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  1. effectivehealthcare.ahrq.gov/sites/default/files/hip-fracture-pain_surveillance.pdf
    July 08, 2015 - Systemic Analgesia 3 RCTs (n=214) evaluated different types of systematic analgesia. … Additionally, three cohort studies (n = 696) evaluated 3-in-1, femoral, and lumbar plexus plus sciatic … Up-to-date No new research was found Rehabilitation: One RCT (n = 37) evaluated physical therapy … Systemic Analgesia: 3 RCTs (n=214) evaluated different types of systematic analgesia. … Multimodal Pain Management: Two cohort studies (n = 226) evaluated multimodal pain management versus
  2. effectivehealthcare.ahrq.gov/sites/default/files/back-pain-treatment_research_executive.pdf
    February 01, 2016 - We also evaluated comparisons of the combination of one included therapy plus another included therapy … We evaluated effects of interventions on reduction or elimination of low back pain, including related … ,24 and cohort studies were evaluated using criteria developed by the U.S. … Acetaminophen vs. placebo, chronic LBP Insufficient No study evaluated acetaminophen vs. placebo. … IFT: Adverse events Insufficient No study evaluated harms of IFT.
  3. effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
    October 01, 2015 - We also evaluated adverse effects of diagnostic testing (e.g., false- positives, labeling, anxiety, … No trial evaluated effects of BCG versus no intravesical therapy on risk of all-cause mortality. … • Five trials that evaluated different epirubicin regimens that included maintenance therapy found … We included 14 trials (in 19 publications) that evaluated clinical outcomes of augmented (fluorescent … Adverse Effects of Treatments: Patient Characteristics • No study evaluated how harms of treatment
  4. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cannabis-2023-surv-rep-4.pdf
    January 01, 2023 - In addition, it evaluated a topical (oromucosal) low- tetrahydrocannabinol (THC) to CBD product, and
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/predictors-trauma-care_research-protocol.pdf
    May 31, 2017 - Measures) The intervention is usually the treatment or health service of interest that is being evaluated … In this review the physiologic measures are what are evaluated. … Studies will be evaluated using appropriate study-design specific criteria24 or an appropriate tool … Each study evaluated will be independently reviewed for risk of bias by two team members. … For each measure identified in the review we will consider predictive utility evaluated in terms of
  6. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
    October 01, 2011 - Adverse events were evaluated from studies of the drugs used for osteoarthritis, rheumatoid arthritis … Specific adverse events evaluated include CV [stroke, myocardial infarction, congestive heart failure … One observational study evaluated etodolac and nabumetone, but estimates were imprecise. … GI and CV safety: Salsalate Insufficient No randomized trial or observational study evaluated risk of … Other topical NSAIDs evaluated in head-to-head trials have not been FDA approved.
  7. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-194-disposition-comments-inhaled-corticosteroids.pdf
    March 19, 2018 - Seasonality was not a prespecified subgroup of interest and thus was not further evaluated in this … Each study included in this review was evaluated for risk of bias (ROB) using tools approved in the … Each study included in this review was evaluated for ROB using tools approved in the protocol and … The literature has been exhaustively and objectively evaluated. … In particular, varying duration of the evaluated interventions could have a large impact on how the
  8. effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-treatment-adherence_executive.pdf
    September 22, 2011 - We developed this classification system based on two previous systematic reviews that evaluated the … (Strength of evidence = insufficient) Three studies evaluated a system-level intervention’s effect … The study evaluated the treatment adherence of patients who were prescribed RibaPak, available in 400 … The intervention included regular consultation with a nurse, who evaluated the patients’ understanding … Finally, one poor-quality prospective cohort study,31 conducted in Italy, evaluated the Together To
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-cough_disposition-comments.pdf
    January 07, 2013 - For cough frequency, we evaluated validity by concurrence with measures of other constructs (e.g., … For severity/QOL instruments, we evaluated validity by looking at concurrence with Source: http … We evaluated responsiveness of both frequency and severity/QOL measures by reporting data on changes … For cough severity/impact instruments, we evaluated validity by looking at concurrence with measures … Unfortunately, no studies evaluated its measurement accuracy in the pediatric population.
