-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/icd-categories-prevalence-reimbursement_research.pdf
January 01, 2011 - billion in expenditures.8 Multiple comorbidities further
contribute to high spending by Medicare; heart failure … cerebral degenerations (331) 70,626 81,089 678.6
390-459 Diseases of the circulatory system heart failure … hernia (560)
162,311 186,945 1,541.9
580-629 Diseases of the genitourinary system acute renal failure … cerebral degenerations (331) 22,876 70,941 173.7
390-459 Diseases of the circulatory system heart failure … Assessment of
cost and health resource utilization for elderly patients with
heart failure
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - Outcomes: The outcomes are broken up into adverse events (e.g., failure to deploy the device or
remove … The
adverse events of note include failure of the device to employ, breakage or fracture, perforation … mRS
NIHSS
Barthel Index
GOS
Patients with
Acute
Ischemic
Stroke
Adverse outcomes
• Failure … recanalization, mortality, mRS, or outcome score including NIHSS, Barthel Index or GOS) or
any harm (e.g., failure … Harms will include: failure to deploy the device or remove the clot (technical success), device
breakage
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/plasma-cell-dyscrasias-sflc-assay_research-protocol.pdf
May 02, 2011 - marrow plasma cells ≤10%
Absence of end-organ damage (bone lesions, anemia,
hypercalcemia, or renal failure … monoclonal protein
Evidence of end-organ damage (bone lesions, anemia,
hypercalcemia, or renal failure … plasma cells ≥10%
Absence of end-organ damage (bone lesions, anemia,
hypercalcemia, or renal failure … early relapse, stringent
complete response, or a partial response; the earlier prediction of drug failure … who have not been diagnosed with a PCD but who have nonspecific
symptoms (with or with out kidney failure
-
effectivehealthcare.ahrq.gov/sites/default/files/santa_eccs2012.pdf
February 01, 2013 - Heartburn medications
o Anti-‐inflammatory drugs
• Disease
approach
o Cancer
o Chronic
kidney
failure … ‐language versions of selected topics
• Longer “stories” about more complex topics: chronic renal failure … American Society of Clinical Oncology): “Even in cancer, more may
not be better.”
• Chronic
renal failure
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/assessing-applicability.ppt
January 01, 2009 - In heart failure trials, two-thirds of white patients have heart failure as a result of ischemic heart … However, two-thirds of African Americans have heart failure as a result of long-standing hypertension … setting
Trial Population Intervention Comparator Outcomes, Setting Comments
Smith et al.24 Heart failure … This is similar to the population with heart failure in the United States. … This is similar to the population with heart failure in the United States.
-
effectivehealthcare.ahrq.gov/sites/default/files/assessing-applicability.ppt
January 01, 2009 - In heart failure trials, two-thirds of white patients have heart failure as a result of ischemic heart … However, two-thirds of African Americans have heart failure as a result of long-standing hypertension … setting
Trial Population Intervention Comparator Outcomes, Setting Comments
Smith et al.24 Heart failure … This is similar to the population with heart failure in the United States. … This is similar to the population with heart failure in the United States.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_overview.pdf
June 24, 2014 - including death from cardiovascular or renal
causes, stroke, myocardial infarction, congestive heart failure
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_executive.pdf
June 01, 2011 - aimed at modifying the renin system have
been used extensively for treatment of hypertension,
heart failure … importance such as
individuals with essential hypertension and diabetes
mellitus, congestive heart failure … on findings from studies
evaluating patients with other, related conditions
such as congestive heart failure … agents
studied here have been compared in large studies
for related conditions such as congestive heart
failure
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hypertension-pulmonary-arterial_research-protocol.pdf
January 30, 2013 - unrelieved, progresses to right ventricular pressure overload, dysfunction, and
ultimately right heart failure … Long-term outcomes
Functional class
Quality of life (e.g., SF-36, Minnesota Living With Heart Failure … [MLWHF], Cambridge Pulmonary Hypertension Outcome Review
[CAMPHOR])
Right heart failure
Mortality … SF-36, MLWHF, CAMPHOR)
Prevention of right ventricular dysfunction and/or right heart failure
Mortality … , and
6-minute walk
o Long-term outcomes such as functional
class, quality of life, right heart failure
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - Specific adverse events evaluated include
CV [stroke, myocardial infarction, congestive heart
failure … Moderate for previous
bleeding
Moderate for hypertension,
edema, ischemic heart disease,
heart failure … Following hospitalization for heart failure, one large
observational study found celecoxib and diclofenac … ibuprofen or naproxen, and another large observational
study found an increased risk of repeat heart failure … CHF = congestive heart failure; CI = confidence interval; CLASS = Celecoxib Long-term Arthritis Safety
-
effectivehealthcare.ahrq.gov/sites/default/files/blumenthal-presentation.pdf
