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121. Pharmacokinetic/Pharmacodynamic Measures for Guiding Antibiotic Treatment for Nosocomial Pneumonia | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/pneumonia-antibiotic-treatment/research-protocol
     December 01, 2019 - cause of hospital-acquired infection in the intensive care unit (ICU). 1 In the ICU setting, it accounts … HAP may be managed in a hospital ward or in the intensive care unit (ICU) when the illness is more severe … HCAP is a pneumonia that develops in any patient who was hospitalized in an acute care hospital for 2 … the hospital (emergency department, floor, or ICU) Treatment continuing in other settings (e.g., in … Includes pneumonia in any patient who was hospitalized in an acute care hospital for 2 or more days within

122. Frameworks for Determining Research Gaps During Systematic Reviews (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-future-research-steps-framework_research.pdf
     June 01, 2011 - short and why the evidence falls short. … Examples of settings include: at home, in the hospital, in the outpatient setting, in the United States … short and why the evidence falls short. … According to a formal procedure, the staff of UVT advise the hospitals management in difficult resource … HTA Unit in A. Gemelli Teaching Hospital (cont.)

123. Physiologic Predictors of the Need for Trauma Center Care: A Systematic Review (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/predictors-trauma-care_research-protocol.pdf
     May 31, 2017 - Patients without serious injuries can be treated effectively outside of major trauma centers and at hospitals … the patient as most seriously injured, step three considers the details mechanism of injury (i.e., falls … and in-hospital treatment (i.e., a person can have a serious injury and recover). … the field, and during transport (referred to as out-of-hospital or in the field). … countries with out-of-hospital care systems that differ from those in the United States

124. Pressure Ulcer Treatment Strategies: A Comparative Effectiveness Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/pressure-ulcer-treatment/research-protocol
     December 01, 2019 - acute-care hospitals, from 2.2 to 23.9 percent in long-term nursing facilities, and from 0 to 17 percent … of treatment strategies differ according to patient care settings such as home, nursing facility, or hospital … of treatment strategies differ according to patient care settings such as home, nursing facility, or hospital … Any duration of followup Settings Patient care settings, such as home, nursing facility, or hospital … Effect of pressure ulcers on length of hospital stay.

125. Schwitzer_ECCS2012 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/schwitzer_eccs2012.pdf
     July 23, 2012 - Slide 6: Overarching  Themes  (1 of 2) • There is far too much “stenography” in … the reporting of health news. • There is not enough independent vetting  of studies  in journals … 1 of 6) • The news coverage of this recommendation was perhaps the most biased coverage I’ve seen in … "In my practice, we find men in their 30s and 40s [who] are at high-­‐risk and  develop prostate   … o He eventually  decided to  undergo  surgery:  “When you see the  people   around you falling

126. Asthma-Immunotherapy-2010 Research-Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2010_research-protocol.pdf
     January 01, 2010 - Mary’s Hospital in the United Kingdom in 1955 and for Lowell and Franklin38 at the Massachusetts General … Hospital in 1963 to finally carry out controlled studies with SCIT. … pyridine-extracted alum extracts [not available in U.S. except in clinical trials; some approved in … skin test reactivity" (in-vivo) and "change in antibody" (in-vitro) are accepted indicators of a therapeutic … airways in a controlled fashion in order to induce asthma symptoms.

127. Procalcitonin for Diagnosis and Management of Sepsis | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/procalcitonin/research-protocol
     December 01, 2019 - evidence that procalcitonin is more specific for bacterial infections with serum levels rising and falling … 3 months Settings Outpatient: ambulatory clinics, urgent care centers Inpatient: hospital … Specifically, outcomes such as antibiotic use/duration and hospital/ICU length of stay are determined … Among the key outcomes considered in this review were antibiotic use/duration and hospital/ICU … Resources to Prevent Hospital-Acquired Infections White Paper Jul 27, 2023 Making

128. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
     November 08, 2011 - acute-care hospitals, from 2.2 to 23.9 percent in long-term nursing facilities, and from 0 to 17 percent … treatment strategies differ according to patient care settings such as home, nursing facility, or hospital … treatment strategies differ according to patient care settings such as home, nursing facility, or hospital … Any duration of followup Settings  Patient care settings, such as home, nursing facility, or hospital … Effect of pressure ulcers on length of hospital stay.

129. Evidence Summary-Comparative-Effectiveness-Review-213-Lower-Limb-Prostheses (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-213-lower-limb-protheses-evidence-summary.pdf
     September 01, 2018 - for test accuracy to predict two or more falls during a 6-month followup period.7 The Turn Time and … Test, FSST and TUG all had high sensitivity (85% to 100%) and specificity (74% to 93%) to predict falls … Advanced components portion of LCI-4 had high specificity (91%) but low sensitivity (43%) to predict falls … of the 180 Degree Turn Test also had high sensitivity (85%) but low sensitivity (31%) to predict falls … However, only one of the studies was conducted in the United States and it used hospital data as of

130. Nitrous Oxide for the Management of Labor Pain | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/labor-nitrous-oxide/research-protocol
     December 01, 2019 - the U.S. 2 A 2002 review of labor pain management strategies used in U.S. hospitals—stratified by number … of yearly births and size of hospital—found that, among women who gave birth in 1997, from 21 to 50 … relief in 1991, 5 and a 1995 survey of hospitals in Ontario, Canada, found that nitrous oxide was available … for labor pain analgesia in 75% of responding hospitals. 6 Nitrous oxide is also commonly used for … Setting All birth settings will be considered, including hospital, birth center, and home.

