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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
July 18, 2011 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … of
evidence. … Grading the Evidence for Each Key Question
We will evaluate the overall strength of the evidence … The overall
strength of evidence will be graded as “high” (indicating high confidence that the evidence … Combination of direct and indirect evidence in mixed treatment comparisons.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/procalcitonin_research-protocol.pdf
September 08, 2011 - Evidence Tables-Templates for evidence tables will be created in Microsoft
Access®. … that the evidence reflects the true effect. … Low-Low confidence that the evidence reflects the true effect. … Evidence Report/Technology Assessment No. 172. … evidence.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/medication-adherence-interventions_research-protocol.pdf
August 18, 2011 - Grading the Evidence for Each Key Question. … We will grade the strength of evidence based on the guidance established by the Evidence-based
Practice … Table 5 describes the grades of evidence that can be assigned. … that the evidence reflects the true effect. … Adherence to Long Term Therapies:
Evidence for Action.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/inguinal-hernia_research-protocol.pdf
August 15, 2011 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … The evidence review will
specifically examine evidence on the association between surgical experience … boldface, along with the rating of
the evidence supporting that conclusion. … Assessing the Applicability of the Evidence for Each Key Question
The applicability of the evidence … A system for rating the stability and strength of medical evidence.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ongoing-studies-evidence_research.pdf
December 01, 2010 - Evidence-based Practice Center Future Research Needs
Methods Future Research Needs Report
Number … Finding Evidence on
Ongoing Studies. Methods Future Research Needs Report No. 1. … narrative, list of gaps based on available evidence). … The authors of evidence-based reports have to list future research
needs based upon available evidence … Evidence of underpublication of
registered clinical trials in oncology.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … (Prepared by the Duke Evidence-based Practice
Center under Contract No. 290-02-0025.) … Rating
the body of evidence is defined, but the reasons that evidence was
rated low for some outcomes … For many of the included biologics no evidence was available at
all. … , which unfortunately is the strength
of the majority of the evidence reported.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/musculoskeletal-complaints-tests-children_research-protocol.pdf
September 29, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: September 29, 2010
Evidence-based Practice Center Systematic Review Protocol … Though there is good evidence regarding the
performance characteristics and use of ANA, RF, and CCP … Grading the Evidence
For this diagnostic test accuracy review, evidence will be graded for KQ.3, KQ … The directness of evidence will also be assessed.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/juvenile-arthritis-dmards_research-protocol.pdf
March 09, 2010 - Published Online: March 09, 2010
1
Evidence-based Practice Center Systematic Review Protocol … Grading the Evidence for Each Key Question
The strength of evidence for each key question will be assessed … Evidence Report/Technology Assessment No. 94 (Prepared by Tufts-New
England Medical Center Evidence-based … Available
at:http://www.ahrq.gov/downloads/pub/evidence/pdf/o3cardio/o3cardio.pdf. … Evidence Report/Technology Assessment No. 167 (Prepared by the Duke University
Evidence-based Practice
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-disease-ace-inhibitor-arb-disposition.pdf
March 10, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … It is unclear, on first
reading, how the conclusions as to strength of evidence were
reached. … One
should not reach conclusions in the absence of a systematic review
of the evidence. … I
agree that the evidence is low. … in favor of Treatment A is
stronger than evidence in favor of Treatment B.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting_research-protocol.pdf
August 19, 2011 - Evidence-based Practice Center Systematic Review Protocol
1
Evidence-based Practice Center Systematic … Angiographic evidence of
stenosis is usually not detected until the plaque approaches 40 to 50 percent … Searching for the Evidence: Literature Search Strategies for Identification of
Relevant Studies To … We will assess the precision (precise or imprecise) of the evidence based on the degree of
certainty … As directed by the AHRQ Methods Guide, we will assign four possible grades for strength of
evidence
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/asthma-treatment_research-protocol.pdf
February 10, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Grading the Evidence for Each Key Question
We will grade the strength of evidence for primary outcomes … Strength of evidence grades and definitions
Grade Definition
High High confidence that the evidence … Moderate Moderate confidence that the evidence reflects the true effect. … Low Low confidence that the evidence reflects the true effect.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/psoriasis-chronic_research-protocol.pdf
January 10, 2012 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Strength of evidence rating
Grade Definition
High There is high confidence that the evidence reflects … Moderate Moderate confidence that the evidence reflects the true effect. … Low Low confidence that the evidence reflects the true effect. … Data required to
evaluate these domains will be extracted into evidence tables.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
June 01, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … review evidence for effectiveness in selected clinical settings”. … The report follows the strength of evidence
guidelines provided to the Evidence-based Practice Centers … the lack of
evidence supporting particular practices. … The report is indeed limited by the available evidence.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/preterm-birth-terbutaline-pump_disposition-comments.pdf
September 01, 2011 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … (Prepared by the
University of Ottawa Evidence-based Practice Center under Contract No. … We stand by our grading
of the strength of evidence. … Our conclusions are based on evidence, its
strength and applicability. … evidence reflects a true
effect.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ischemic-stroke-treatment_research-protocol.pdf
February 19, 2010 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: February 19, 2010
1
Evidence-based Practice Center Systematic Review Protocol … view the consequences of
experiencing an ischemic stroke as being worse than death.9 Additionally, evidence … Searching for the Evidence: Literature Search Strategies for
Identification of Relevant Studies to … Grading the Evidence for Each Key Question
This is not applicable for technical briefs.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antiplatelet-treatment_research-protocol.pdf
November 22, 2011 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: November 22, 2011
1
Evidence-based Practice Center Systematic Review Protocol … One of the reviews found evidence of “publication bias” and concluded
that the evidence “does not indicate … We will assess directness of the evidence (“direct” vs. … Finally, we will rate the body of evidence on the basis of four strength of evidence
levels: high,
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_research-protocol.pdf
December 09, 2009 - Evidence-based Practice Center Systematic Review Protocol
Source: www.effectivehealthcare.ahrq.gov … Published Online: December 9, 2009
Evidence-based Practice Center Systematic Review Protocol … included in the
report only if there is lack of adequate higher quality evidence. … Appendix A outlines the most appropriate evidence and sources
of evidence searched for these questions … Grading the Body of Evidence
Where there are three or more studies, we will grade the body of evidence
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
March 14, 2012 - of the best available evidence
addressing KQs 1-4 by adapting an evidence grading scheme recommended … grading schemes are based on GRADE.26 We
will apply evidence grades to the bodies of evidence about … We will classify evidence pertaining to the KQs into four basic categories: 1) “high” strength
of evidence … (evidence is
unavailable).26
G. … Chapter 7: grading a body of evidence on
diagnostic tests.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy_disposition-comments.pdf
March 11, 2010 - The low quality of the evidence precludes an
evidence-based estimate of the size of effect. … Methods The grading of strength of evidence is unclear to me. … Methods A description on strength of evidence should be added. … Results Add strength of evidence ratings to Key Question 3. … For
this reason we did not rate the strength of the
evidence nor did we draw any formal evidence-
based
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/undescended-testicle_research-protocol.pdf
September 02, 2011 - Evidence-based Practice Center Systematic Review Protocol
1
Source: www.effectivehealthcare.ahrq.gov … Published Online: September 2, 2011
Evidence-based Practice Center Systematic Review Protocol … Data Synthesis
Prepare Evidence Tables
We will enter data into evidence tables, using predetermined … Grading the Evidence for Each Key Question
Assess the Strength of Evidence
We will also use … The overall strength of evidence will be graded as “high” (indicating high confidence that the
evidence