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101. First Annual Report to Congress on High-Priority Evidence Gaps for Clinical Preventive Services - V | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/first-annual-report-congress-high-priority-evidence-gaps-clinical-preventive-services-v
     December 01, 2011 - hip fractures are less common in men than in women, more than one-third of men who experience a hip fracture … Randomized trials of primary clinical fracture prevention in men who have osteoporosis are needed.

102. Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/v7w4xaGG822hVc_SCU3tQ_
     November 01, 2022 - prevalence and incidence of most chronic diseases (eg, cardiovascular disease, cancer, osteoporosis, and fracture … prevalence and incidence of most chronic diseases (eg, cardiovascular disease, cancer, osteoporosis, and fracture … than those in the placebo group (HR, 0.60 [95% CI, 0.37-0.97]).19 Fractures Five trials reported on fracture … Evidence reviewed by the USPSTF showed that hormone therapy was associated with decreased risk of fracture … menopausal hormone therapy is approved for use in women with an increased risk of os- teoporosis and fracture

103. Recommendation: Breast Cancer: Medication Use to Reduce Risk | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction
     September 03, 2019 - Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene … Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis … Comparison of fracture, cardiovascular event, and breast cancer rates at 3 years in postmenopausal women … Effects of raloxifene on fracture risk in postmenopausal women: the Raloxifene Use for the Heart Trial … ND Mortality    Breast cancer ND NR NR    All-cause ND ND ND Fracture

104. Medication Use for the Risk Reduction of Primary Breast Cancer in Women: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/-TsBkyewVoFpC7htRmzWJa
     September 03, 2019 - Tamoxifen and raloxifene had similar effects on fracture incidence at multiple vertebral and nonvertebral … Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene … Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis … Comparison of fracture, cardiovascular event, and breast cancer rates at 3 years in postmenopausal women … Effects of raloxifene on fracture risk in postmenopausal women: the Raloxifene Use for The Heart Trial

105. Screening for and Management of Obesity in Adults: Clinical Summary of USPSTF Recommendation (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/Z-PbjsHwm4jWMadqNh9Pbz
     June 19, 2012 - harms of behavioral weight-loss interventions include decreased bone mineral density and increased fracture

106. Evidence Summary: Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/vitamin-supplementation-to-prevent-cvd-and-cancer-preventive-medication
     June 21, 2022 - Limited evidence suggested some supplements may be associated with higher risk of serious harms (hip fracture … Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals … Vitamin D supplementation and fracture incidence in elderly persons: a randomized, placebo-controlled … Effect of vitamin D(3) and calcium on fracture risk in 65- to 71-year-old women: a populationbased 3- … Vitamin A intake and the risk of hip fracture in postmenopausal women: the Iowa Women’s Health Study.

107. Home page | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/home
     January 01, 2025 - Recommendations Food Insecurity: Screening Osteoporosis to Prevent Fractures: Screening Iron Deficiency and Iron Deficiency Anemia During Pregnancy: Screening and Supplementation See More Search for Recommendations About the USPSTF Public Com…

108. Home page | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/
     January 01, 2025 - Recommendations Food Insecurity: Screening Osteoporosis to Prevent Fractures: Screening Iron Deficiency and Iron Deficiency Anemia During Pregnancy: Screening and Supplementation See More Search for Recommendations About the USPSTF Public Com…

109. Interventions to Prevent Falls in Older Adults: Updated Evidence Report and Systematic Review of the USPSTF (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/nMb54adBfgajp8dG87kPcw
     April 17, 2018 - For fracture out- comes, fall-related fractures was used preferentially in the meta- analysis, but if … , persons with a fracture, disability, quality of life, people hospitalized, and people who transitioned … For multifactorial interventions, while evi- dence for their effect on injuries or fracture was either … The certainty of the effects of fall prevention interventions on fracture is low because these outcomes … Effectiveness of a falls-and-fracture nurse coordinator to reduce falls: a randomized, controlled trial

110. Archived: Breast Cancer: Medications for Risk Reduction | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-medications-for-risk-reduction-2013
     September 15, 2013 - Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene … Comparison of fracture, cardiovascular event, and breast cancer rates at 3 years in postmenopausal women … Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis … difference All-cause mortality No difference No difference No difference Vertebral fracture … difference No difference 7 (5–9) fewer events per 1000 women with raloxifene Nonvertebral fracture

111. Archived: Vitamin D Deficiency: Screening | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/vitamin-d-deficiency-screening-november-2014
     November 24, 2014 - for fractures, and no studies, either individually or aggregated in meta-analysis, found a benefit on fracture … Osteoporosis and fracture risk in women of different ethnic groups.

112. Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/3Kwu7j_WfCFQSnSzqrDWwt
     June 20, 2019 - (8-20) ER− ND ND ND Noninvasive ND ND ND Mortality Breast cancer ND NR NR All-cause ND ND ND Fracture … Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene … Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis … Comparison of fracture, cardiovascular event, and breast cancer rates at 3 years in postmenopausal women … Effects of raloxifene on fracture risk in postmenopausal women: the Raloxifene Use for the Heart trial

113. Screening for Vitamin D Deficiency in Adults: US Preventive Services Task Force Recommendation (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/4BpSYQnx9MYzmKJSWQxrbC
     April 13, 2021 - 21 ng/mL and among participants with baseline levels less than 14 ng/mL.32,33 Six RCTs reported on fracture … compared with placebo (RR, 0.84 [95% CI, 0.58-1.21]).26 The USPSTF found only 1 trial reporting on hip fracture … In that study, only 1 hip fracture occurred, leading to a very imprecise effect estimate.34 In the WHI … case-control study, there was no association between treat- ment with vitamin D and calcium and clinical fracture … Osteoporosis and fracture risk in women of different ethnic groups.

114. Zvvry6Wa4Sgj-Ejb3Brcvy (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/zVVRY6wa4Sgj-EJb3BRcVy
     November 01, 2013 - single index, Freedman and colleagues assigned weights of 1.0 for life-threatening events (IBC, hip fracture … Efficacy of raloxifene on vertebral fracture risk reduction in postmenopausal women with osteoporosis … Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene … Comparison of fracture, cardiovascular event, and breast cancer rates at 3 years in postmenopausal women … No difference No difference 7 (5–9) fewer events per 1000 women with raloxifene Nonvertebral fracture

115. Screening for Vitamin D Deficiency in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/XCAMvXugbjnYnGmeF5GtUS
     April 13, 2021 - Fractures Nine RCTs17,19,26,27,35,44,51,52,54 reported fracture outcomes over 12 weeks to 3.3 years ( … eTable 5 in the Supplement); studies varied by type of fracture reported and ascertainment methods. … , but only 1 was conduc ted among community-dwel l ing populations52; only 1 hip fracture occurred, leading … supplementation in elderly women: confirmation of reversal of secondary hyperparathyroidism and hip fracture … Vitamin D supplementation and fracture incidence in elderly persons: a randomized, placebo-controlled

116. Vitamin and Mineral Supplements for the Primary Prevention of Cardiovascular Disease and Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/U4Vu9hcmHtD7snox6qbPja
     June 21, 2022 - Limited evidence suggested some supplements may be associated with higher risk of serious harms (hip fracture … Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals … Vitamin D supplementation and fracture incidence in elderly persons: a randomized, placebo-controlled … Effect of vitamin D(3) and calcium on fracture risk in 65- to 71-year-old women: a population- based … Vitamin A intake and the risk of hip fracture in postmenopausal women: the Iowa Women’s Health Study.

117. Draft Recommendation: Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: Preventive Medication | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/vitamin-supplementation-to-prevent-cvd-and-cancer-preventive-medication
     May 04, 2021 - the skin. 30 Two cohort studies in women showed a nonstatistically significant increased risk of hip fracture … study found that a high intake of vitamin B6 (≥35 mg/day) was associated with an increased risk of hip fracture … Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals … Vitamin A intake and the risk of hip fracture in postmenopausal women: the Iowa Women's Health Study. … Association of high intakes of vitamins B6 and B12 from food and supplements with risk of hip fracture

118. Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons: Clinician Summary of USPSTF Recommendation (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/GoN_zk54Asp3mBZ-MqsTjf
     November 01, 2022 - prevalence and incidence of most chronic diseases (eg, cardiovascular disease, cancer, osteoporosis, and fracture

119. Interventions to Prevent Falls in Community-Dwelling Older Adults: USPSTF Recommendation Statement (pdf file)
     www.uspreventiveservicestaskforce.org/home/getfilebytoken/h-w99jVsodSL33kV2h2_qW
     April 17, 2018 - .1,15 More than 90% of hip fractures are caused by falls, and 25% of older adults who sustain a hip fracture … CI, 0.97 to 1.61]).19 Four trials reported mixed results on the number of per- sons experiencing a fracture … a result of a fall and impact on the greater trochanter of the femur: a prospective controlled hip fracture

120. Recommendation: Falls Prevention in Community-Dwelling Older Adults: Interventions | United States Preventive Services Taskforce
     www.uspreventiveservicestaskforce.org/uspstf/recommendation/falls-prevention-community-dwelling-older-adults-interventions
     June 04, 2024 - were largely musculoskeletal discomfort and pain symptoms. 3 One trial reported a fall-related wrist fracture … , 17 and another reported a hip fracture attributed to an exercise session. 18 For trials studying