-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/blood-clots-hip-knee-surgery_executive.pdf
March 01, 2012 - surgical procedures including total hip
replacement (THR), total knee
replacement (TKR), and hip fracture … KQ 2: In patients undergoing major orthopedic surgery
(total hip or knee replacement or hip fracture … KQ 3: In patients undergoing major orthopedic surgery
(total hip or knee replacement or hip fracture … KQ 6: In patients undergoing major orthopedic surgery
(total hip or knee replacement or hip fracture … Hip Fracture Surgery (HFS): The surgical procedure to
treat hip fracture.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-disposition-comments.pdf
August 29, 2023 - Indications for surgery for each also
tend to be different, e.g., pathologic fracture in the femur is … Pathologic fracture in the spine
vertebral body is not always treated surgically, and often it is not … The listed
exclusion criterion for this study
was: Previous radiation therapy to
the fracture site … Author’s Table 1 lists
femoral and humeral fracture sites
in addition to “other” (7% vs. 3%)
which … While all of this infers that
treatment was of nonspine
fracture/impending fractures, it it’s
not
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - Insufficient
+ ++
All-cause death3 No difference No difference No difference Insufficient
+++ +++
Vertebral fracture … No difference No difference 7 (5, 9) 44 (25, 61)
+ +++ ++
Nonvertebral fracture Insufficient 3 (0.2
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - antidepressant
7 RCTs8,10-15
1 OBS26
Any AE, bleed-UGI, blood pressure, cognitive function, falls,
fracture
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/vitamin-d-calcium_disposition-comments.pdf
September 15, 2014 - . ….association
between vitamin D exposure and fracture risk. … Can text be added to summarize fracture
results here? … We have added the post hoc analysis for breast
and colorectal cancer and for hip fracture
conducted … ES-12 notes that a non-significant relationship was
found for total fracture. … Since hip
fracture was a primary outcome in the WHI RCT
(whereas total fracture was a secondary outcome
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause-protocol-130612.pdf
June 12, 2013 - b Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture outcomes (does not apply … 1 yearb
Sample size >250
a Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture … yearsa
1 yearb
Sample size >250
a Longitudinal studies of colorectal cancer, breast cancer, and fracture … to
plausibly establish
causal effects: 5 years
for colorectal, breast,
or ovarian cancers and
fracture … ’/exp OR ‘osteoporotic fractures’/exp OR (‘fracture’/exp OR
‘fractures’/exp AND (‘osteoporosis’/exp
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/menopause_research-protocol.pdf
March 25, 2012 - b Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture outcomes (does not apply … 1 yearb
Sample size >250
a Longitudinal studies of colorectal, breast, or ovarian cancers; and fracture … yearsa
1 yearb
Sample size >250
a Longitudinal studies of colorectal cancer, breast cancer, and fracture … AND “randomized controlled trial”(pt)
Osteoporotic Fractures
“Osteoporotic fractures” (mh) OR (fracture … ’/exp OR ‘osteoporotic fractures’/exp OR (‘fracture’/exp OR
‘fractures’/exp AND (‘osteoporosis’/exp
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - (continued)
Fractures High The risk of fracture was higher for thiazolidinediones than for metformin … large RCT the RR was 1.57 (95% CI 1.13 to 2.17) and women in
the thiazolidinedione arm had a higher fracture … The
fracture rate was 4.1% in the reference (metformin) arm. … High The risk of fracture was higher for combination therapy with a
thiazolidinedione than for metformin … The fracture rate in the
reference (metformin + sulfonylurea) arm was 1.6%.
