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1. Recommendation: Prevention of Dental Caries in Children Younger Than 5 Years: Screening and Interventions | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/prevention-of-dental-caries-in-children-younger-than-age-5-years-screening-and-interventions1
   December 07, 2021 - supply is deficient in fluoride (<0.6 parts fluoride per million parts water [ppm F]). … Typically, fluoride varnish is applied with a small brush and is available as 5% sodium fluoride (2.26% … fluoride). … in young children (typically available as 5% sodium fluoride [2.26% fluoride]). … In studies, fluoride varnish was most commonly administered as 5% sodium fluoride, every 6 months. 1

2. Screening and Interventions to Prevent Dental Caries in Children Younger Than 5 Years: US Preventive Services Task Force Recommendation Statement (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/wTL2utcBK9_czS8WDWaNT6
   December 07, 2021 - (typically available as 5% sodium fluoride [2.26% fluoride]). … supply is deficient in fluoride (<0.6 parts fluoride per million parts water [ppm F]). • Apply: Apply … Typically, fluoride varnish is applied with a small brush and is available as 5% sodium fluoride (2.26% … fluoride). … In studies, fluoride varnish was most commonly administered as 5% sodium fluoride, every 6 months.1

3. Archived: Dental Caries in Children from Birth Through Age 5 Years: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/recommendation/dental-caries-in-children-from-birth-through-age-5-years-screening-2014
   May 05, 2014 - fluoride in their water and application of fluoride varnish to the primary teeth of all children can … other topical fluoride interventions, systematic exposure to fluoride is low after varnish application … The trials compared fluoride varnish applied every 6 months with no fluoride varnish. … fluoride in the water supply. … Comparative anti-caries effects of tablet and liquid fluorides in cleft children.

4. Materials X (pdf file)
   www.ahrq.gov/sites/default/files/wysiwyg/policymakers/chipra/factsheets/fullreports/chipra-164-materials-x.pdf
   June 02, 2025 - B: Fluoride  Tx -­‐ At least one claim PREV_B_1 Prev. Grp. … B: Fluoride  Tx -­‐ 1 claim PREV_B_2 Prev. Grp. B: Fluoride  Tx -­‐ 2 claims PREV_B_3 Prev. … B: Fluoride  Tx -­‐ 3 claims PREV_B_4 Prev. Grp. … B: Fluoride  Tx -­‐ 4+ claims PREV_B_CLM Prev. Grp. … B: Fluoride  Tx -­‐ Claim Indicator PREV_B_CNT Prev. Grp.

5. Evidence Summary: Prevention of Dental Caries in Children Younger Than 5 Years: Screening and Interventions | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/prevention-of-dental-caries-in-children-younger-than-age-5-years-screening-and-interventions1
   December 07, 2021 - Dietary fluoride supplementation and fluoride varnish were associated with improved caries outcomes in … One trial 38 evaluated acidulated phosphate fluoride foam and the others evaluated fluoride varnish. … Fluoride varnish was most commonly administered as 5% sodium fluoride every 6 months. … phosphate fluoride foam. … Comparative anti-caries effects of tablet and liquid fluorides in cleft children.

6. Prevention of Dental Caries in Children From Birth Through Age 5 Years: USPSTF Recommendation Statement (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/aHH-PY8unwJXW5NqJhRUz6
   May 01, 2014 - supplemen- tation, in childrenwhohave low levels of fluoride in their water and application of fluoride … other topical fluoride interventions, systematic ex- posure to fluoride is low after varnish application … The trials com- pared fluoride varnish applied every 6 months with no fluoride varnish. … fluoride in the water supply. … Comparative anti-caries effects of tablet and liquid fluorides in cleft children.

7. Screening and Interventions to Prevent Dental Caries in Children Younger Than 5 Years: Updated Evidence Report and Systematic Review for the USPSTF (pdf file)
   www.uspreventiveservicestaskforce.org/home/getfilebytoken/vv5kXtX5QDg2948gog66pd
   December 07, 2021 - Dietary fluoride supplementation and fluoride varnish were associated with improved caries outcomes in … fluoride. … Fluoride varnish was most commonly administered as 5% sodium fluoride every 6 months. … fluoride foam. … Comparative anti-caries effects of tablet and liquid fluorides in cleft children.

