-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
March 01, 2011 - or
thiazolidinediones.
7
Outcomes of Interest
Overall, few studies contained sufficient data on event … We recommend improvements in adverse event
and long-term outcome reporting, with predefined
outcomes … (continued)
Gastrointestinal Moderate Metformin was associated with twice as many GI adverse event rates
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
January 01, 2007 - Only one study reported an adverse event of
thrombocytopenia and leucopenia, making comparisons
between … cholecystitis compared with placebo in a pooled analysis.
data
NA FDA data were consistent with the adverse event
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
July 01, 2011 - No adverse event with potentially long-
term consequences was reported.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
May 01, 2010 - evaluate evidence of harm from rFVIIa in
noncomparative studies, we described the unadjusted
summary event … rates for mortality and thromboembolic
events from the noncomparative studies, as well as
event rates … Thromboembolic event risk differences
(rFVIIa minus usual care)
• There was no effect of rFVIIa on mortality … • rFVIIa use was associated with a higher
thromboembolic event rate (risk difference 0.053;
95 percent … and thromboembolic events could not be
evaluated due to limited reported events (one
thromboembolic event
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
May 01, 2022 - NSAID
Opioid increased risk of:
Any adverse event: RR
1.72 (95% CI 1.29 to 2.28)
Nausea: RR 2.72 … acetaminophen
Opioids increased risk of:
Any adverse event: RR
1.43 (95% CI 0.87 to 2.37)
Nausea … Opioids were associated with
increased likelihood of any adverse event (34% vs. 9%, RR 3.62, 95% CI … Topical ibuprofen was
associated with decreased likelihood of any adverse event, although the estimate … Opioids were
associated with increased likelihood of any adverse event (11 trials, pooled RR 1.72, 95%
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
January 01, 2007 - Layout 1
Background
Rheumatoid and psoriatic arthritis are
among the most disabling forms of
arthritis. Rheumatoid arthritis (RA), which
affects 1 percent of the U.S. adult
population (or upwards of 2 million
individuals), is an autoimmune disease that
involves inflammation of the synovium (a
thin layer of tissue lin…
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - We have added the following
sentence as a Key Point: “Adverse event
rates may be underestimated by … In adverse event
analysis, page 45, why weren't open label run-in phase data in the
withdrawal studies … In the adverse event analysis,
we only included data from the RCT phases
of multiphase studies in order … Some examples of
imbalances in adverse event rates that favor the safety of placebo
over adalimumab … We have added the following
sentence as a Key Point for KQ3: “Adverse
event rates may be underestimated
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - experiencing each of the
aforementioned outcomes was less than 1.5 percent; in 75
percent of studies the event … Selective outcome and analysis reporting likely
– Few studies reported bleeding requiring treatment; the event … Selective outcome and analysis reporting likely
– Few studies reported bleeding requiring treatment; the event … consistency
– Individual studies did not provide adequate information for precise
estimation of the event … Random effects meta-analysis
of event outcome in the framework of the generalized linear mixed
model
-
effectivehealthcare-admin.ahrq.gov/products/angina-heart-attack-treatments/research
December 01, 2019 - Skip to main content
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
September 01, 2009 - Layout 1
Background
Breast cancer is the most frequently
diagnosed noncutaneous cancer and the
second leading cause of cancer death after
lung cancer among women in the United
States. In 2008, an estimated 182,460 cases
of invasive breast cancer and 67,770 cases
of in situ breast cancer were diagnosed, and
40,480 wo…
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-asthma.pdf
April 01, 2019 - Standardized Library of Asthma Outcome Measures
Research White Paper
Standardized Library of Asthma Outcome Measures
Research White Paper
Standardized Library of Asthma Outcome Measures
Prepared for:
Agency for Healthcare Research and Quality
Center for Outcomes and Ev…
-
effectivehealthcare-admin.ahrq.gov/products/mhs4-patient-family-engagement/protocol
September 01, 2023 - Skip to main content
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0407_01-20-2011.pdf
January 01, 2011 - Effective Health Care
Topic Number: 0343
Document Completion Date: 3-23-11
1
Results of Topic Selection Process & Next Steps
Peripheral artery disease (PAD) will go forward for refinement as a systematic review. The scope of
this topic, including populations, interventions, comparators, and out…
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-cardiovascular-elderly_research.pdf
February 01, 2009 - myocardial infarction 60 (0.66) 96 (0.70) 99 (1.08) 151 (1.10) 164 (1.79) 249 (1.81)
Cerebrovascular event … Acute myocardial Infarction 0.93 (0.66, 1.32) 1.00 (0.76, 1.30) 1.03 (0.85, 1.27)
Cerebrovascular event … Acute myocardial infarction 0.89 (0.59, 1.33) 1.02 (0.75, 1.40) 1.16 (0.91, 1.48)
Cerebrovascular event
-
effectivehealthcare-admin.ahrq.gov/products/binge-eating/clinician
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effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rfviia.pptx
May 01, 2010 - pageaction=displayproduct&productID=450
Mean Differences in Mortality and Thromboembolic Event Rates … Mean Differences in Mortality and Thromboembolic Event Rates by Study and rFVIIa Indication
This figure … The mean differences in event rates for the direct (patient-centered) outcomes of total mortality and … The figures show mean differences in mortality and thromboembolic event rates, respectively, for each … harms of rFVIIa, our findings include:
There was no effect of rFVIIa on mortality or thromboembolic event
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/rfviia.pptx
May 01, 2010 - pageaction=displayproduct&productID=450
Mean Differences in Mortality and Thromboembolic Event Rates … Mean Differences in Mortality and Thromboembolic Event Rates by Study and rFVIIa Indication
This figure … The mean differences in event rates for the direct (patient-centered) outcomes of total mortality and … The figures show mean differences in mortality and thromboembolic event rates, respectively, for each … harms of rFVIIa, our findings include:
There was no effect of rFVIIa on mortality or thromboembolic event
-
effectivehealthcare-admin.ahrq.gov/products/ptsd-adult-treatment-update/research-2018
October 01, 2019 - Skip to main content
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effectivehealthcare-admin.ahrq.gov/products/asthma-nonpharmacologic-treatment/thermoplasty-systematic-review
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