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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
January 01, 2011 - Determine the Most Important Factors that May Affect Applicability
Identify potential factors. … The PICOS is a useful way of organizing factors that may affect
applicability. … Foremost are any factors that have
been associated with differences in treatment outcomes. … These factors should be identified a priori and stated in the protocol which
factors will be captured … Factors that can affect the
external validity of randomised controlled
trials.
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/renal-mass-and-localized-renal-cancer-the-following-questions-are-recommended-to-address-the-healthcare-tests-andor-treatments-this-program-should-consider-what-indicators-can-be-used-to-predict-malignancy-andor-aggressivenes
October 24, 2013 - Imaging Modality (US or CT/MRI Guided)
Factors influencing success (Tumor factors (tumor diameter, … cystic lesions, necrosis, location, depth), Patient factors (anticoagulation), operator)
Complication … Additional factors may include low physical activity, increased alcohol consumption, occupational exposure … Genetic factors and their interaction with environmental exposures are also thought to influence risk … While a direct cause has not been identified, there are several risk factors that have been shown to
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effectivehealthcare.ahrq.gov/products/worker-health/research-protocol
May 26, 2015 - Third, many contextual factors affect worker health; these include, for instance, health care coverage … These factors have not been widely considered as a modifier of intervention effectiveness. … Contextual factors may include (but are not limited to) the following: legal-regulatory environment ( … factors that may influence the effectiveness of interventions. … Some factors identified a priori that may limit the applicability of evidence include the following:
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/opioids-oa-protocol.pdf
June 29, 2019 - We plan to develop a framework to conceptualize and characterize the multiple factors that
interact … for opioid-related events among all older adults and risk factors for harm
among opioid users. … Underlying patient factors, such as fall risk, cognitive impairment, frailty, liver
disease, etc.
b. … Medication factors (opioid dosing and preparation; co-prescribing; etc.)
c. … Environmental factors (presence of a caregiver, etc.)
3.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-risk-reduction_research.pdf
October 25, 2010 - (3) Influencing factors—understanding influences such as health system factors,
communication, education … C1: What factors magnify or reduce
risk? … C1: What factors magnify or reduce risk? … C1: What factors magnify or
reduce risk? … (3) Influencing factors—understanding influences such as health system factors,
communication, education
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-genetic.ppt
June 01, 2012 - Key factors specifically affecting hereditary genetic tests need to be taken into account. … with using known factors alone. … ; such factors are useful when assessing analytic validity. … with using the known factors alone. … , and genetic tests should be evaluated in context with known risk factors such as these.
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effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-genetic.ppt
June 01, 2012 - Key factors specifically affecting hereditary genetic tests need to be taken into account. … with using known factors alone. … ; such factors are useful when assessing analytic validity. … with using the known factors alone. … , and genetic tests should be evaluated in context with known risk factors such as these.
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effectivehealthcare.ahrq.gov/products/cognitive-decline/research-protocol
March 23, 2016 - A number of reviews have assessed the evidence linking risk factors and protective factors to Alzheimer's … Nonmodifiable risk factors include age, sex, race/ethnicity, and family history. … Modifiable risk or protective factors may include diet, physical activity, education and intellectual … as protective factors (Table 1). … Genetic factors (i.e., ApoE status) have been shown to modify the degree to which risk factors and interventions
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0068_01-30-2009.pdf
January 01, 2009 - factor (RF) testing in children < 18 years of age and the evidence
regarding demographic or clinical factors … b) What is the evidence that demographic and clinical factors modify accuracy?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cognitive-decline_research-protocol.pdf
March 22, 2016 - A number of reviews have assessed the evidence linking risk factors and
protective factors to Alzheimer … Nonmodifiable risk factors include
age, sex, race/ethnicity, and family history. … Interventions have
been developed to address chronic disease status, modifiable risk factors as well … as
protective factors (Table 1). … Genetic factors (i.e., ApoE
status) have been shown to modify the degree to which risk factors and interventions
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-1.pdf
July 01, 2019 - 2
• Many factors must be considered when deciding whether to
combine studies in meta-analysis:
► Clinical … factors
► Methodological factors
► Statistical factors
• Studies must be reasonably similar to be pooled … and Methodological Heterogeneity
describe the variations in the population, intervention and study
factors … Statistical heterogeneity is discussed later
• A pooling decision tree guides consideration of these factors
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cad-women-treatment-future_research.pdf
February 01, 2013 - of age) or clinical factors (risk stratification or diabetes). … of age) or clinical factors (risk stratification or diabetes). … ; coronary disease risk
factors; angiography-specific factors; and hospital characteristics). … ”[MeSH Terms] OR (“sex”[All Fields]
AND “factors”[All Fields]) OR “sex factors”[All Fields]
#4 randomized … "[MeSH Terms] OR ("sex"[All Fields] AND
"factors"[All Fields]) OR "sex factors"[All Fields] OR gender
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-seniors-pneumonia_research.pdf
May 01, 2008 - Ascertainment of Potential Confounding Factors
Potential confounding factors were ascertained based … These are listed
in Tables 1 and 2, and included demographic factors, diagnoses ever recorded in the … Risk factors for
community-acquired pneumonia in adults: a
population-based case-control study. … Risk factors for community-
acquired pneumonia diagnosed upon hospital
admission. … Ascertainment of Potential Confounding Factors
2.7. Statistical Analysis
3. Results
3.1.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/worker-health_research-protocol.pdf
May 26, 2015 - mortality, morbidity, and
considerable financial and social costs.1-3 At the same time, modifiable risk factors … These factors have not
been widely considered as a modifier of intervention effectiveness. … What contextual factors have been identified as potential modifiers of effectiveness in
studies of … Contextual factors may include (but are not limited to) the following: legal-
regulatory environment … factors
that may influence the effectiveness of interventions.
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effectivehealthcare.ahrq.gov/sites/default/files/tech-brief-37-opiod-use-adults-comments.pdf
November 03, 2020 - Throughout, we discuss
“independent” variables/factors. … The factors most
commonly evaluated included demographic
factors, comorbidities, medication factors … Findings p. 39 – The Grigora study is a study of county
level risk factors not individual risk factors … This is also true for
factors associated with harms. … Street drugs
become an attractive distraction from such
factors.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancer-key-questions.pdf
January 01, 2020 - KQ3: Does treatment effectiveness vary by subgroup (high risk factors [i.e.., environmental and
occupational … /lifestyle factors], comorbidities [i.e., history of ulcers, Epstein-Barr virus, and other non-
cancer … -
KQ2: Tx effectiveness vary by cancer variables
KQ3: Tx effectiveness vary by subgroup (risk
factors
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/postpartum-care-one-year-protocol-amendment.pdf
April 25, 2022 - than 60 percent of pregnancy-related deaths are considered preventable.3, 5 Various
interdependent factors … have been implicated in causing deaths: systems of care factors (e.g., lack of
coordination among providers … ), provider factors (e.g., misdiagnoses, ineffective treatment), and patient
and family factors (e.g … These factors play a particularly
important role in the postpartum period, during which access to care … Given this
confluence of factors, up to half of postpartum individuals in the U.S. do not receive routine
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rotator-cuff-tears-future_research.pdf
February 01, 2013 - • Surgeon factors: What surgeon factors are associated with better operative repair and/or
better … • Patient factors: Which factors should be collected at baseline across all studies?
b. … • Psychosocial factors: How do factors such as depression, socioeconomic status,
motivation/self-efficacy … What patient factors matter? … • Patient factors: Which factors should be collected at baseline across all studies?
b.
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effectivehealthcare.ahrq.gov/sites/default/files/it-architecture-for-post-marketing-surveillance-arizona-cert.pdf
September 01, 2007 - We
define the key requirements of such a monitoring and reporting system, identify the critical
factors … We analyze each of these factors and identify the critical elements of the community
pharmacy based … Critical Success Factors
5.1 Factors Influencing Pharmacy Participation
The successful adoption and … of instruments to validate the hypothesized critical success factors. … Critical Success Factors
5.1 Factors Influencing Pharmacy Participation
6. Limitations
7.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medicine-safety-call-center_research.pdf
September 01, 2007 - We
define the key requirements of such a monitoring and reporting system, identify the critical
factors … We analyze each of these factors and identify the critical elements of the community
pharmacy based … Critical Success Factors
5.1 Factors Influencing Pharmacy Participation
The successful adoption and … of instruments to validate the hypothesized critical success factors. … Critical Success Factors
5.1 Factors Influencing Pharmacy Participation
6. Limitations
7.