8. Evidence Summary: Oral Health in Children and Adolescents Aged 5 to 17 Years: Screening and Preventive Interventions | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/oral-health-children-adolescents-screening-preventive-interventions
   November 07, 2023 - An evaluation of the utility of application and cariostatic effectiveness of phosphate-fluorides in solution … Effectiveness of fortnightly tooth brushing with amine fluorides in caries-prone subjects. … Clinical study of an amine fluoride gel and acidulated phosphate fluoride gel. … Fluorides in community programs; a study of four years of various fluorides applied topically to the … Randomized trial on fluorides and sealants for fissure caries prevention.

9. Archived: Final Evidence Summary: Dental Caries in Preschool Children: Screening | United States Preventive Services Taskforce
   www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary19/dental-caries-in-preschool-children-screening-2004
   April 15, 2004 - The evidence for effectiveness of supplemental fluorides, fluoride varnish, and counseling for caries … RCTs) Meta-analysis indicates 1.8 surface reduction associated with interventions increasing use of fluorides … Fluoride supplements. … fluoride in the water supply. … Comparative anti-caries effects of tablet and liquid fluorides in cleft children.

10. Prevention of Dental Caries in Children from Birth Through Age 5 Years: Clinical Summary of USPSTF Recommendtion (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/CW5D3p7B-oRYDVKrhH5REv
    supplementation starting at age 6 months for children whose water supply is deficient in fluoride … Grade: B Apply fluoride varnish to the primary teeth of all infants and children starting at the … All children with erupted primary teeth can benefit from the periodic application of fluoride varnish … , regardless of the levels of fluoride in their water. … There is a moderate net benefit of providing fluoride varnish application to all children starting

11. Materials VI-B (pdf file)
    www.ahrq.gov/sites/default/files/wysiwyg/policymakers/chipra/factsheets/fullreports/chipra-164-materials-vi-b.pdf
    June 02, 2025 - 8.774 9.197 10.275 10.033 10.524 27.891 26.533 29.317 7.873 7.713 9.147 8.957 25.058 23.897 Fluoride … 3.982 4.078 11.679 10.222 13.345 5.755 5.706 5.804 4.836 4.788 4.884 8.743 8.551 8.939 7.762 7.613 Fluoride … 18.086 17.349 18.853 24.859 23.035 26.827 6.948 6.809 8.396 8.224 16 15.392 21.525 20.029 Fluoride … 3 0.6469 <.0001 4+ 0.667 <.0001 Fluoride Treatment Medical Provider‐At least one claim ‐0.0134 … 4+ ‐0.0472 0.4973 Fluoride Treatment Dental Provider‐At least one claim 0.3632 <.0001 Fluoride

12. Physicians’ Roles in Preventing Dental Caries in Preschool Children: A Summary of the Evidence (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/xXX8ZeqpmqtMURtJSfub56
    April 01, 2004 - Study, year Response rate %, (n) Venue, % optimal fluoride Physician type Prescribe fluoride … RCTs) Meta-analysis indicates 1.8 surface reduction associated with interventions increasing use of fluorides … Fluoride supplements. … fluoride in the water supply. … Comparative anti-caries effects of tablet and liquid fluorides in cleft children.

13. Archived: Dental Caries in Preschool Children: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/dental-caries-in-preschool-children-screening-2004
    April 15, 2004 - Fluoride varnishes, professionally applied topical fluorides approved to prevent dental caries in young … supplements that may lead to excessive fluoride intake. … Professional topical fluoride application is an adjunct to oral fluoride supplementation used for the … Fluoride supplements and fluorosis: a meta-analysis. … Review of fluoride: benefits and risk. Washington, DC: U.S.