131. Evidence-based Practice Center Systematic Review Protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
     January 10, 2012 - of the incidence of pressure ulcers range from 0.4 to 38 percent in acute care hospitals, from 2 to … a separate review) *Setting includes hospital, long-term care facility, rehabilitation facility, … Settings Include:  Acute care hospital, long-term care facility, rehabilitation facility, … Effect of pressure ulcers on length of hospital stay. … hospital.

132. Suicide Prevention | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/suicide-prevention/research-protocol
     January 01, 2020 - The following data systems can be used to study suicide morbidity: hospital discharges for self-inflicted … in 1999. … Highway Traffic Safety Administration, Health Resources and Services Administration National Hospital … Ambulatory Medical Care Survey https://cdc.gov/nchs/ahcd/about_ahcd.htm USDHHS, CDC National Hospital … Care Survey https://cdc.gov/nchs/nhcs.htm USDHHS, CDC National Hospital Discharge Survey

133. Layout 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
     April 01, 2007 - in the practice of medicine. … Recruitment typically occurs at several levels, including facilities (hospital, practice, pharmacy), … Quality assurance aims to affirm that the data were, in fact, collected in accordance with established … marketed products is dependent on the principle of “becoming aware,” collection of adverse event data falls … are important in one scenario may be less important in another.

134. Disposition of Comments for Evidence Report #208 Part 5 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_disposition-comments.pdf
     July 26, 2012 - The other chapters report on providers that are organizations (hospitals, health plans, long-term care … limited cases of nursing home and hospital care (even then, for hospital care that is emergency or … based on a doctor's referral or in a one-hospital region, the consumer isn't making a choice). … the study how many patients opted out of the registry in New York and non-New York hospitals, the … the case of hospitals), the introductory section on Hospitals (p. 26), the Description of Quantitative

135. For adult patients with bipolar disorder (including bipolar I and bipolar II disorder), what is the comparative effectiveness of available treatments including psychotherapy, other psychosocial treatments, medications, and other somatic… | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/nominated-topics/for-adult-patients-with-bipolar-disorder-including-bipolar-i-and-bipolar-ii-disorder-what-is-the-comparative-effectiveness-of-available-treatments-including-psychotherapy-other-psychosocial-treatments-medications-and-other-s
     November 01, 2017 - (For example, improvements in patient symptoms or problems from treatment or diagnosis.) … In 2011, APA revised its guideline development process in accordance with new standards recommended by … (For example, variations in clinical care, controversy in what constitutes appropriate clinical care, … Describe the timeframe in which an answer to your question is needed. … In a study of Medicaid claims data, Busch et al. (2009) found disparities in the use of antimanic medications

136. Pneumonia-Antibiotic-Treatment Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_executive.pdf
     November 01, 2014 - The incidence rates for HAP, which can occur in all areas of hospitals, range from 5 to more than … 20 per 1,000 admissions.1,2 HAP is the leading cause of hospital- acquired infection in the intensive … Clinicians may manage HAP patients in a hospital ward or in an ICU when the illness is more severe … all acute care hospitals in the United States.36 Pharmacodynamic dose optimization has been suggested … High prevalence of multidrug- resistant nonfermenters in hospital-acquired pneumonia in Asia.

137. pneumonia-antibiotic-treatment-protocol-130718 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pneumonia-antibiotic-treatment_research-protocol.pdf
     July 19, 2013 - HAP may be managed in a hospital ward or in the intensive care unit (ICU) when the illness is more severe … • HCAP is a pneumonia that develops in any patient who was hospitalized in an acute care hospital … the hospital (emergency department, floor, or ICU)  Treatment continuing in other settings (e.g … ., in the home or in a skilled nursing facility)  Pneumonia developing in the hospital Treatment … Includes pneumonia in any patient who was hospitalized in an acute care hospital for 2 or more days

138. Systematic Review on Opioid Treatments for Chronic Pain: Surveillance Report 1 (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/opioids-chronic-pain-surveillance-report-1-final.pdf
     April 01, 2022 - Mixed mechanism vs. opioid agonist and mortality, falls/fracture, hospitalization for adverse event … risk of mortality, falls/fracture, or safety event hospitalizations SOE insufficient, based on … insurance found tramadol (a mixed mechanism agent) associated with similar risk of all-cause mortality, falls … overdose (intentional and unintentional); and (3) other harms, including gastrointestinal-related harms, falls … Effectiveness of interventions on the appropriate use of opioids for noncancer pain among hospital

139. Management of Insomnia Disorder in Adults: Current State of the Evidence (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/insomnia_clinician.pdf
     August 01, 2017 - b The effectiveness of CBT-I was demonstrated across modes of delivery: in-person as an individual, in-person … Sleep-driving and other complex behaviors while not fully awake �� Worsening depression or suicidal thoughts �� Falls … statements in the FDA labels. … Gaps in Knowledge and Other Issues �� Evidence regarding the effects of insomnia interventions in … Sleep Restriction Interventions to limit time in bed to sleep time and to gradually increase time in

140. Medication-Therapy-Management Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medication-therapy-management_executive.pdf
     November 01, 2014 - This review does not address (1) MTM services provided within inpatient settings or shortly after hospital … the MTM program) – Patient-centered outcomes � Disease-specific morbidity, including falls and fall-related … time of hospital discharge or shortly after (e.g., within a few weeks) Relevant factors: • The MTM … Length of hospital stay RCT: 1 (208) Insufficient Low study limitations, consistency unknown, direct … In fact, many studies were able to measure changes in this outcome only in the intervention group.