-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/disparities-quality-improvement_executive.pdf
August 01, 2012 - One study of cardiovascular risk factor modification
showed no meaningful reduction in health disparities … Cardiovascular Disease
Studies of CAD risk factor control included men with
CAD risk factors at clinical … The interventions for CAD risk factor control included
intensive patient education and self-management … For studies of cardiovascular risk factor control, outcomes
consisted of intermediate clinical variables … Responses of black and white males to
the special intervention program of the Multiple Risk Factor
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-update_research-protocol.pdf
May 15, 2017 - Rates of RA development are increased in monozygotic
twins, implicating genetics as a contributing factor … disease activity remains moderate or high, double or triple combination
DMARDs or a tumor necrosis factor … Food and Drug
Administration; RA = rheumatoid arthritis; TNF = tumor necrosis factor; ts = targeted … disease-modifying antirheumatic drug; KQ = Key Question; RA =
rheumatoid arthritis; TNF = tumor necrosis factor … rheumatoid arthritis; RCT = randomized controlled trial; SR = systematic review; TNF = tumor
necrosis factor
-
effectivehealthcare.ahrq.gov/sites/default/files/s66.pdf
October 01, 2007 - These drugs include tumor necrosis factor antagonists (anti-
TNF) and an interleukin-1 antagonist (anti-IL … Anti-Tumor Ne-
crosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy
Study Group. … Adalimumab, a fully
human anti-tumor necrosis factor alpha monoclonal antibody, for the
treatment of … Eligibility of patients in routine care for major
clinical trials of anti-tumor necrosis factor alpha … Tumor necrosis factor inhibitors for rheumatoid
arthritis. N Engl J Med. 2006;355:704–712.
42.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-pancreas_research-protocol.pdf
August 09, 2013 - or tumor
characteristic
Another test: Effect of
patient factor or tumor
characteristic
Staging … FNA
• Sedation-related effects of EUS-FNA
(e.g., nausea, vomiting)
3a P1 or P2 or
P3
Patient factor … Comparator patient
factor
See the list of harms for KQ 3
3b P1 or P2 or
P3
Same list as KQ 1a … Source: www.effectivehealthcare.ahrq.gov
Published online: August 9, 2013
9
An important factor … Although this factor will not be addressed formally in the review as a KQ, we plan
to collect and provide
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-future-value-of-information_research.pdf
June 01, 2011 - Another factor that
should be considered is the likelihood that relevant information may be imperfectly … In other cases, a factor is considered, but without much
rigorous analysis. … VOI in Millions ICER-Trial £11 ICER-Trial ICER-Trial ICER-Trial $46 $308,000 £1 $64
Applied scale factor … for population at
risk* - 5.01 - - - 1.00 1.00 5.01 5.01
Applied scale factor for time horizon … for
population at risk* 1.0 - - - 13975§ 1 19 19 -
Applied scale factor for time
horizon 1 - - -
-
effectivehealthcare.ahrq.gov/sites/default/files/s81.pdf
October 01, 2007 - Female sex is an independent risk factor for bleeding on
anticoagulation.24 Codes for complications and … The model would overestimate the true ADE rate by
a factor of 8, but the crude rate of predicted ADEs … A very low PPV would
require a high discount factor of nearly 97% to estimate the
rate of drug-induced … This high discount factor and
the lack of clinically specific markers for delirium decrease
the likelihood
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - would be a trial in which randomized assignment to treatment groups
would be stratified by predictive factor … level or patients were randomized to
receive treatment guided by predictive factor or not. … adequately powered
stratified randomization would allow valid inferences of treatment by
predictive factor … of two treatments, whereas single-arm studies can only assess the
association between predictive factor
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/misuse-prescription-protocol-amendment.pdf
November 26, 2024 - Quality
In Prognosis Studies (QUIPS) tool13 which covers study participation, attrition,
prognostic factor … Judging the quality of evidence in reviews of
prognostic factor research: adapting the GRADE framework
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease-future_research.pdf
July 01, 2016 - although use of these medications was not
routine until the 1990s.4 The first biologic tumor necrosis factor … Stelara)†
0 1
TNF = tumor necrosis factor.
† Stakeholder provided comparison. … 0
Other: TNF-alpha inhibitor versus new treatment (that is
safer)†
0 1
TNF = tumor necrosis factor … Stelara)†
0 1
TNF: Tumor necrosis factor.