14. Screening and Interventions to Prevent Dental Caries in Children Younger Than 5 Years (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/uGHrtWxfCQm8wS7hgyQj_B
    December 01, 2021 - Children younger than 5 years: B Grade Prescribe oral fluoride supplementation starting at age 6 months … for children whose water supply is deficient in fluoride. … Children younger than 5 years: B Grade Apply fluoride varnish to the primary teeth of all infants … supply is deficient in fluoride (<0.6 parts fluoride per million parts water [ppm F]) … Typically, fluoride varnish is applied with a small brush and is available as 5% sodium fluoride (2.26

15. Screening, Referral, Behavioral Counseling, and Preventive Interventions for Oral Health in Children and Adolescents Aged 5 to 17 Years: A Systematic Review for the USPSTF (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/9AtjNaSwTXonz49w_DEbNz
    November 07, 2023 - An evaluation of the utility of application and cariostatic effectiveness of phosphate-fluorides in solution … Effectiveness of fortnightly tooth brushing with amine fluorides in caries-prone subjects. … Clinical study of an amine fluoride gel and acidulated phosphate fluoride gel. … Fluorides in community programs; a study of four years of various fluorides applied topically to the … Randomized trial on fluorides and sealants for fissure caries prevention.

16. Archived: Final Recommendation Statement: Dental Caries in Preschool Children: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/dental-caries-in-preschool-children-screening-2004
    April 15, 2004 - Fluoride varnishes, professionally applied topical fluorides approved to prevent dental caries in young … supplements that may lead to excessive fluoride intake. … Professional topical fluoride application is an adjunct to oral fluoride supplementation used for the … Fluoride supplements and fluorosis: a meta-analysis. … Review of fluoride: benefits and risk. Washington, DC: U.S.

17. Archived: Final Evidence Summary: Dental Caries in Children from Birth Through Age 5 Years: Screening | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary2/dental-caries-in-children-from-birth-through-age-5-years-screening-2014
    June 15, 2013 - How effective is preventive treatment (dietary fluoride supplementation, topical fluoride application … USPSTF review evaluated fluoride varnish (2.26% F) applied every 6 months versus no fluoride varnish … Dietary fluoride supplementation and fluoride varnish are primary care–feasible interventions that appear … Comparative anti-caries effects of tablet and liquid fluorides in cleft children. … c In the fluoride varnish treatment group, some children received a placebo varnish instead of fluoride

18. Prevention of Dental Caries in Preschool Children - Recommendations and Rationale (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/TuWmfBsDp6S9NXjTHNdGou
    April 01, 2004 - • Fluoride varnishes, professionally applied topical fluorides approved to prevent dental caries in … supplements that may lead to excessive fluoride intake. … Professional topical fluoride application is an adjunct to oral fluoride supplementation used for the … Fluoride supplements and fluorosis: a meta-analysis. … Review of fluoride: benefits and risk. Washington, DC: U.S.

19. Preventing Dental Caries in Children <5 Years: Systematic Review Updating USPSTF Recommendation (pdf file)
    www.uspreventiveservicestaskforce.org/home/getfilebytoken/BM-D2tSCN9U8uuBFAufXaa
    August 01, 2013 - How effective is preventive treat- ment (dietary fluoride supplemen- tation, topical fluoride application … How effective is preventive treatment with topical fluoride application (fluoride varnish) in preventing … Dietary fluoride sup- plementation and fluoride varnish are primary care–feasible interven- tions that … Effectiveness of silver diamine fluoride and sodium fluoride varnish in arresting dentin caries in Chi … Comparative anti-caries effects of tablet and liquid fluorides in cleft children.

20. Recommendation: Oral Health in Children and Adolescents Aged 5 to 17 Years: Screening and Preventive Interventions | United States Preventive Services Taskforce
    www.uspreventiveservicestaskforce.org/uspstf/recommendation/oral-health-children-adolescents-screening-preventive-interventions
    November 07, 2023 - Fluoride Among 7 trials that evaluated fluoride supplements vs placebo or no fluoride in children 5 … Fluoride use in caries prevention in the primary care setting.  … Fluoride therapy . In: The Reference Manual of Pediatric Dentistry .  … Research is needed to assess the effectiveness and harms of fluoride gel, fluoride varnish, sealants, … silver diamine fluoride, and xylitol on oral health conditions.