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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-annual-update2-appendices.pdf
January 16, 2023 - Any adverse event for high-THC versus placebo (short term, 1 to 6 months followup)
Abbreviations … ; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event. … ; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event. … ; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event. … ; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse
event.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/registries-guide_executive.pdf
April 01, 2007 - Adverse Event Detection,
Processing, and Reporting
The U.S. … Food and Drug Administration defines an
adverse event (AE) as any untoward medical
occurrence in a patient … AEs are categorized according to the
seriousness and, for drugs, the expectedness of the
event. … for all marketed
products is dependent on the principle of “becoming
aware,” collection of adverse event
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effectivehealthcare.ahrq.gov/products/antidepressants-update/research-protocol
July 13, 2011 - phases, it is considered part of the same depressive episode
Summary of Protocol Amendments
In the event
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/antidepressants-update_research-protocol.pdf
July 13, 2011 - Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/glucocorticoid-injections_clinician.pdf
June 01, 2016 - A Randomized Trial of Epidural Glucocorticoid Injections for Spinal Stenosis: A Brief Summary of Findings for Clinicians
A Randomized Trial of Epidural Glucocorticoid
Injections for Spinal Stenosis: A Brief Summary
of Findings for Clinicians
KEY CLINICAL ISSUE
What are the relative effectiveness and adverse effect…
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effectivehealthcare.ahrq.gov/sites/default/files/cer-229-opioid-treatments-chronic-pain-evidence-summary.pdf
April 01, 2020 - CER 229 Evidence Summary: Opioid Treatments for Chronic Pain
Purpose of Review
To assess the effectiveness and harms of opioid therapy
for chronic noncancer pain, alternative opioid dosing
strategies, and risk mitigation strategies
Key Messages
• Opioids are associated with small improvements
versus placebo in …
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/surveillance-report-1-nonopioid-treatments-chronic-pain.pdf
December 01, 2021 - • All drug classes: Withdrawal from treatment due to
adverse events (any adverse event, not specifically … nonsignificant increase in risk of
nausea with THC/CBD
No change in
conclusions
Abbreviations: AE=adverse event … with
increased risk of withdrawal versus placebo (2.1% vs. 0%, p>0.05).6
The most common adverse event
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effectivehealthcare.ahrq.gov/products/antipsychotics-adults/research
August 14, 2012 - Current Page Topic Timeline Dec. 16, 2009 Topic Initiated Dec. 1, 2010 Research Protocol Aug. 14, 2012 Systematic Review Mar. 30, 2015 Surveillance Report First-Generation Versus Second-Generation Antipsychotics in Adults: Comparative Effectiveness
Systematic Review Archived August 14, 2012 Web Version [NLM Site] …
-
effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/cer-250-cannabis-surveillance-report-3.pdf
May 01, 2022 - • Other key adverse event outcomes (i.e., psychosis, cannabis use disorder, cognitive
deficits) … ) Insufficient (1)
Abbreviations: CBD = cannabidiol; CBDV = cannabidivarin; SAE = serious adverse event … ; SOE = strength of evidence; THC =
tetrahydrocannabinol; WAE = withdrawal due to adverse event. … ; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event … ; SOE = strength of evidence; THC = tetrahydrocannabinol; WAE = withdrawal due to adverse event
-
effectivehealthcare.ahrq.gov/products/carioverter-difibrillators/abstract
April 14, 2010 - Real World Effectiveness of Implantable Cardioverter Defibrillators (ICDs) in Medicare Patients
Abstract Archived April 14, 2010
Topic Abstract
Background: Although ICDs provide meaningful prolongation of life for patients in clinical trials at high risk for sudden cardiac death (SCD), data are lack…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_overview.pdf
January 17, 2014 - Update Topic Brief CER 27 NSD FINAL_SJ final
Oral Diabetes Medications for Adults with Type 2 Diabetes
Nomination Summary Document
Results of Topic Selectio…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
March 26, 2013 - This cutoff is chosen to ensure that studies can estimate low event
rates with adequate precision.b … example, assuming the true incidence proportion is 0.01 (=1%) the probability of observing at least one event … evaluate (and if statistical analyses are
deemed appropriate, to estimate more precisely) the adverse event … Study-level or summary estimates of event rates will also be used to
contextualize the relative effects … In the event of protocol amendments, the date of each
amendment will be accompanied by a description
-
effectivehealthcare.ahrq.gov/sites/default/files/dyspnea-advanced-cancer-summary-1.pdf
November 01, 2020 - • Both nonpharmacological and pharmacological interventions led to adverse
event-related dropouts
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND_0334_08-04-2010.pdf
January 01, 2010 - Effective Health Care
Topic Number: 0285
Document Completion Date: 3-22-11
1
Results of Topic Selection Process & Next Steps
Pharmacogenetic testing for CYP2C19 variants for guiding antiplatelet treatment will go forward for
refinement as a systematic review. The scope of this topic, including p…
-
effectivehealthcare.ahrq.gov/products/antiplatelet-treatment/research
September 25, 2013 - Current Page Topic Timeline Aug. 4, 2010 Topic Suggestion Nov. 22, 2011 Research Protocol Sep. 25, 2013 Systematic Review Feb. 13, 2014 Disposition of Comments Report Testing of CYP2C19 Variants and Platelet Reactivity for Guiding Antiplatelet Treatment
Systematic Review Archived September 25, 2013 Web Version [NL…
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-202-bronchial-thermoplasty-asthma.pdf
December 01, 2017 - Effectiveness and Safety of Bronchial Thermoplasty in Management of Asthma: Evidence Summary
Comparative Effectiveness Review
Number 202
Effectiveness and Safety of Bronchial Thermoplasty in
Management of Asthma
Evidence Summary
Objectives and Rationale for Review
This report summarizes a systematic
review, “E…
-
effectivehealthcare.ahrq.gov/sites/default/files/moyer_eccs2012.pdf
January 01, 2012 - Slide 7: The
Mammography Firestorm
• This was a sentinel event in
the history of the U.S.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/schizophrenia-adult_research-protocol.pdf
September 23, 2016 - Contacting Authors: In the event that information regarding methods or results appear
to be omitted
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/epilepsy-medicine_research-protocol.pdf
February 01, 2008 - health
and adverse events (along with their definitions) will be collected if applicable including the
event … In the event that there is more than one newer antiepileptic drug being compared with an
older antiepileptic … separate trial) by dividing the older antiepileptic drug group equally
between the comparisons.44 In the event … referral or primary care
population)
Population Events rates markedly different
than in community
Event … Summary of Protocol Amendments
In the event of protocol amendments, the date of each amendment will
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/peripheral-artery-disease-pad-defined-as-peripheral-artery-disease-of-the-lower-extremities-1-does-aspirin-reduce-the-risk-of-adverse-cardiovascular-events-mi-stroke-cardiovascular-death-in-patients-with-pad-is-there-a-differ
January 20, 2011 - Home »
Get Involved »
Nominated Topics »
Topic Suggestion Description
Topic Suggestion Description
Date submitted: January 20, 2011
Download Topic Suggestion Disposition [PDF · 143.5 KB]
Briefly describe a specific question, or set of related questions, about a healt…