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201. Disposition of Comments Report for Antiplatelet and Anticoagulant Treatments for Unstable Angina/Non-ST Elevation Myocardial Infarction (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/angina-heart-attack-treatments_disposition-comments.pdf
     January 01, 2014 - I think the knowing the optimal time prior of upstream administration is a research gap. … We have added this as a research gap. TEP Member 2 Results Overall, well done. … This is a research gap that needs to be addressed in future studies. … We agree that this is a research gap. … Peer Reviewer 4 Summary/ Discussion The research gap for KQ #1 isn’t stated clearly.

202. Heart-Failure-Transition-Care Clinician (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_clinician.pdf
     October 01, 2015 - Transitional Care Interventions To Prevent Readmissions for People With Heart Failure Focus of This Summary This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and harms of transitional care interventions (defined in Table 1) that aim to reduce readmiss…

203. Disposition of Comments for CER 183 Tonsillectomy for OSDB (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tonsillectomy-disposition-170415.pdf
     January 17, 2017 - Peer reviewer #4 Discussion An important research gap that was presented in the introduction and results

204. Alcohol-Misuse-Drug-Therapy Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/alcohol-misuse-drug-therapy_executive.pdf
     January 27, 2012 - Evidence gaps for future research by Key Question KQ Evidence Gap Potential Future Research 1 Evidence … Evidence gaps for future research by Key Question (continued) KQ Evidence Gap Potential Future Research

205. Disposition of Comments for Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Hospital-Acquired Pneumonia (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
     November 24, 2014 - Introduction Overall, the introduction is framed very well, and the authors effectively “frame the gap … TEP Reviewer #5 Discussion/ Conclusion In the “research gap” section (page 26), another point that

206. Pneumonia-Antibiotic-Treatment Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
     November 01, 2014 - The HCAP gap: differences between self-reported practice patterns and published guidelines for health

207. Disposition of Comments for Quality Improvement Interventions To Address Health Disparities (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_disposition-comments.pdf
     August 27, 2012 - Effectiveness Research Review Disposition of Comments Report Research Review Title: Closing the Quality Gap … Closing the Quality Gap: Revisiting the State of the Science Quality Improvement Interventions To Address … Whether those interventions are effective at closing the gap between two populations remains unclear … settings; it is possible that they could be adapted or targeted to narrow a health or health care gap … disparity population may mask the degree to which an intervention actually closes the disparities gap

208. serious-mental-illness-outcomes-140303 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-outcomes_research-protocol.pdf
     March 03, 2014 - serious-mental-illness-outcomes-140303 Evidence-based Practice Center Technical Brief Protocol Project Title: Outcomes of Serious Mental Illness I. Background and Obje…

209. Effective Health Care (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0095_04-10-2009.pdf
     January 01, 2009 - Effective Health Care Topic Number: 0142 Document Completion Date: 7-15-09 1 Results of Topic Selection Process & Next Steps  Noninvasive diagnosis of coronary artery disease in women will be developed as a systematic review by the Effective Health Care (EHC) Program.  When key questi…

210. Slide 1 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/introductory-slides-ahrq-cf-webinar.pdf
     August 27, 2012 - Slide 1 Community Forum Integrating Stakeholder Preferences in Comparative Effectiveness Research: Potential Uses of Multi-Criteria Decision Analysis Techniques August 27, 2012 Community Forum Community Forum Community Forum Vice President for Program Development, Center for Medical Technology Poli…

211. Chronic-Cough Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_executive.pdf
     March 01, 2014 - 1 Comparative Effectiveness Review Number 100 Assessment and Management of Chronic Cough Executive Summary Background In the United States, cough is the most common complaint for which patients seek medical attention and is the second most common reason for a general medical examination, accounting for …

212. Ced -Appendix-2 (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
     May 29, 2025 - flexibility to determine whether certain requirements may be waived based upon the technology, evidentiary gap … flexibility to determine whether certain requirements may be waived based upon the technology, evidentiary gap

213. Disposition of Comments Report for Prevention of Healthcare-Associated Infections (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/health-careassociated-infections_disposition-comments.pdf
     November 30, 2012 - Effectiveness Research Review Disposition of Comments Report Research Review Title: Closing the Quality Gap … Closing the Quality Gap: Revisiting the State of the Science. … duration of post- intervention assessment is specifically highlighted in the discussion as a knowledge gap

214. Environmental, Clinical and Economic Outcomes of Hospital Resources to Prevent Hospital-Acquired Infections (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/prevent-hai-protocol.pdf
     April 16, 2024 - Environmental, Clinical and Economic Outcomes of Hospital Resources to Prevent Hospital-Acquired Infections Evidence-based Practice Center Technical Brief Protocol Project Title: Environmental, Clinical and Economic Outcomes of Hospital Resources to Prevent Hospital-Acquired Infections I. Background and …

215. CER 215 Adverse Effects of Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-comments.pdf
     March 28, 2019 - In the Research Gap section on page 57, the investigators conclude that there were no data to evaluate

216. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
     December 31, 2022 - Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review Rapid Evidence Product Version 3.0 (July 2022) Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review What Di…

217. Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
     May 01, 2016 - Evidence Base The report identified several gaps and limitations in the evidence base: �� A critical gap

218. Introduction-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/introduction-user-guide-to-ocer_130129.pdf
     April 26, 2012 - 1 Introduction to Developing a Protocol for Observational Comparative Effectiveness Research: A User’s Guide Scott R. Smith, Ph.D. Agency for Healthcare Research and Quality, Rockville, MD Background When making health care decisions, patients, health care providers, and policymakers routinely seek unbiased inf…

219. Disposition of Comments for Technical Brief 35: Asthma Self-Management Education Packages (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-35-asthma-self-management-comments.pdf
     April 27, 2020 - organizations should consider: •Conducting a needs assessment to ensure the package fills a current gap

220. Disposition of Comments for Technical Brief 21, Management Strategies To Reduce Psychiatric Readmissions (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/psychiatric-readmissions_disposition-comments.pdf
     May 21, 2015 - Published Online: May 21, 2015 19 Commentator & Affiliation Section Comment Response “Fifth” gap … In terms of the optimal length of outpatient commitment, it may be more accurate to frame this as a gap … #5 Key Informant Summary and Implications p. 40 ff: In terms of gaps in the evidence base, one gap