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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-introduction_methods.pdf
July 01, 2012 - Rarely are medical tests evaluated in randomized controlled trials with
representative patient populations … Causal chain diagram
In rare but ideal cases, a test is evaluated in a comprehensive clinical … Ideally,
the entire chain should be considered and evidence regarding each link assembled, evaluated … clinical importance.2 One consequence of this indirect
relationship is that medical tests tend to be evaluated
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effectivehealthcare.ahrq.gov/sites/default/files/cer-226-labor-dystocia-comments.pdf
May 14, 2020 - The
majority of interventions evaluated in this review are used to promote
physiologic labor (or to … The diagnosis of prolonged labor was not the outcome
evaluated as specified in the KQ; rather it was … restrict this to labor dystocia, I think this section needs to be
limited to the articles that truly evaluated … We now clarify that many
studies evaluated
interventions in nulliparous
(women who have not
previously … Discussion/
Conclusion
Peer Reviewer #1 The interventions evaluated also were NOT to treat dystocia
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/field-triage-glascow-disposition-170415.pdf
January 12, 2017 - As noted in the “Assessing Research
Applicability” section, we evaluated factors
important for understanding … As noted in the
Applicability section, no study evaluated how
predictive utility varied according to … As described in
the Results, no study evaluated effects of the
tGCS vs. mGCS or SMS on clinical outcomes … TEP Reviewer #4 Methods There is no mention of how key question 4 is
evaluated. … These
differences were statistically significant, in part
due to the large sample sizes evaluated in
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - Indicating the study
assessed change means it evaluated the characteristic or
symptom at baseline and … Four studies evaluated therapies in
postmenopausal women. … A single poor quality study evaluated tamoxifen, which
acts as an anti-estrogen within breast tissue … Fertility
outcomes were not evaluated in the UAE-only trials. … One
compared myomectomy to hysterectomy, the remainder
evaluated outcomes in women treated by UAE,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/episodic-migraine-surveillance-report-2.pdf
June 01, 2022 - Briefly, the report evaluated acute treatments in
adult patients with episodic migraine and addressed … Paracetamol
(acetaminophen)
No study in the original report
evaluated this comparison
One RCT4 … NSAIDS
Since the previous literature update (Surveillance Report 1), two RCTs5, 6 evaluated NSAIDs. … One RCT (n=100)5 evaluated lidocaine versus dexketoprofen trometamol. … The other RCT (n=44),6 which was
underpowered, evaluated intravenous ibuprofen versus placebo and found
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-risk-bias.ppt
June 01, 2012 - This range of study limitations was evaluated in a series of studies by Whiting et al., which indicated … The first systematic review, conducted by West et al. (2002), evaluated 18 tools. … In one such review, West et al. (2002) evaluated 18 bias-assessment tools, all of which were intended … The second systematic review, conducted by Whiting et al. (2005), evaluated 91 tools. … In another such systematic review, Whiting et al. (2005) evaluated 91 bias-assessment tools.
-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-risk-bias.ppt
June 01, 2012 - This range of study limitations was evaluated in a series of studies by Whiting et al., which indicated … The first systematic review, conducted by West et al. (2002), evaluated 18 tools. … In one such review, West et al. (2002) evaluated 18 bias-assessment tools, all of which were intended … The second systematic review, conducted by Whiting et al. (2005), evaluated 91 tools. … In another such systematic review, Whiting et al. (2005) evaluated 91 bias-assessment tools.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
January 01, 2016 - • Studies evaluated IH in multiple locations (vs. specific
anatomic areas) as most studies included … Beta-Blockers
Eighty-one studies (25 comparative studies and 56 case
series) evaluated propranolol … Few studies addressed imaging modalities, and those that
did evaluated modalities to assess hepatic … Most comparative studies evaluated laser
treatments including short-pulse and longer pulse PDL,
Nd: … Two studies evaluated cryotherapy,
one of which compared it to photothermolysis with
intense pulsed
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/crohns-disease_disposition-comments.pdf
February 25, 2014 - We re-evaluated the strength of
evidence for budesonide vs.
