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effectivehealthcare-admin.ahrq.gov/products/safety-vaccines/research
January 01, 2022 - Skip to main content
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effectivehealthcare-admin.ahrq.gov/products/high-risk-drugs/protocol
September 01, 2023 - to serious adverse effects (e.g., bleeding). 7 , 8 The 2019 National Action Plan for Adverse Drug Event … Advancing Medication Safety: Establishing a National Action Plan for Adverse Drug Event Prevention.
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effectivehealthcare-admin.ahrq.gov/products/renal-disease-therapies/abstract
December 01, 2019 - primarily mediated by changes in blood pressure, but differs by underlying comorbidity and type of CVD event
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effectivehealthcare-admin.ahrq.gov/products/mhs4-computerized-cds/rapid-research
February 01, 2024 - Skip to main content
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effectivehealthcare-admin.ahrq.gov/products/urinary-incontinence-treatment/research-protocol
December 01, 2020 - exposed to different clinical interventions. 92 , 97 , 98
The number needed to treat to prevent one event … rate - treatment group event rate). … number of avoided or excess events (respectively) per 1000 population is the difference between the two event … rates multiplied by 1000:
(control group event rate - treatment group event rate)*1000
We will … a week (~56 g/24 hours, 95% confidence interval 44-67)
Summary of Protocol Amendments
In the event
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cer-214-afib-disposition-comments.pdf
October 30, 2019 - emphasis on c-
statistics and the corresponding lack of focus on
synthesizing evidence about actual event … I would like to see this report more clearly
show and synthesize the evidence about event
rates, because … We have modified the tables in
KQ1 and KQ2 to better
highlight the event rates for the
various outcomes … Peer Reviewer #2 Results Many results on event rates, notably in Tables 6-8,
could be converted to a … The plots could also use different
colors or symbols for different event definitions.
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effectivehealthcare-admin.ahrq.gov/products/incident-user-design/research
August 01, 2019 - effectiveness evidence for another reason: accurate reflections of the induction period or time-to-event … incident use of an intervention and its alternative, investigators can compare cohorts’ times until event … safer than older drugs because their apparent rate would be lower; investigators would observe a higher event … months of therapy and persist with therapy to be eligible for the study, which can distort the absolute event … Studies that opt for (event) risk scores instead of propensity scores to control confounding would also
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effectivehealthcare-admin.ahrq.gov/products/renal-function/research-protocol
December 01, 2019 - as independent risk predictors of morbidity and mortality in populations following an acute ischemic event … chronic kidney disease; hs = high sensitivity; KQ = key question; MACE = major adverse cardiovascular event … kidney disease; ESRD = end-stage renal disease; KQ = key question; MACE = major adverse cardiovascular event … disease; ECG = electrocardiogram; ESRD = end-stage renal disease; MACE = major adverse cardiovascular event … myocardial infarction
Tn = troponin
UA = unstable angina
Summary of Protocol Amendments
In the event
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-applicability_methods.pdf
January 01, 2011 - Many of these elements are routinely captured in
most systematic reviews (for example, demographics, event … patients
had less severe CHF, more comorbidities and were more likely
to have had a recent cardiac event … include attrition before
randomization and reasons
(nonadherence, side-effects,
nonresponse)14,15
Event … rate of heart disease (by up to 50%) than expected
for a similar population in the community.16
Event … the participating centers and
surgeons may influence both the effectiveness of treatment and adverse event
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effectivehealthcare-admin.ahrq.gov/sites/default/files/methods_guide_atkins.pdf
January 01, 2011 - Many of these elements are routinely captured in
most systematic reviews (for example, demographics, event … patients
had less severe CHF, more comorbidities and were more likely
to have had a recent cardiac event … include attrition before
randomization and reasons
(nonadherence, side-effects,
nonresponse)14,15
Event … rate of heart disease (by up to 50%) than expected
for a similar population in the community.16
Event … the participating centers and
surgeons may influence both the effectiveness of treatment and adverse event