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/research-gap-primary-care-summary-table.pdf
March 01, 2022 - ........................ 25
vi
Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture … Interventions
• Randomized controlled trials with adequate power
to compare risk of clinical fracture … endpoints for
osteoporosis drugs that don’t yet have established
long-term fracture prevention efficacy … • Randomized controlled trials with adequate power
to compare risk of clinical fracture endpoints … • Randomized controlled trials with adequate power
to compare risk of clinical fracture endpoints
-
effectivehealthcare.ahrq.gov/sites/default/files/johnson_-ahrq-mcda-presentation.pdf
August 27, 2012 - Efficacy Weight of evidence
Turkish patients Weight of evidence Fracture … risk
Turkish physicians Renal toxicity Fracture risk
RTI International Research
-
effectivehealthcare.ahrq.gov/sites/default/files/topic-refinement.ppt
March 01, 2010 - The final health outcomes include mortality, hospitalization, bone fracture, and health-related quality … of required intravenous antibiotic treatments, frequency of hospitalization, quality of life, bone fracture … and bone mineralization are associated with improvements in health outcomes of quality of life, bone fracture … of required intravenous antibiotic treatments, frequency of hospitalization, quality of life, bone fracture … and bone mineralization are associated with improvements in health outcomes of quality of life, bone fracture
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - broken up into adverse events (e.g., failure to deploy the device or
remove the clot, device breakage/fracture … The
adverse events of note include failure of the device to employ, breakage or fracture, perforation … GOS
Patients with
Acute
Ischemic
Stroke
Adverse outcomes
• Failure to Deploy
• Breakage/Fracture … Index or GOS) or
any harm (e.g., failure to deploy the device or remove the clot, device breakage/fracture … will include: failure to deploy the device or remove the clot (technical success), device
breakage/fracture
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - of required
intravenous antibiotic treatments; frequency of hospitalization; quality of life; bone fracture … and bone mineralization are associated with improvements in
health outcomes of quality of life, bone fracture … 2010 4
outcomes (which include health-related quality-of-life, hospitalization, bone fracture … exercise tolerance, intravenous antibiotic use,
hospitalizations, HRQoL, bone mineralization, bone fracture … Fractures, Bone/
36. bone fracture$.mp.
37. broken bones.mp.
38.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/topic-nomination-bone-metastases.pdf
February 01, 2017 - severe and debilitating effects
including pain, spinal cord compression, hypercalcemia,
and pathologic fracture … The evidence regarding an association between higher
risk for pathologic fracture after SF therapy vs … The evidence regarding an
association between higher risk for pathologic fracture after
SF therapy versus … intrafraction motion and that measure variables including
pain relief, local control, vertebral body fracture … defined as: presence of painful bone metastases
unassociated with impending or existing pathologic fracture
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_4-user-guide-to-ocer_130129.pdf
January 01, 2010 - Continued
exposure to oral corticosteroids may continue to
increase the risk of fracture associated … Use of
inhaled corticosteroids and the risk of fracture.
Chest. 2006;130:1082-8.
2. … The
risk of nonvertebral fracture related to inhaled
corticosteroid exposure among adults with chronic … Fracture risk associated with
inhaled corticosteroid use in chronic obstructive
pulmonary disease. … Fracture
risk in patients with chronic lung diseases treated
with bronchodilator drugs and inhaled
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-220-analgesics-acute-pain-summary.pdf
September 01, 2019 - Change in pain score after administration
of analgesics for lower extremity fracture pain during
hospitalization
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
January 01, 2015 - 1 Strength of evidence on fractures was high in our previous report and indicated that the risk of fracture … SGLT-2 inhibitors, urinary tract infections, impaired renal function,
genital mycotic infections, fracture … SGLT-2 inhibitors, urinary tract infections, impaired
renal function, genital mycotic infections, fracture … SGLT-2 inhibitors
§ Genital mycotic infections for comparisons that include SGLT-2 inhibitors
§ Fracture … given the high strength of evidence from our prior evidence report for other outcomes (specifically
fracture
-
effectivehealthcare.ahrq.gov/products/hip-feature-treatment-future/research
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
May 29, 2025 - vs. 7
Grade 2: 18 vs. 11
Grade 3: 16 vs. 5
Grade 4: 0 vs. 0
Grade 5: 0 vs. 0
Vertebral compression fracture
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-210-breastfeeding-evidence-summary.pdf
January 01, 2020 - Reproductive history
and postmenopausal risk of hip and forearm fracture. … Dietary calcium intake, physical
activity and the risk of vertebral fracture in Chinese. … Parity, lactation and hip
fracture. Osteoporos Int. 1993 Jul;3(4):171-6. PMID: 8338971.
136. … An epidemiologic study
of hip fracture in postmenopausal women. … Influence of
parity and lactation on hip fracture risk.