for studies of targeted prevention is the limited ability to identify people who

413. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
     February 01, 2013 - Reviewers must rely on their expert judgment as to what constitutes a gap in the best possible evidence

414. Phenylketonuria Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/phenylketonuria_executive.pdf
     February 01, 2012 - 1 Comparative Effectiveness Review Number 56 Adjuvant Treatment for Phenylketonuria (PKU) Executive Summary Background Etiology Phenylketonuria (PKU) is a metabolic disorder in which an inability to properly metabolize the amino acid phenylalanine (Phe) leads to a buildup of Phe in the blood, causing neurot…

415. Disposition of Comments for Interventions for Adolescents and Young Adults With Autism Spectrum Disorders (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/autism-adolescents_disposition-comments.pdf
     August 27, 2012 - future motor and social communication functions of individuals with ASD is a significant research gap

416. Executive Summary: ADHD Diagnosis and Treatment in Children and Adolescents (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-267-adhd-executive-summary.pdf
     March 01, 2024 - Executive Summary: ADHD Diagnosis and Treatment in Children and Adolescents Comparative Effectiveness Review Number 267 ADHD Diagnosis and Treatment in Children and Adolescents Executive Summary Main Points Diagnosis • Multiple approaches showed promising diagnostic performance (e.g., usin…

417. Evidence-based Practice Center Systematic Review Protocol - Management of Infantile Epilepsies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-252-infantile-epilepsies-disposition-comments.pdf
     October 25, 2022 - people that are equally represented geographically and ethnically; shorten the clinical practice gap

418. Disposition of Comments: Technical Brief No. 39_Disparities and Barriers to Pediatric Cancer Survivorship Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-39-pediatric-cancer-survivorship-comments.pdf
     March 01, 2021 - Disposition of Comments: Technical Brief No. 39_Disparities and Barriers to Pediatric Cancer Survivorship Care Technical Brief Disposition of Comments Report Research Review Title: Disparities and Barriers to Pediatric Cancer Survivorship Care Draft report available for public comment from October 7, 2…

419. Disposition of Comments_Models of Care That Include Primary Care for Adult Survivors of Childhood Cancer: A Realist View (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/childhood-cancer-disposition-comments.pdf
     February 16, 2022 - The AHRQ fails to note this research gap, which is one of the main recommendations of the IOM report

420. Management of Acute Diverticulitis Topic Nomination Disposition (pdf file)
     effectivehealthcare.ahrq.gov/system/files/docs/acute-diverticulitis-topic-nomination.pdf
     August 13, 2018 - standard of care unclear (guidelines not available or guidelines inconsistent, indicating an information gap … practice variation (guideline inconsistent with current practice, indicating a potential implementation gap