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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-imaging_disposition-comments.pdf
October 01, 2014 - In the
studies that examined imaging to evaluate treatment, we
abstracted data on whether the studies … both for lay and professional readers, is that very few
research studies on the use of imaging to evaluate … For example, in the first paragraph,
we now describe the ideal tool that could be used to
evaluate … However, to evaluate
residual disease in patients with positive margins at lumpectomy
prior to re-excision … In addition, some diagnostics tests are
synergistic and are ordered to better evaluate findings from
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-215-depression-older-adults-executive-summary.pdf
March 01, 2019 - : summary
statements based on findings and statistical significancea
Key Question (KQ) 1 aimed to evaluate … Although we aimed to evaluate
SSRIs and SNRIs on a class basis, data for few
individual drugs within … Although we aimed to evaluate some therapies
on a class basis (SSRI and SNRI), we did not find
evidence … None of the trials were powered to evaluate harms
as they were all designed to assess efficacy. … Furthermore, when
studies did evaluate continuation or maintenance,
they were considered to have higher
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-0520-131115.pdf
May 29, 2025 - Reviews did not evaluate asymptomatic
patients with suspected or known CAD.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/tympanostomy-tubes_research-protocol.pdf
November 16, 2015 - The objectives for the systematic review are: 1) to evaluate the effectiveness of
tympanostomy tubes … in children with chronic otitis media with effusion and recurrent
acute otitis media, 2) to evaluate … the necessity for water
precautions in children with tympanostomy tubes, and 4) to evaluate the comparative … We will evaluate the risk of bias factors as possible explanations for any
heterogeneity. … study, patient,
and intervention features, (as listed in the KQs) to evaluate dose-response.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/abnormal-uterine-bleeding_research-protocol.pdf
November 21, 2011 - pediatricians, family physicians, advanced
practice nurses, and internists, will encounter the need to evaluate … The proposed report will not evaluate evidence for older compounds that
are no longer commonly prescribed … To be considered for
inclusion, clinical research studies must evaluate a nonsurgical intervention, … will include data from controlled
clinical trials (e.g., randomized controlled trials) designed to evaluate … intervention (i.e.,
studies on prevalence, etiology, diagnosis will be excluded)
Studies that evaluate
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
April 01, 2010 - Most studies evaluate some form of exercise therapy; however, a variety of physical
therapy interventions … Assessment of Methodological Quality of Individual Studies
We will evaluate the quality of studies … Abstract Predefined Criteria for Quality for Critical Appraisal
We will evaluate risk of bias in … We will
evaluate applicability of the studies by using criteria of external validity. … For observational studies, we will evaluate strategies to reduce bias in study design and
analysis,
-
effectivehealthcare.ahrq.gov/sites/default/files/vte-protocol-8-4-10.pdf
February 01, 2008 - The
second search will be used to identify studies which evaluate pharmacologic or
mechanical methods … KQs 1-9 evaluate patient’s undergoing major orthopedic surgery; we will evaluate the
results separately … KQs 10 and 11 evaluate patients undergoing
other orthopedic surgeries; we will evaluate the results … For each KQ, we will also evaluate the results based on the year of publication
(earlier than 2001 vs … For example, when a meta-analysis is performed, we will
evaluate the confidence interval around the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/blood-clots-hip-knee-surgery_research-protocol.pdf
February 01, 2008 - The
second search will be used to identify studies which evaluate pharmacologic or
mechanical methods … KQs 1-9 evaluate patient’s undergoing major orthopedic surgery; we will evaluate the
results separately … KQs 10 and 11 evaluate patients undergoing
other orthopedic surgeries; we will evaluate the results … For each KQ, we will also evaluate the results based on the year of publication
(earlier than 2001 vs … For example, when a meta-analysis is performed, we will
evaluate the confidence interval around the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
September 20, 2013 - excluded.a
● Interventions
For all KQs, the intervention is a core-needle biopsy done to evaluate … □ Physician experience
□ Availability of equipment
□ Availability of (qualified) pathologists to evaluate … We will
evaluate the robustness of our findings in sensitivity analyses that exclude studies at high … Assessing Applicability
We will follow the Methods Guide19 to evaluate the applicability of included … We will evaluate studies (or subgroups of studies) of elderly women
(operationally defined as patients
-
effectivehealthcare.ahrq.gov/sites/default/files/estimation-and-reporting_chapter-3.pptx
January 01, 2013 - A test is conducted to evaluate if a subgroup variable has a statistically significant interaction with … A test for interaction is conducted to evaluate if a subgroup variable has a statistically significant … Evaluate chance findings by testing for interaction.
