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  1. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-update_executive.pdf
    March 01, 2011 - or thiazolidinediones. 7 Outcomes of Interest Overall, few studies contained sufficient data on event … We recommend improvements in adverse event and long-term outcome reporting, with predefined outcomes … (continued) Gastrointestinal Moderate Metformin was associated with twice as many GI adverse event rates
  2. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/type-2-diabetes-medications-2007_executive.pdf
    January 01, 2007 - Only one study reported an adverse event of thrombocytopenia and leucopenia, making comparisons between … cholecystitis compared with placebo in a pooled analysis. data NA FDA data were consistent with the adverse event
  3. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/sleep-apnea_executive.pdf
    July 01, 2011 - No adverse event with potentially long- term consequences was reported.
  4. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_executive.pdf
    May 01, 2010 - evaluate evidence of harm from rFVIIa in noncomparative studies, we described the unadjusted summary event … rates for mortality and thromboembolic events from the noncomparative studies, as well as event rates … Thromboembolic event risk differences (rFVIIa minus usual care) • There was no effect of rFVIIa on mortality … • rFVIIa use was associated with a higher thromboembolic event rate (risk difference 0.053; 95 percent … and thromboembolic events could not be evaluated due to limited reported events (one thromboembolic event
  5. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/main-apps-surv-rept-1-acute-pain.pdf
    May 01, 2022 - NSAID Opioid increased risk of: Any adverse event: RR 1.72 (95% CI 1.29 to 2.28) Nausea: RR 2.72 … acetaminophen Opioids increased risk of: Any adverse event: RR 1.43 (95% CI 0.87 to 2.37) Nausea … Opioids were associated with increased likelihood of any adverse event (34% vs. 9%, RR 3.62, 95% CI … Topical ibuprofen was associated with decreased likelihood of any adverse event, although the estimate … Opioids were associated with increased likelihood of any adverse event (11 trials, pooled RR 1.72, 95%
  6. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rheumatoid-arthritis-2007_executive.pdf
    January 01, 2007 - Layout 1 Background Rheumatoid and psoriatic arthritis are among the most disabling forms of arthritis. Rheumatoid arthritis (RA), which affects 1 percent of the U.S. adult population (or upwards of 2 million individuals), is an autoimmune disease that involves inflammation of the synovium (a thin layer of tissue lin…
  7. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
    September 01, 2011 - We have added the following sentence as a Key Point: “Adverse event rates may be underestimated by … In adverse event analysis, page 45, why weren't open label run-in phase data in the withdrawal studies … In the adverse event analysis, we only included data from the RCT phases of multiphase studies in order … Some examples of imbalances in adverse event rates that favor the safety of placebo over adalimumab … We have added the following sentence as a Key Point for KQ3: “Adverse event rates may be underestimated
  8. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
    September 01, 2014 - experiencing each of the aforementioned outcomes was less than 1.5 percent; in 75 percent of studies the event … Selective outcome and analysis reporting likely – Few studies reported bleeding requiring treatment; the event … Selective outcome and analysis reporting likely – Few studies reported bleeding requiring treatment; the event … consistency – Individual studies did not provide adequate information for precise estimation of the event … Random effects meta-analysis of event outcome in the framework of the generalized linear mixed model
  9. effectivehealthcare-admin.ahrq.gov/products/angina-heart-attack-treatments/research
    December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …
  10. Layout 1 (pdf file)

    effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_executive.pdf
    September 01, 2009 - Layout 1 Background Breast cancer is the most frequently diagnosed noncutaneous cancer and the second leading cause of cancer death after lung cancer among women in the United States. In 2008, an estimated 182,460 cases of invasive breast cancer and 67,770 cases of in situ breast cancer were diagnosed, and 40,480 wo…
  11. effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/white-paper-library-asthma.pdf
    April 01, 2019 - Standardized Library of Asthma Outcome Measures Research White Paper Standardized Library of Asthma Outcome Measures Research White Paper Standardized Library of Asthma Outcome Measures Prepared for: Agency for Healthcare Research and Quality Center for Outcomes and Ev…
  12. effectivehealthcare-admin.ahrq.gov/products/mhs4-patient-family-engagement/protocol
    September 01, 2023 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …
  13. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/TND_0407_01-20-2011.pdf
    January 01, 2011 - Effective Health Care Topic Number: 0343 Document Completion Date: 3-23-11 1 Results of Topic Selection Process & Next Steps  Peripheral artery disease (PAD) will go forward for refinement as a systematic review. The scope of this topic, including populations, interventions, comparators, and out…
  14. effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotic-medicine-cardiovascular-elderly_research.pdf
    February 01, 2009 - myocardial infarction 60 (0.66) 96 (0.70) 99 (1.08) 151 (1.10) 164 (1.79) 249 (1.81) Cerebrovascular event … Acute myocardial Infarction 0.93 (0.66, 1.32) 1.00 (0.76, 1.30) 1.03 (0.85, 1.27) Cerebrovascular event … Acute myocardial infarction 0.89 (0.59, 1.33) 1.02 (0.75, 1.40) 1.16 (0.91, 1.48) Cerebrovascular event
  15. effectivehealthcare-admin.ahrq.gov/products/binge-eating/clinician
    December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …
  16. effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research
    December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …
  17. effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/rfviia.pptx
    May 01, 2010 - pageaction=displayproduct&productID=450 Mean Differences in Mortality and Thromboembolic Event Rates … Mean Differences in Mortality and Thromboembolic Event Rates by Study and rFVIIa Indication This figure … The mean differences in event rates for the direct (patient-centered) outcomes of total mortality and … The figures show mean differences in mortality and thromboembolic event rates, respectively, for each … harms of rFVIIa, our findings include: There was no effect of rFVIIa on mortality or thromboembolic event
  18. effectivehealthcare-admin.ahrq.gov/sites/default/files/rfviia.pptx
    May 01, 2010 - pageaction=displayproduct&productID=450 Mean Differences in Mortality and Thromboembolic Event Rates … Mean Differences in Mortality and Thromboembolic Event Rates by Study and rFVIIa Indication This figure … The mean differences in event rates for the direct (patient-centered) outcomes of total mortality and … The figures show mean differences in mortality and thromboembolic event rates, respectively, for each … harms of rFVIIa, our findings include: There was no effect of rFVIIa on mortality or thromboembolic event
  19. effectivehealthcare-admin.ahrq.gov/products/ptsd-adult-treatment-update/research-2018
    October 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …
  20. effectivehealthcare-admin.ahrq.gov/products/asthma-nonpharmacologic-treatment/thermoplasty-systematic-review
    October 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

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