placebo to maintain remission. … This dose was evaluated in the phase III efficacy trial for Crohn’s
disease. … For those
treatments that are not indicated for Crohn’s disease, the recommended doses evaluated in … Also evaluated
were the rate of clinical remission, response-70, response-100, and the Inflammatory … This statement is contradictory
to the data being evaluated and is confusing.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
April 23, 2019 - listed harms were associated with these
osteoporosis drug classes, we changed them as
follows: ‘Harms evaluated … for possible association with
long-term osteoporosis drug therapy’ and ‘Harms
outcomes evaluated.’ … listed harms were
associated with these osteoporosis drug classes, we
changed them as follows: ‘Harms evaluated … for
possible association with long-term osteoporosis drug
therapy’ and ‘Harms outcomes evaluated.’ … Per the
protocol, we evaluated BMD change as an outcome
only in long-term or drug holiday trials that
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/antiplatelet-treatment_disposition-comments.pdf
September 25, 2013 - In
addition, the generic clopidogrel available in the United States
has been evaluated only through … Rather, it is very consistent with how antiplatelet
therapies are evaluated for efficacy. … For example, clopidogrel
was evaluated in the CURE trial and prasugrel was evaluated
in the TRITON‐TIMI … We agree that MACE represents an outcome of interest
for the tests evaluated in the report. … Consistency, directness and precision are generally
evaluated across studies.
-
effectivehealthcare.ahrq.gov/sites/default/files/coronary-artery-disease-testing_executive.pdf
March 01, 2011 - Harms related to both the initial test and subsequent testing
are evaluated. … Two investigators
independently evaluated each full-text article for final
inclusion. … Each study evaluated was independently reviewed for
quality by two team members. … In light of this, test comparisons were
evaluated according to pretest risk as specified by authors … None of the included studies evaluated issues
of unnecessary testing or treatment in patients
without
-
effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/epc-march-2023-grand-rounds-slides.pdf
January 01, 2023 - • We identified no studies that directly evaluated or compared implementation strategies, which was … more than doubled the number of studies that
addressed implementation, we found none that directly evaluated … outcomes reported were often short-term; long-term sustainability and implementation
issues were not evaluated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_disposition-comments.pdf
January 27, 2014 - Our evidence grading evaluated risk of bias, consistency,
directness, and precision of the body of evidence … An explanation of how pain was evaluated is
included in each study description. … Several studies evaluated antimicrobial dressings. … wound dressings and antibiotics and
noncomparative studies that evaluated surgical dressings. … (ES-18) Our review
evaluated the effect of advanced wound dressings on
healing, pain, and infection
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_disposition-comments.pdf
September 01, 2011 - Source: www.effectivehealthcare.ahrq.gov
6
Peer Reviewer #7 Introduction Table 1 (DMARDs evaluated … Peer Reviewer #7 Results (Pg 39,
line 57)
Says evaluated only children with polyarticular JRA, but … is not
a relative measure like the Pediatric ACR score (JRA core set), so I
believe it should be evaluated … Pg 39) Reviewer requests the text be changed to: One good-quality
randomized discontinuation study evaluated … added: “This trial
included an 8-year extension, during which efficacy and safety
continued to be evaluated
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - • Emerging technologies have not been evaluated in
randomized trials. … No randomized trials evaluated
cryosurgery, and the majority of reports included
patients with T3-T4 … Cryosurgery Low • No randomized trials evaluated cryosurgery. … Primary androgen Low • No randomized trials evaluated primary ADT. … Age Low • 1 randomized trial evaluated survival with RP vs. WW
according to age in men.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cystic-fibrosis-hgh_appendixes.pdf
January 01, 2009 - Used as a lab marker
to evaluated cancer risk in patients receiving recombinant human growth hormone … Strength of evidence for outcomes evaluated in Key Question 1 (continued)
Quality assessment
Summary … Strength of evidence for outcomes evaluated in Key Question 1 (continued)
Quality assessment
Summary … Strength of evidence for outcomes evaluated in Key Question 1 (continued)
Quality assessment
Summary … Strength of evidence for outcomes evaluated in Key Question 1 (continued)
Quality assessment
Summary
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-health-app-protocol-updated.pdf
January 01, 2018 - funding sources and future plans for growth and partnership
with health delivery providers will be evaluated … An
additional 18 apps will
be evaluated by two
team members during
public review.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/catd-protocol-draft_0.pdf
November 02, 2018 - The efficacy of some older nonprescription agents has been evaluated in RCTs and
systematic reviews, … To clarify which comparisons were being evaluated for which
treatments. … Table 1 Details not
provided for which
cognitive domains
will be evaluated
as treatment
outcomes … Some imputation methods might be appropriate (to be
evaluated on a case-by-case basis). … Some imputation methods might be
appropriate (to be evaluated on a case-by-case basis).
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pediatric-ehr_research-protocol.pdf
January 01, 2014 - literature as more important than others, and the degree to which these
functionalities have been evaluated … Questions of applicability will therefore be important to address if EHRs are evaluated in very
specific … functionality is well accepted;
therefore, the GQs will examine functionalities that have been or are being evaluated … published and grey literature, with the ultimate goal
of identifying functionalities that have been evaluated