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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
March 10, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … It is unclear, on first
reading, how the conclusions as to strength of evidence were
reached. … One
should not reach conclusions in the absence of a systematic review
of the evidence. … I
agree that the evidence is low. … in favor of Treatment A is
stronger than evidence in favor of Treatment B.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting_research-protocol.pdf
August 19, 2011 - Evidence-based Practice Center Systematic Review Protocol
1
Evidence-based Practice Center Systematic … Angiographic evidence of
stenosis is usually not detected until the plaque approaches 40 to 50 percent … Searching for the Evidence: Literature Search Strategies for Identification of
Relevant Studies To … We will assess the precision (precise or imprecise) of the evidence based on the degree of
certainty … As directed by the AHRQ Methods Guide, we will assign four possible grades for strength of
evidence
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
February 10, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Grading the Evidence for Each Key Question
We will grade the strength of evidence for primary outcomes … Strength of evidence grades and definitions
Grade Definition
High High confidence that the evidence … Moderate Moderate confidence that the evidence reflects the true effect. … Low Low confidence that the evidence reflects the true effect.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
January 10, 2012 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Strength of evidence rating
Grade Definition
High There is high confidence that the evidence reflects … Moderate Moderate confidence that the evidence reflects the true effect. … Low Low confidence that the evidence reflects the true effect. … Data required to
evaluate these domains will be extracted into evidence tables.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
June 01, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … review evidence for effectiveness in selected clinical settings”. … The report follows the strength of evidence
guidelines provided to the Evidence-based Practice Centers … the lack of
evidence supporting particular practices. … The report is indeed limited by the available evidence.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … (Prepared by the
University of Ottawa Evidence-based Practice Center under Contract No. … We stand by our grading
of the strength of evidence. … Our conclusions are based on evidence, its
strength and applicability. … evidence reflects a true
effect.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: February 19, 2010
1
Evidence-based Practice Center Systematic Review Protocol … view the consequences of
experiencing an ischemic stroke as being worse than death.9 Additionally, evidence … Searching for the Evidence: Literature Search Strategies for
Identification of Relevant Studies to … Grading the Evidence for Each Key Question
This is not applicable for technical briefs.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: November 22, 2011
1
Evidence-based Practice Center Systematic Review Protocol … One of the reviews found evidence of “publication bias” and concluded
that the evidence “does not indicate … We will assess directness of the evidence (“direct” vs. … Finally, we will rate the body of evidence on the basis of four strength of evidence
levels: high,
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
December 09, 2009 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: December 9, 2009
Evidence-based Practice Center Systematic Review Protocol … included in the
report only if there is lack of adequate higher quality evidence. … Appendix A outlines the most appropriate evidence and sources
of evidence searched for these questions … Grading the Body of Evidence
Where there are three or more studies, we will grade the body of evidence
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
March 14, 2012 - of the best available evidence
addressing KQs 1-4 by adapting an evidence grading scheme recommended … grading schemes are based on GRADE.26 We
will apply evidence grades to the bodies of evidence about … We will classify evidence pertaining to the KQs into four basic categories: 1) “high” strength
of evidence … (evidence is
unavailable).26
G. … Chapter 7: grading a body of evidence on
diagnostic tests.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
March 11, 2010 - The low quality of the evidence precludes an
evidence-based estimate of the size of effect. … Methods The grading of strength of evidence is unclear to me. … Methods A description on strength of evidence should be added. … Results Add strength of evidence ratings to Key Question 3. … For
this reason we did not rate the strength of the
evidence nor did we draw any formal evidence-
based
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - Evidence-based Practice Center Systematic Review Protocol
1
Source: www.effectivehealthcare.ahrq.gov … Published Online: September 2, 2011
Evidence-based Practice Center Systematic Review Protocol … Data Synthesis
Prepare Evidence Tables
We will enter data into evidence tables, using predetermined … Grading the Evidence for Each Key Question
Assess the Strength of Evidence
We will also use … The overall strength of evidence will be graded as “high” (indicating high confidence that the
evidence
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cystic-fibrosis-hgh_research-protocol.pdf
August 22, 2008 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: January 22, 2010 1
Evidence-based Practice Center Systematic Review … Grading the Evidence for Each Key Question
As it meets AHRQ CER recommendations, strength of evidence … Evidence Analysis Manual : Adapted for Dietary
Guidelines 2010 Nutrition Evidence Library – USDA. … GRADE handbook for grading quality of
evidence and strength of recommendation.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/therapies-for-autism-spectrum-disorder-2-9-2010.pdf
January 01, 2010 - Published Online: December 7, 2009
1
Evidence-based Practice Center Systematic Review Protocol … We
will record quality grades in the evidence tables.
E. … Data Synthesis
Prepare evidence tables. … Grading the Evidence for Each Key Question
Quality grading. … Evidence-based comprehensive treatments for early autism.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
August 10, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: August 10, 2010
Evidence-based Practice Center Systematic Review Protocol … In the
past 10 years clinicians have been applying evidence from studies of school-age
children with … Grading the Evidence for Each Key Question
We will assess the overall strength of the body of the evidence … Evidence Report/Technology Assessment No.11.
AHRQ Publication No. 00-E005.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/autism-adolescents_research-protocol.pdf
March 29, 2011 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Preparing evidence tables. … Grading the Evidence for Each Key Question
Assessing the strength of evidence. … The overall strength of evidence will be graded as “high” (indicating high confidence that the
evidence … Evidence-based Practice Center systematic review protocol.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/insulin-blood-sugar-2010_research-protocol.pdf
January 01, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: June 2, 2011
Evidence-based Practice Center Systematic Review Protocol
Project … Searching for the Evidence: Literature Search Strategies for Identification of
Relevant Studies To … of evidence based on the
quantity, quality, and consistency of the best available evidence, addressing … apply
evidence grades to the bodies of evidence about each intervention comparison for each outcome
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/stem-cell-children_research-protocol.pdf
November 01, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: August 5, 2010
Evidence-based Practice Center Systematic Review Protocol … the
evidence is based on case series and case
report data. … a second reviewer will perform accuracy checks on the evidence
tables. … GRADE: an emerging consensus on rating
quality of evidence and strength of recommendations.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/high-cholestorol-medications_disposition-comments.pdf
March 10, 2010 - A way of phrasing an evidence-based conclusion might be "In summary,
the available evidence supporting … b) "…safety and efficacy are established with evidence." … or they are not, "evidence" does not change that. … By this I mean if
you look at the surogate outcomes with evidence and the outcomes
without evidence … If it has evidence, it is then
presented.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/tinnitus_research-protocol.pdf
February 22, 2012 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: February 22, 2012
Evidence-based Practice Center Systematic Review Protocol … All team members will share the task of initially entering information into the evidence table. … Grading the Evidence for Each Key Question
We will assess the overall strength of evidence for … Directness of the evidence (concerns whether the evidence being assessed reflects a single, direct
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