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effectivehealthcare-admin.ahrq.gov/products/diagnostic-errors-emergency/research
February 01, 2023 - Some of these patients suffer an adverse event because of the incorrect diagnosis (~2.0%), and some of … translates to about 1 in 18 ED patients receiving an incorrect diagnosis, 1 in 50 suffering an adverse event … United States that 7.4 million (5.7%) patients are misdiagnosed, 2.6 million (2.0%) suffer an adverse event … Estimated preventable adverse event rates were as follows: any harm severity (2.0%, 95% CI 1.0 to 3.6
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-250-cannabis-other-plant-based-treatments-evidence-summary_0.pdf
October 01, 2021 - • Other key adverse event outcomes (psychosis, cannabis use disorder, cognitive
deficits) and outcomes … ) Insufficient (1)
Abbreviations: CBD = cannabidiol; CBDV = cannabidivarin; SAE = serious adverse event … ; SOE = strength of evidence; THC =
tetrahydrocannabinol; WAE = withdrawal due to adverse event. … Understanding how the adverse
event profiles of cannabis products compare with other available treatments … In order to better understand the small to moderate improvements in pain, and
the complete adverse event
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effectivehealthcare-admin.ahrq.gov/products/diagnostic-errors-emergency-updated/research
August 01, 2023 - Some of these patients suffer an adverse event because of the incorrect diagnosis (~2.0%), and some of … translates to about 1 in 18 ED patients receiving an incorrect diagnosis, 1 in 50 suffering an adverse event … United States that 7.4 million (5.7%) patients are misdiagnosed, 2.6 million (2.0%) suffer an adverse event … Estimated preventable adverse event rates were as follows: any harm severity (2.0%, 95% CI 1.0 to 3.6
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-afib.pdf
November 15, 2018 - It
is possible within an EHR setting to identify that an event occurred, but it is difficult and often … not feasible to determine the cause of the event unless the event is recorded specifically as a
procedure … For other events, it is feasible to identify an event that occurs in a
specified time window after a … procedure or treatment, but the event is not linked specifically to
the procedure as a complication … In these cases, causality is assumed based on the nature of the
event and the timing.
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effectivehealthcare-admin.ahrq.gov/products/gout/research-2016
March 01, 2020 - Adverse Events Associated with Gout Diagnostic Methods
One new study identified one serious adverse event … after synovial fluid aspiration (septic arthritis 11 days post arthrocentesis, event rate 0.1%, 95% … CI 0, 0.34) and 11 nonserious adverse events (mostly mild pain following the procedure; event rate 1.4%
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
February 01, 2018 - Low-event-rate meta-analyses of clinical trials: implementing good practices. Stat Med. 2016. … dx.doi.org/10.1002/sim.6844
http://dx.doi.org/10.1002/sim.2528
• The Peto method performs best when event … overestimate confidence intervals in small studies with low heterogeneity
• Peto method
► Best when event … Low-event-rate meta-analyses of clinical trials: implementing good practices.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-1-app-F.xlsx
January 01, 2023 - Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for Any … Event (Numberator Intervention C, N Analyzed for Any Adverse Event (Denominator) Intervention C, % … With Any Adverse Event Intervention D, N of Any Adverse Event (Numberator Intervention D, N Analyzed … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … ) Intervention C, % With Serious Adverse Event Intervention D, N of Serious Adverse Event (Numerator)
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4-tables-E-1-E-4.xlsx
January 01, 2023 - Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for Any … Event (Numberator Intervention C, N Analyzed for Any Adverse Event (Denominator) Intervention C, % … With Any Adverse Event Intervention D, N of Any Adverse Event (Numberator Intervention D, N Analyzed … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … ) Intervention C, % With Serious Adverse Event Intervention D, N of Serious Adverse Event (Numerator)
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cannabis-2022-surv-rep-4-tables-F1-4.xlsx
January 01, 2022 - Adverse Event Intervention B, N of Any Adverse Event (Numerator) Intervention B, N Analyzed for Any … Event (Numerator) Intervention C, N Analyzed for Any Adverse Event (Denominator) Intervention C, % … With Any Adverse Event Intervention D, N of Any Adverse Event (Numerator) Intervention D, N Analyzed … A, % With Serious Adverse Event Intervention B, N of Serious Adverse Event (Numerator) Intervention … ) Intervention C, % With Serious Adverse Event Intervention D, N of Serious Adverse Event (Numerator)
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-selection-harms-systematic-reviews.pdf
February 01, 2018 - What is a Serious Adverse Event? … What is a Serious Adverse Event? … , not an adverse event. … is a failed treatment, not an adverse event. … What is a Serious Adverse Event? 2016.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/gerd-2005_executive.pdf