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-antigen-3-gene_research.pdf
    April 01, 2013 - Key Question 3: In patients with a positive biopsy for prostate cancer who are being evaluated to distinguish … The EPC, with input from the Stakeholder Panel, evaluated a variety of study designs for their potential … EPC staff evaluated the appropriateness of various study designs to address the research needs and further … Hypothetical scenarios for test use can be developed and evaluated in physicians or patients to determine … A better understanding of this issue is needed if PCA3 is to be properly evaluated in the context of
  11. Layout 1 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-anemia_executive.pdf
    May 01, 2006 - undergoing cancer treatment, the comparative effectiveness of epoetin and darbepoetin has not been evaluated … Numeric changes on QoL instrument scales must be empirically evaluated to determine whether the degree … or early after starting treatment (e.g., Hb increase, serum ferritin, reticulocyte increase), were evaluated
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
    September 01, 2012 - Two reviewers separately evaluated the abstracts for inclusion or exclusion. … Modifiers of Outcomes by Type of Progestogen Twenty-seven studies with distinct populations evaluated … Seven studies with four dose/interval combinations evaluated progesterone vaginal gel or suppository … Five studies with five dose/interval combinations and varied timing of initiation evaluated oral micronized … No studies directly assessed adherence to treatment or evaluated whether varying frequency or dose influenced
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-artery-stenting_research-protocol.pdf
    August 19, 2011 - ≥18 years) • For KQs 1, 4a, and 5a: Patients who undergo diagnostic coronary angiography and are evaluated … All patients considered to be candidates for coronary interventions can be evaluated on the basis of … coronary lesions (e.g., vulnerable plaques) • For KQs 2, 4b, and 5b: Patients who need PCI and are evaluated … procedure (either immediately before or during the procedure) • For KQs 3, 4c, and 5c: Patients evaluated … Assessing Applicability The following factors will be evaluated to assess applicability of study
  14. effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
    January 01, 2009 - Study Selection and Data Extraction—Two authors separately evaluated potentially eligible papers and … These are ample reasons why new medical tests should be thoroughly evaluated before they are introduced … Finally, diagnostic accuracy is evaluated in a clinical study group that closely resembles the population
  15. effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
    January 01, 2009 - Study Selection and Data Extraction—Two authors separately evaluated potentially eligible papers and … These are ample reasons why new medical tests should be thoroughly evaluated before they are introduced … Finally, diagnostic accuracy is evaluated in a clinical study group that closely resembles the population
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-257-antenatal-care-disposition-comments.pdf
    June 28, 2022 - For example, only 2 RCTs were evaluated with regards to replacing some routine antenatal visits with … Where outcomes differed across studies, we evaluated and reported on these separately and took
  17. effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-201-indoor-allergen-reduction-asthma-evidence-summary.pdf
    February 01, 2018 - evidence base lacks sufficient high-quality studies to inform useful conclusions for the interventions evaluated … The evidence base could also be evaluated with greater precision if outcome reporting were improved
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
    January 01, 2014 - We evaluated the literature for data on wound healing, recurrence rates, and intermediate outcomes, … Study Selection Two independent reviewers evaluated each title, abstract, and full article. … advanced wound dressings • 1 evaluated antibiotics • 8 (9) compared surgery with compression … • 14 evaluated surgical procedures Excluded 541 Reasons for Exclusion at the Abstract Review … acellular human skin equivalents.17, 19, 32 These studies had a high risk of bias, evaluated a variety
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/restless-legs_executive.pdf
    November 01, 2012 - We evaluated RLS symptom severity and outcome, patient-reported sleep quality, and disease-specific … Studies deemed potentially eligible for inclusion by either investigator were further evaluated. … We evaluated individual domains qualitatively and assigned a summary rating of high-, moderate-, or … One low-quality RCT evaluated near-infrared light therapy compared with sham treatment. … Two small, good quality RCTs evaluated iron therapy (one intravenous and one oral) in patients with
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/gerd-disposition-120104.pdf
    April 01, 2011 - Domperidone is not being evaluated; it is listed as a co-intervention. … The entire dataset was evaluated; however, in this subcategory (which is a very difficult category to … Healing of EE - Two multicenter, double-blind, randomized, active- controlled, 8-week trials evaluated … EE maintenance - A 6-month, multicenter, double-blind, randomized, placebo-controlled trial evaluated … with prescription and over-the- counter (OTC) PPIs.15 According to the consumer update; the FDA has evaluated

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