† Stakeholder provided comparison. … 0
Other: TNF-alpha inhibitor versus new treatment (that is
safer)†
0 1
TNF = tumor necrosis factor
-
effectivehealthcare.ahrq.gov/health-topics/rh-incompatibility
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypothyroidism-hyperthyroidism-screening-treatment_executive.pdf
October 01, 2011 - Subclinical thyroid dysfunction has
been shown to be a risk factor for the later
development of overt … In
addition, a high TSH level may be a risk
factor for coronary events, elevated
cholesterol levels, … and increased rates of
congestive heart failure, while a low TSH
level is a risk factor for atrial fibrillation
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-topics_methods.pdf
July 01, 2012 - 200217
FDG = fluorodeoxyglucose; FFDM = full-field digital mammography; HER2 = human epidermal growth factor … Technology Evaluation Center, 2002.14
The second example concerns use of the human epidermal growth factor … amplification assay to select patients for HER2-targeted therapy*
HER2 = human epidermal growth factor
-
effectivehealthcare.ahrq.gov/sites/default/files/data-extraction.ppt
January 01, 2009 - Study types include randomized trial, observational study, diagnostic test study, prognostic factor study … extracted, which may be a randomized trial, an observational study, a diagnostic test study, a prognostic factor … will be more objective (especially in their quality assessment) if they are undistracted by the impact factor
-
effectivehealthcare.ahrq.gov/sites/default/files/pulmonary-horizon-scan-high-impact-1512.pdf
December 01, 2015 - tyrosine kinase inhibitor that targets the
intracellular signaling of multiple proangiogenic growth factor … receptor 2
(VEGFR2), fibroblast growth factor receptor (FGFR), and platelet-derived growth factor … Esbriet®) is a synthetic pyridone analogue reported to inhibit
the synthesis of transforming growth factor … receptor kinase
activity of vascular endothelial growth factor receptor 2 (VEGFR2), fibroblast growth … factor
receptor (FGFR), and platelet-derived growth factor receptor (PDGFR).
-
effectivehealthcare.ahrq.gov/sites/default/files/zikmund.pdf
May 29, 2025 - • Enters risk factor info:
o BP, weight, height, cholesterol, etc.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-cancer-survivorship-protocol.pdf
June 01, 2020 - studies may report associations with
participant characteristics, e.g., reporting correlations
with a factor … AND (“inequit*” OR “disparit*” OR
“inequal*”)) OR ((“social*” OR “sociolog*” OR “sociology*”) AND (“factor … disparity OR disparities OR inequality OR inequalities)) OR ((social OR sociological
OR sociology) AND (factor
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
March 10, 2010 - I believe that older age at first birth should be added as
a risk factor for breast cancer. … rating was downgraded
because some women in the trial continued to use estrogen--an
important risk factor … Age is an important factor
in considering this risk benefit ratio.
2. … Factor 5 Leiden. It is not clear why it was marked as "wrong
population."
2. … There's not much literature available on this but it
might be mentioned, as a limiting factor of the
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/treatment-resistant-depression_disposition-comments.pdf
September 01, 2011 - program, we
have reported clinical outcomes for specific symptom subtypes
represented by standard factor … compared to the sham
TMS treatment group at both the week 4 and week 6 outcome time
points on the Factor … Factor Score, and the Psychomotor Retardation
Factor Score. … There was no difference on the Sleep Factor Score,
indicating that TMS does not exert a soporific effect … Symptom
subtypes represented by standard factor
scores measured
Berman, (2000) This study in included
-
effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
June 01, 2015 - Additionally, corticosteroids and tumor necrosis factor (TNF)-alpha inhibitors may
also be prescribed … Elevated serum uric
acid (sUA) levels are thought to be the most important risk factor for developing … and Allopurinol-Refractory Gout
Key Facts: Hyperuricemia is believed to be the most important risk factor … Allopurinol-Refractory Gout
Unmet need: Hyperuricemia is thought to be the most important risk factor … not respond adequately to NSAIDs, disease-
modifying anti-rheumatic drugs (DMARDs) or tumor necrosis factor
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
March 11, 2010 - Executive summary The term “rate” implies a time factor. What is it? … We are aware that “rate” implies a time factor in
epidemiological literature, but the literature on … to raise in this section is that a history of
previous benign breast biopsy is a significant risk factor … Prevention paper, Ashbeck et al. demonstrate that
a history of previous benign breast biopsy is not a
risk factor