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  1. effectivehealthcare.ahrq.gov/products/methods-balancing-harms-benefits/research
    February 13, 2014 - Evaluation of the Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular Events: A Comparison of Quantitative Approaches Research Report February 13, 2014 Web Version [NLM Site] Download Main Document PDF 342.5 KB People using assistive technology may not be able to fully access informat…
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/scarce-resources-protocol.pdf
    January 01, 2013 - 2012 AHRQ evidence review identified strategies for allocating medical resources in a mass casualty event
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gaps-pain-management.pdf
    January 01, 2023 - short-term adverse events versus nonopioid pharmacologic therapy for acute pain, including any adverse event … Pain during the week or month following the inciting event and persistent opioid use were rarely reported
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
    January 01, 2010 - resulted in release of two special FDA advisories in 2006,7,8 as well as subsequent studies refining event … In the rare event that a single ACC-NCDR® record could Effective Health Care Research Report Number … Death was the only event defined both during the index PCI procedure (using ACC-NCDR® information) … of repeat revascularization in our population (24%) may be due to not censoring patients after an event … Unadjusted and adjusted results from time-to-event analyses for prespecified endpoints.
  5. effectivehealthcare.ahrq.gov/products/headaches-pregnancy/protocol
    November 12, 2019 - or harm or harms or harmful or toxic or injurious or serious or fatal) AND (effect* or reaction* or event … or harm or harms or harmful or toxic or injurious or serious or fatal) AND (effect* or reaction* or event
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/headaches-pregnancy.pdf
    March 23, 2019 - harm or harms or harmful or toxic or injurious or serious or fatal) AND (effect* or reaction* or event … or harm or harms or harmful or toxic or injurious or serious or fatal) AND (effect* or reaction* or event
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/ace-inhibitor-arb-update-surveillance-160328.pdf
    March 28, 2016 - .$$ •$ May$reflect$low$event$rates$among$otherwise$healthy$patients$and$relatively$few$studies$ with … &ACEI&or&ARB)& $ Although$several$studies$collected$data$on$angioedema,$the$event$rates$were$very$low … $From$these,$38$ deaths$and$13$strokes$were$ reported.$$ •$ May$reflect$low$event$rates$ among$otherwise … &ACEI&or& ARB)& $ Although$several$studies$collected$data$ on$angioedema,$the$event$rates$were$
  8. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/renal-artery-stenosis_executive-2007.pdf
    January 01, 2007 - Layout 1 This report is an update to a Comparative Effectiveness Review on management strategies for renal artery stenosis (RAS) from October 2006. The systematic review included all studies of patients with atherosclerotic RAS (ARAS) that compared two or more interventions. It also reviewed recent prospective cohort…
  9. effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
    February 01, 2016 - found skeletal muscle relaxants for acute LBP to be associated with increased risk of any adverse event … Low One trial found no differences between ultrasound vs. sham ultrasound in risk of any adverse event
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/sodium-potassium_research-protocol.pdf
    April 18, 2017 - mortality o Stroke, coronary heart disease, myocardial infarction o Number of patients with any CVD event … study reports more than one outcome in this category, we will abstract data for only one type of event … disease mortality Stroke Coronary heart disease Myocardial infarction Number of patients with any CVD event … follow up: mean/median 24-h urinary excretion , status Outcomes: type and definition (e.g., any CVD event … intervention vs control e.g., RR (CI) % reaching prespecified BP goal CVD e.g., RR (CI) any CVD event
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
    May 01, 2013 - Nonfatal MI SOE=Insufficient 2 RCTs, 497 patients Inconclusive evidence due to low event rates in … Nonfatal stroke SOE=Insufficient 3 RCTs, 1932 patients Inconclusive evidence due to low event rates
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/anal-cancer-draft-report.pdf
    October 31, 2023 - One RCT (n=110) reported one grade 4 event in CRT vs zero grade 4 events in RT alone. … Insufficient Overall late harms 1; RCTs; n=310 5 events in 5FU + MMC arm vs. 1 event in 5FU arm … One RCT (n=682) reported grade 3 toxicity frequency of 2 events in MMC arm vs. 1 event in cisplatin … No significant difference was found in CR, progression-free or event-free survival between arms. … Neither NRSI reported comparisons for acute or late toxicity event rates. Table 25.
  13. effectivehealthcare.ahrq.gov/sites/default/files/arthritis-horizon-scan-high-impact-1506.pdf
    June 01, 2015 - , versus 55.7% given placebo; serious adverse event rates were 1.6%, 2.4% and 4.1%, respectively.5 … Similar adverse event rates were reported for secukinumab 75 mg (57.5%), 150 3 mg (62.5%), and … However, some experts were concerned about the adverse event rates reported.12,15 Some experts also … research expert noted concerns over renal adverse events, which could require additional adverse-event … in the pooled secukinumab group and 58.2% of patients in the placebo group reported an adverse event
  14. effectivehealthcare.ahrq.gov/products/colorectal-surgery-preparation/research-protocol
    March 26, 2013 - This cutoff is chosen to ensure that studies can estimate low event rates with adequate precision. … evaluate (and if statistical analyses are deemed appropriate, to estimate more precisely) the adverse event … Study-level or summary estimates of event rates will also be used to contextualize the relative effects … In the event of protocol amendments, the date of each amendment will be accompanied by a description
  15. effectivehealthcare.ahrq.gov/sites/default/files/cer-221-copd-evidence-summary.pdf
    October 01, 2019 - Evidence Summary: Pharmacologic and Nonpharmacologic Therapies in Adult Patients With Exacerbation of COPD Purpose of Review To evaluate the effectiveness and harms of pharmacologic and nonpharmacologic treatments for exacerbations of chronic obstructive pulmonary disease. Key Messages • Antibiotic therapy in…
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/administrative-data-validity_research.pdf
    January 01, 2007 - deemed the gold standard, this definition was used during the review process to validate each putative event
  17. effectivehealthcare.ahrq.gov/sites/default/files/upenn-final-report-2005-certs-ce-supplement.pdf
    January 01, 2005 - deemed the gold standard, this definition was used during the review process to validate each putative event
  18. effectivehealthcare.ahrq.gov/products/nonopioid-chronic-pain/protocol
    March 01, 2019 - or severity of pain, underlying pain condition, presence of medical and psychiatric comorbidities, event
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonopioid-pharm-chronic-pain-protocol.pdf
    February 01, 2019 - or severity of pain, underlying pain condition, presence of medical and psychiatric comorbidities, event
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hip-fracture-pain.ppt
    May 01, 2011 - AHRQ Publication No. 11-EHC022-EF http://effectivehealthcare.ahrq.gov/hippain.cfm Overall, adverse event … Adverse Events Influenced by Pain Management Interventions Overall, adverse event rates were similar

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