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81. Comparative Effectiveness of Treatments To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/osteoporosis/research

82. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/type-2-diabetes-medications-update_research-protocol.pdf
    April 06, 2010 - Evidence-based Practice Center Systematic Review Protocol Source: www.effectivehealthcare.ahrq.gov Published Online: April 06, 2010 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness and Safety of Oral Diabetes Medications for Adu…

83. Systematic Review of Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/breastfeeding_research-protocol.pdf
    January 01, 2020 - a reduced risk of type 2 diabetes and breast and ovarian cancer.2 No benefit was found for risk of fracture … cardiovascular outcomes (e.g., stroke, myocardial infarction) Replaced “osteoporosis” with “fracture … ” The evidence on osteoporosis and fracture risk has evolved since the original 2007 AHRQ report … was published; the most clinically relevant outcome is fracture (given that many fractures occur in … There is evidence on incidence of fracture associated with breastfeeding exposure.

84. Adverse Effects of First-Line Pharmacologic Treatments of Major Depression in Older Adults (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-depression-research-protocol.pdf
    February 07, 2018 - group (65 to 74y, 75 to 84y, and ≥85y) • Gender • Race or ethnicity • Risk of falls or history of fracture

85. Methods Guide for Comparative Effectiveness Reviews - Avoiding Bias in Selecting Studies (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-bias_methods.pdf
    February 01, 2013 - Does alendronate reduce the risk of fracture in men? … A meta-analysis incorporating prior knowledge of anti-fracture efficacy in women.

86. Update Topic Brief CER 27 NSD FINAL_SJ final (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
    January 17, 2014 - Update Topic Brief CER 27 NSD FINAL_SJ final Oral Diabetes Medications for Adults with Type 2 Diabetes Nomination Summary Document Results of Topic Selectio…

87. Menopause Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
    March 01, 2015 - long-term harms and potential benefits43 according to patient characteristics (e.g., lower risk of hip fracture

88. Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery: Systematic Review Update | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/thromboembolism-update/research-2017

89. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
    April 01, 2011 - “An increased risk of bone fracture is now added to this list, although the strength of association … The risk of fracture was increased in patients who received high-dose, defined as multiple daily doses

90. CER 173 Executive Summary: Diabetes Medications for Adults With Type 2 Diabetes: An Update (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/diabetes-update-2015_executive.pdf
    January 01, 2015 - strength of evidence from our prior Comparative Effectiveness Review for other outcomes (specifically fracture … based on pooled data from nine clinical trials (mean followup, 85 weeks) that showed incidences of fracture … active/placebo combined comparators.69 The labeling for canagliflozin notes that factors that increase fracture … Hospitalised hip fracture risk with rosiglitazone and pioglitazone use compared with other glucose-lowering … FDA revised label of diabetes drug canagliflozin (Invokana, Invokamet) to include updates on bone fracture

91. Disposition of Comments for Venous Thromboembolism Prophylaxis in Orthopedic Surgery (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_disposition-comments.pdf
    March 01, 2012 - We would expect hip fracture patients to have the highest PE incidence, followed by TKA (lesser), with … We analyzed the three surgeries (total hip replacement, total knee replacement, and hip fracture surgery … Appropriate prophylaxis in the Total Hip Replacement (THR), Total Knee Replacement (TKR) and Hip Fracture … used to answer this KQ is patients undergoing total hip replacement total knee replacement or hip fracture … We are specifically interested in the benefits of filter placement and removal in hip fracture patients

92. CER 210: Disposition of Comments for Breastfeeding Programs and Policies, Breastfeeding Uptake, and Maternal Health Outcomes in Developed Countries (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-disposition-comments.pdf
    January 01, 2020 - may be of interest to summarize the general direction of the association between breastfeeding and fracture … We have clarified when the grade refers to no association (for fracture). … We have clarified this in the table; specifically, we note that “low” for fracture refers to no association … The only harm presented is fracture risk. … Page 6, line 55 (page vii)-reword “We rated the evidence for association between breastfeeding and fracture

93. Cystic-Fibrosis-Hgh Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_surveillance.pdf
    August 01, 2012 - of required intravenous antibiotic treatments, frequency of hospitalization; quality of life; bone fracture … and bone mineralization are associated with improvements in health outcomes of quality of life, bone fracture … of required intravenous antibiotic treatments, frequency of hospitalization; quality of life; bone fracture … of required intravenous antibiotic treatments, frequency of hospitalization; quality of life; bone fracture … Do Not Know fracture.

94. Cervical Ripening in the Outpatient Setting (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/ocr-protocol-final_1.pdf
    December 18, 2019 - (confirmed sepsis or pneumonia)c • Meconium aspiration syndromec • Birth trauma (e.g., bone fracture … (confirmed sepsis or pneumonia)c • Meconium aspiration syndromec • Birth trauma (e.g., bone fracture … (confirmed sepsis or pneumonia)c • Meconium aspiration syndromec • Birth trauma (e.g., bone fracture … (confirmed sepsis or pneumonia)c • Meconium aspiration syndromec • Birth trauma (e.g., bone fracture

95. Type-2-Diabetes-Medications-Update Surveillance (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_surveillance.pdf
    December 31, 2013 - Fr ac tu re s The risk of fracture was higher for thiazolidinediones than for metformin. … The fracture rate was 4.1% in the reference (metformin) arm. (High) No new studies identified. … The fracture rate in the reference (metformin + sulfonylurea) arm was 1.6%. … The fracture rate was 4.1% in the reference (metformin) arm. … The fracture rate in the reference (metformin + sulfonylurea) arm was 1.6%.

96. CER 229 Evidence Summary: Opioid Treatments for Chronic Pain (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
    April 01, 2020 - • Six observational studies found an association between opioid use and risk of fracture and three

97. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/gestational-diabetes-screening-diagnosis_research-protocol.pdf
    December 16, 2011 - www.effectivehealthcare.ahrq.gov Published Online: December 16, 2011  Short-term: macrosomia, shoulder dystocia, clavicular fracture … obesity, hypertension o Fetal/neonatal/child  Short-term: macrosomia, shoulder dystocia, clavicular fracture …  Hypertension Fetal / neonatal / child outcomes  Macrosomia  Shoulder dystocia  Clavicular fracture

98. Disposition of Comments for CER 147 Menopausal Symptoms: Comparative Effectiveness of Therapies (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_disposition-comments.pdf
    March 05, 2015 - medical organizations recommend that menopausal HT is only indicated for menopausal symptoms, not for fracture … In the section addressing fracture outcomes for menopausal HT, this should be explicitly stated. … That is, it’s of interest to know the fracture outcome information, but guidelines uniformly recommend … gallbladder disease, colorectal cancer, cardiovascular disease (CVD), endometrial cancer, osteoporotic fracture

99. Comparative Effectiveness of Venous Thromboembolism (VTE) Prophylaxis in Orthopedic Surgery | Effective Health Care (EHC) Program
    effectivehealthcare.ahrq.gov/products/blood-clots-hip-knee-surgery/research-protocol

100. Treatments for Acute Pain: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-protocol-acute-pain-treatments.pdf
     August 08, 2019 - (back or spine or spinal or radicular or neck or musculoskeletal or fracture* or neuropathic or neuralgia … (back or spine or spinal or radicular or neck or musculoskeletal or fracture* or neuropathic or neuralgia