January 01, 2005 - Higher adverse event rates were described for PPIs
than for H2RAs or placebo. … PPIs (1 RCT): no direct
comparative adverse event data reported in this study; in surgical
group, 3.7% … the surgical group; 4.5% developed
dysphagia that persisted for > 3 months after surgery; adverse
event … There are no direct comparative adverse event data for endoscopic
vs. laparoscopic procedures.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-d-opioid-chronic-pain-surveillance-report-3.xlsx
September 30, 2015 - Abbreviations: AE = adverse event; BMI = body mass index; CI = confidence interval; COWS = Clinical Opiate … D
Any opioid-related event: 5.3% vs. 6.1% vs. 3.4% vs. 3.6%, p<0.0001
Suicide (fatal or nonfatal): 1.0% … 0.7% vs. 1.7%, p=0.0002
Other opioid-related harms: 3.2% vs. 3.8% vs. 4.6% vs. 1.9%, p<0.0001
Adverse event … HR 1.67 (95% CI 1.51 to 1.84)
Safety event hospitalizations
A vs. B vs. … B: Controls: (n=2,311), patients without an opioid-related adverse event, 1:1 matching based on age
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effectivehealthcare-admin.ahrq.gov/health-topics/suicide
April 10, 2025 - Often it's related to serious depression, alcohol or substance abuse , or a major stressful event.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/app-e-surv-rept-1-acute-pain.xlsx
September 21, 2022 - B
Any adverse event: 13.6% (11/81) vs. 18.6% (16/86) NR NR Fair
Abbreviations: CI = confidence interval … B
Any adverse event: 10.0% (6/60) vs. 18.6% (11/59), RR 0.54 (95% CI 0.21 to 1.36)
Nausea: 0.8% (1/60 … B
Any adverse event: 34% (26/76) vs. 9% (7/74), RR 3.62 (95% CI 1.67 to 7.82)
Dizziness: 7.9% (6/76) … B
Any adverse event: 11.6% (8/69) vs. 13.2% (9/68), p=0.57 NR Institutional grant Fair
Frants, 2021 … D
Any adverse event: 30.2% (62/205) vs. 46.2% (96/208) vs. 51.0% (105/206) vs. 23.2% (48/207)
Nausea:
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effectivehealthcare-admin.ahrq.gov/products/stroke-atrial-fibrillation/research
December 01, 2019 - switching between warfarin and novel oral anticoagulants or to stroke prevention after a hemorrhagic event … procedures, switching or bridging therapies, and when to start anticoagulation after a hemorrhagic event
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effectivehealthcare-admin.ahrq.gov/products/gestational-diabetes-screening-diagnosis/research-protocol
December 01, 2019 - with an adverse event. … We will count each event as if it corresponded to a unique individual. … Because an individual patient may experience more than one event during the course of the study, this … assumption may overestimate the number of patients that experience an adverse event. … In the event that studies cannot be pooled, evidence tables will be produced and a narrative summary
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/ptsd-adults-trauma-interventions_disposition-comments.pdf
April 02, 2013 - The studies included in
this review focused on those exposed to a
traumatic event who may be at risk … This
conceptualization of an adverse event is
consistent with how AEs are defined in
mental health … I suggest you might want to more clearly distinguish the source
event(s) from the aftermath. … We have replaced “a traumatic event” with
“psychological trauma” to reflect the fact that
trauma might … and PTSD; caused by the event and causing
PTSD.)
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effectivehealthcare-admin.ahrq.gov/products/COVID-19-pharmaceutical-treatments/rapid-research
March 01, 2024 - Serious adverse events, tocilizumab Serious Adverse Event Study n/N Intervention n/N Control Dose Risk … 7.69 Moderate/Unclear Stone, 2020 2/161 0/82 8 mg per kg RR 2.56; CI 0.12, 52.75 Low Thrombotic Event … RR 0.41; CI 0.11, 1.48 Low Serious adverse events, convalescent plasma Serious Adverse Event … First, if collection was passive (i.e., outpatients contacted researchers if they experienced an event … Secondly, if the authors reported the proportion of patients experiencing each event (e.g., rather than
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effectivehealthcare-admin.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - Harms
Across all classes, incidence of serious adverse
event (SAEs) was low. … ; SOE = strength of evidence; TCA = tricyclic antidepressant;
WAE = withdrawal due to adverse event … not applicable to drug); SAE = serious adverse event;
SOE = strength of evidence; WAE = withdrawal … event=overview.process&ApplNo=021014.
Accessed July 31, 2019.
8. … event=overview.
process&ApplNo=019872. Accessed July 31, 2019.
11.
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effectivehealthcare-admin.ahrq.gov/products/antidepressants-seniors-pneumonia/research
January 01, 2020 - The index date for cases was the date of the case event. … For persons with more than one case event, we included only the first event. … defined above), who had not yet experienced the relevant study outcome before the corresponding case's event … This is analogous to time-to-event analyses of cohort studies, and ensures the interpretability of the … An analysis of administrative data found that proximate clinical event ratios provided a systematic approach