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effectivehealthcare.ahrq.gov/products/osteoporosis
December 17, 2007 - Comparative Effectiveness of Treatments To Prevent Fractures in Men and Women With Low Bone Density or Osteoporosis
Timeline
January 01, 2005
Topic Initiated
December 17, 2007
Systematic Review
Archived
Comparative Effectiveness of Treatments To Prevent Fract…
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effectivehealthcare.ahrq.gov/products/menopause/research-protocol
April 03, 2012 - for a detailed explanation). b Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture … Criteria
Inclusion/Exclusion
a Longitudinal studies of colorectal cancer, breast cancer, and fracture … Human AND “randomized controlled trial”(pt)
Osteoporotic Fractures
“Osteoporotic fractures” (mh) OR (fracture … ]/lim
#49 #17 AND #48
#50 #47 OR #49
#51 #25 AND #50
Osteoporotic Fractures
#52 ‘osteoporotic fracture … ’/exp OR ‘osteoporotic fractures’/exp OR (‘fracture’/exp OR ‘fractures’/exp AND (‘osteoporosis’/exp OR
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
June 12, 2013 - b Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture outcomes (does not apply … 1 yearb
Sample size >250
a Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture … yearsa
1 yearb
Sample size >250
a Longitudinal studies of colorectal cancer, breast cancer, and fracture … to
plausibly establish
causal effects: 5 years
for colorectal, breast,
or ovarian cancers and
fracture … ’/exp OR ‘osteoporotic fractures’/exp OR (‘fracture’/exp OR
‘fractures’/exp AND (‘osteoporosis’/exp
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_disposition-comments.pdf
September 15, 2014 - . ….association
between vitamin D exposure and fracture risk. … Can text be added to summarize fracture
results here? … We have added the post hoc analysis for breast
and colorectal cancer and for hip fracture
conducted … ES-12 notes that a non-significant relationship was
found for total fracture. … Since hip
fracture was a primary outcome in the WHI RCT
(whereas total fracture was a secondary outcome
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
March 25, 2012 - b Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture outcomes (does not apply … 1 yearb
Sample size >250
a Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture … yearsa
1 yearb
Sample size >250
a Longitudinal studies of colorectal cancer, breast cancer, and fracture … AND “randomized controlled trial”(pt)
Osteoporotic Fractures
“Osteoporotic fractures” (mh) OR (fracture … ’/exp OR ‘osteoporotic fractures’/exp OR (‘fracture’/exp OR
‘fractures’/exp AND (‘osteoporosis’/exp
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/radiation-therapy-bone-metastases
July 17, 2020 - These patients frequently experience morbidity from bone metastases, including pain, bone fracture, reduced … medication, need for further pain intervention, quality of life, rate of musculoskeletal event (such as bone fracture
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - (continued)
Fractures High The risk of fracture was higher for thiazolidinediones than for metformin … large RCT the RR was 1.57 (95% CI 1.13 to 2.17) and women in
the thiazolidinedione arm had a higher fracture … The
fracture rate was 4.1% in the reference (metformin) arm. … High The risk of fracture was higher for combination therapy with a
thiazolidinedione than for metformin … The fracture rate in the
reference (metformin + sulfonylurea) arm was 1.6%.
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effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
August 27, 2012 - Efficacy Weight of evidence
Turkish patients Weight of evidence Fracture … risk
Turkish physicians Renal toxicity Fracture risk
RTI International Research
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effectivehealthcare.ahrq.gov/products/cystic-fibrosis-hgh/research-protocol
January 22, 2010 - of required intravenous antibiotic treatments; frequency of hospitalization; quality of life; bone fracture … and bone mineralization are associated with improvements in health outcomes of quality of life, bone fracture … exercise tolerance, intravenous antibiotic use, hospitalizations, HRQoL, bone mineralization, bone fracture … Fractures, Bone/
36. bone fracture$.mp.
37. broken bones.mp.
38. … Fractures, Bone/
11. bone fracture$.mp.
12. broken bones.mp.
13.