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effectivehealthcare-admin.ahrq.gov/products/blood-clots-hip-knee-surgery/research-protocol
December 01, 2019 - observational studies which compare pharmacologic VTE prophylaxis methods will be used to report VTE event … Baseline risk of bleeding will be summarized using event rates from trials or large observational studies … KQ 3 will be addressed by qualitatively reporting event rates of both asymptomatic and symptomatic pulmonary … the change scores will be calculated using the method proposed by Follman and colleagues. 10 In the event … thromboembolism
WMD
Weighted mean difference
Summary of Protocol Amendments
In the event
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effectivehealthcare-admin.ahrq.gov/products/acs-pci-adjunctive-devices/research-protocol
December 01, 2019 - Eligibility criteria, demographics
Population
Events rates markedly different than in the community
Event … syndrome
EPC
Evidence-based Practice Center
MACE
major adverse cardiac event … TIMI
thrombolysis in myocardial infarction
Summary of Protocol Amendments
In the event
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effectivehealthcare-admin.ahrq.gov/products/transparency-neuropathy/research
December 01, 2019 - differed in the number enrolled (8 studies, 32%), the primary outcome (14 studies, 56%), and adverse event
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effectivehealthcare-admin.ahrq.gov/products/peripheral-artery-disease-effectiveness/abstract
December 01, 2019 - procedure indication) as well as propensity scores used as inverse probability weights in the time to event
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diverticulitis-research-protocol.pdf
January 01, 2019 - at least 100 participants (who all receive the same
intervention) will allow estimates of adverse event … † Restricting to larger studies will allow estimates of adverse event rates to be
increasingly precise … report results as per the
existing systematic review
For Key Questions 1b and 1c, we will focus on event … For Key Question 3, we will focus on event rates of the clinical outcomes and harms. … nonpharmacologic, elective
surgical) to their comparators, for their effects, primarily with ORs of event
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effectivehealthcare-admin.ahrq.gov/products/diverticulitis/protocol
October 01, 2019 - report results as per the existing systematic review
For Key Questions 1b and 1c, we will focus on event … interventional radiology) to their comparators, for their effects, primarily with odds ratios (ORs) of event … For Key Question 3, we will focus on event rates of the clinical outcomes and harms. … nonpharmacologic, elective surgical) to their comparators, for their effects, primarily with ORs of event … ***Restricting to larger studies will allow estimates of adverse event rates to be increasingly precise
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - For dichotomous data, each event will be counted as if it represents a
unique individual; because a … The dose of each medication that is
associated with an adverse event will be recorded to facilitate … event!outcome!data!for!extraction!in!the!comparative!effectiveness!review!
Adverse!event! … In the event that
studies cannot be pooled, evidence tables will be produced and a narrative summary … In the event of protocol amendments, the date of each amendment will be accompanied by
a description
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effectivehealthcare-admin.ahrq.gov/products/cardio-dental/research
July 01, 2023 - Skip to main content
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/multiple-sclerosis_executive.pdf
April 01, 2015 - At Least
1 Serious
Adverse
Event
Treatment
Discontinuation
for Adverse
Event
Comparator … The included studies used a wide range of reporting
methods and adverse event categories that precluded … Studies reporting reasons for discontinuing medication
DMT
Total
Number
of Studies
Adverse
Event … Long-term effect of
early treatment with interferon beta-1b after a first clinical event
suggestive … Multiple sclerosis
patients’ benefit-risk preferences: serious adverse event risks versus
treatment
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effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-year-in-review-2020.pdf
January 01, 2020 - default/files/2020-08/PreventiveServices-P2P-FPM-Report_FINAL_508.pdf
https://www.nationalacademies.org/event … care-interventions-for-individuals-with-dementia-and-their-caregivers-phase-two-meeting-1-and-public-workshop
https://www.nationalacademies.org/event … MEDCACId=77&bc=AAACAAAAAAAA
https://www.nationalacademies.org/event/04-15-2020/care-interventions-for-individuals-with-dementia-and-their-caregivers-phase-two-meeting … -1-and-public-workshop
https://www.nationalacademies.org/event/04-15-2020/care-interventions-for-individuals-with-dementia-and-their-caregivers-phase-two-meeting