May 29, 2025 - my colleagues decision
making around
end-‐of-‐life decisions,
where
end-‐stage heart failure … and
values is that sometimes differences in
culture between providers and patients can cause failure … Going
back to the study that we did
with
the end-‐stage heart failure patients who were being
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_executive.pdf
April 01, 2012 - What is the range of recommended
clinical actions following the failure of one adequate
course of an … Fifteen studies
(18 publications)28,29,35-37,44,54,57,58,61-63,68,69,72,74,76,78
determined failure … What is the range of recommended
clinical actions following the failure of one adequate
course of SSRI … Medication
augmentation after the failure of SSRIs for depression. … Bupropion-
SR, sertraline, or venlafaxine-XR after failure of SSRIs
for depression.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/undescended-testicle_disposition-comments.pdf
December 11, 2012 - I believe failure to mention or discuss this fact is detrimental for
the ability to assess the effectiveness … Failure to at least address this controversy is a
determent to the synopsis. … Failure to at least address this controversy is a
determent to the synopsis. … Peer Reviewer #5 Discussion-
Conclusion
As noted above failure to address the cost of diagnostic studies … Peer Reviewer #5 Discussion-
Conclusion
As noted above failure of the authors to address ascent of
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-disease-testing_research-protocol.pdf
January 15, 2015 - outcomes include prevention of myocardial infarction (MI), premature mortality,
and congestive heart failure … Consideration of medical-legal
questions related to use or failure to use testing is beyond the scope … o Stroke
o Death
o Hospitalization for cardiovascular events (acute coronary syndrome, heart failure … • Stroke
• Death
• Cardiovascular hospitalization for acute
coronary syndrome, heart failure, … For these studies, only
the following hard clinical outcomes
will be evaluated: MI, heart failure,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/pneumonia-antibiotic-treatment_disposition-comments.pdf
November 24, 2014 - have higher minimum inhibitory
concentrations (MICs) to vancomycin that may increase
the clinical failure … in Table B, which
demonstrated significantly better (p <0.001) outcomes,
defined as lower clinical failure … The definitions used in each of the
studies for both clinical response and “treatment failure”
should … We have added clinical response and
treatment failure definitions to the KQ1 and KQ2 summary
tables … For certain patient-centered outcomes, such
as clinical response and treatment failure not otherwise
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/telehealth_disposition-comments.pdf
June 30, 2016 - MANAGEMENT
Remote Monitoring /or Heart
Failure: Study Size 50 patients
Flagstaff Medical Center … found
that through implementing a
remote heart failure monitoring
solution for the 6 months prior … Brian
Scarpelli,
Scarpelli
Coalition
General
Comments
Remote Patient Monitoring o/
Heart Failure … [Telemonitoring or structured
telephone support programmes
for patients with chronic heart
failure … Patients – Dignity Health
o Telemedical Support in
Patients with Chronic Heart
Failure: Experience
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-237-evidence-summary-palliative-care-ambulatory.pdf
February 01, 2021 - care for adults with serious life-threatening chronic illness
or conditions (e.g., advanced heart failure … have included triggers together with shared decision-
making tools for primary care and advanced heart failure
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-treatment-ssri_surveillance.pdf
January 01, 2013 - differences may have been related to the
longer trial duration as subjects were
randomized after failure … The effects of baseline severity,
previous treatment failure, age, gender, and
race were not sufficiently … What is the range of recommended clinical actions following the failure of one adequate course of SSRI … The
effects
of
baseline
severity,
previous
treatment
failure,
age,
gender … What is the range of recommended clinical actions following the failure of one adequate course of SSRI
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update_disposition-comments.pdf
October 07, 2011 - The indication in Table 1, page 23, Candesartan, column 3 for heart
failure is incomplete. … Please add, “… reduce cardiovascular death
and to reduce heart failure hospitalizations” to be consistent … The recommended dosing for heart failure was omitted from Table 1,
column 4. … Please consider adding the following: The recommended
initial dose for treating heart failure is 4 mg … hypertension, ischemic heart disease,
congestive heart failure, or nephropathy);
however all have examined
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - Peer Reviewer 4 KQ6
(incidence
of pump
Failure)
Lastly, many of the articles with good data on efficacy … Overall, if you leave this section
in, I would simply call it pump malfunction, rather than failure. … Uncontrolled case series were included only
for the outcomes of pump failure. … think the
RCT evidence should be included and not
non-comparative for outcomes other than of
pump failure … studies (case series, mostly) had preterm
contractions but were probably not in labor- hence their failure