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effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
March 01, 2010 - The final health outcomes include mortality, hospitalization, bone fracture, and health-related quality … of required intravenous antibiotic treatments, frequency of hospitalization, quality of life, bone fracture … and bone mineralization are associated with improvements in health outcomes of quality of life, bone fracture … of required intravenous antibiotic treatments, frequency of hospitalization, quality of life, bone fracture … and bone mineralization are associated with improvements in health outcomes of quality of life, bone fracture
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - broken up into adverse events (e.g., failure to deploy the device or
remove the clot, device breakage/fracture … The
adverse events of note include failure of the device to employ, breakage or fracture, perforation … GOS
Patients with
Acute
Ischemic
Stroke
Adverse outcomes
• Failure to Deploy
• Breakage/Fracture … Index or GOS) or
any harm (e.g., failure to deploy the device or remove the clot, device breakage/fracture … will include: failure to deploy the device or remove the clot (technical success), device
breakage/fracture
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - of required
intravenous antibiotic treatments; frequency of hospitalization; quality of life; bone fracture … and bone mineralization are associated with improvements in
health outcomes of quality of life, bone fracture … 2010 4
outcomes (which include health-related quality-of-life, hospitalization, bone fracture … exercise tolerance, intravenous antibiotic use,
hospitalizations, HRQoL, bone mineralization, bone fracture … Fractures, Bone/
36. bone fracture$.mp.
37. broken bones.mp.
38.
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effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
January 01, 2010 - Continued
exposure to oral corticosteroids may continue to
increase the risk of fracture associated … Use of
inhaled corticosteroids and the risk of fracture.
Chest. 2006;130:1082-8.
2. … The
risk of nonvertebral fracture related to inhaled
corticosteroid exposure among adults with chronic … Fracture risk associated with
inhaled corticosteroid use in chronic obstructive
pulmonary disease. … Fracture
risk in patients with chronic lung diseases treated
with bronchodilator drugs and inhaled
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-bone-metastases.pdf
February 01, 2017 - severe and debilitating effects
including pain, spinal cord compression, hypercalcemia,
and pathologic fracture … The evidence regarding an association between higher
risk for pathologic fracture after SF therapy vs … The evidence regarding an
association between higher risk for pathologic fracture after
SF therapy versus … intrafraction motion and that measure variables including
pain relief, local control, vertebral body fracture … defined as: presence of painful bone metastases
unassociated with impending or existing pathologic fracture
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effectivehealthcare.ahrq.gov/products/diabetes-update-2015/research-protocol
January 22, 2015 - 1 Strength of evidence on fractures was high in our previous report and indicated that the risk of fracture … including SGLT-2 inhibitors, urinary tract infections, impaired renal function, genital mycotic infections, fracture … include SGLT-2 inhibitors
Genital mycotic infections for comparisons that include SGLT-2 inhibitors
Fracture … given the high strength of evidence from our prior evidence report for other outcomes (specifically fracture … Hospitalised hip fracture risk with rosiglitazone and pioglitazone use compared with other glucose-lowering
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effectivehealthcare.ahrq.gov/sites/default/files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - Change in pain score after administration
of analgesics for lower extremity fracture pain during
hospitalization
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - Change in pain score after administration
of analgesics for lower extremity fracture pain during
hospitalization
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
October 12, 2023 - vs. 7
Grade 2: 18 vs. 11
Grade 3: 16 vs. 5
Grade 4: 0 vs. 0
Grade 5: 0 vs. 0
Vertebral compression fracture
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - 1 Strength of evidence on fractures was high in our previous report and indicated that the risk of fracture … SGLT-2 inhibitors, urinary tract infections, impaired renal function,
genital mycotic infections, fracture … SGLT-2 inhibitors, urinary tract infections, impaired
renal function, genital mycotic infections, fracture … SGLT-2 inhibitors
§ Genital mycotic infections for comparisons that include SGLT-2 inhibitors
§ Fracture … given the high strength of evidence from our prior evidence report for other outcomes (specifically
fracture
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effectivehealthcare.ahrq.gov/products/hip-feature-treatment-future/research