Avoid bias by adhering to sound study design. … Investigators must evaluate the observed HTE to determine whether a finding is indicative of true heterogeneity
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/kidney-disease-medicine_executive.pdf
January 01, 2012 - • Limits: Only one trial was designed to evaluate clinical vascular outcomes. … Accurate
information on screening and monitoring harms is needed
to evaluate their overall impact in … - Evaluate the impact of patient factors (e.g., eGFR
severity, albuminuria, age) on persistence. … • Long-term RCTs of CKD treatment adequately
powered to evaluate impact on clinical outcomes. … • Patient-level meta-analyses of treatment RCTs to
evaluate the effect of treatments relative to
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced-appendix-3.xlsx
June 24, 2022 - external control groups derived from RWD for single-arm trials and other studies
ISPE_2020 Design Evaluate … FDA Data There are validation protocols that evaluate how well the data reflects the patient population … captures patient medical history and preexisting conditions, as well as followup information needed evaluate … NAM2019 Could real-world providers in these settings accurately recognize or evaluate this event or … ISPE_2020 Generalizability Evaluate representativeness and/or generalizability of the RWE or describe
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
January 01, 2025 - lack of access to care.26, 27 Given the challenges
mentioned, we will conduct a systematic review to evaluate … Assessment of the Risk of Bias of Individual Studies
We will evaluate the risk of bias of the included … We will evaluate heterogeneity between studies using I2 indicator. … patients and caregivers), consistency
of results (based on qualitative and statistical approaches to evaluate … We will use this information to evaluate applicability of the evidence to
real-world clinical practice
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-270-bimp-executive-summary.pdf
May 01, 2024 - populations.3-6 Existing systematic reviews on behavioral
therapies are notably outdated and do not evaluate … comprehensive systematic review and the
accumulation of new evidence, we conducted a systematic review to evaluate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ocd-protocol.pdf
August 15, 2023 - “If screening suggests [obsessive compulsive] symptoms may be present,
clinicians should fully evaluate … We will evaluate outcomes as listed in the Study Eligibility Criteria section,
focusing on sensitivity … As described
below, we will evaluate the strength of evidence (SoE) for these outcomes. … We may also
evaluate SoE for other included outcomes. … Assessment of Quality and/or Methodological Risk of Bias of Individual Studies
We will evaluate each
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatitis-c-treatment-future_research.pdf
April 01, 2013 - In fact, a number of the research gaps
(such as the need for studies that evaluate an effectiveness … paradigm, studies that evaluate
patients with important comorbidities, and studies that are not funded … For example, the CER did
not evaluate patients with HIV or hepatitis B virus coinfection, or patients … It is not possible to evaluate the
association between achieving and not achieving an SVR following … Long-term
followup to
adequately
evaluate
clinical
outcomes.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
March 14, 2024 - lack of access to
care.26, 27 Given the challenges mentioned, we will conduct a systematic review to evaluate … Assessment of the Risk of Bias of Individual Studies
We will evaluate the risk of bias of the included … We will evaluate heterogeneity between studies using I2 indicator. … patients and caregivers), consistency
of results (based on qualitative and statistical approaches to evaluate … We will use this information to evaluate applicability of the evidence to
real-world clinical practice
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/plant-based-treatments-revised-protocol.pdf
March 29, 2023 - We will evaluate the persistence of
benefits or harms by evaluating the three periods identified in … To evaluate
subgroup effects, we will summarize within-study analyses of subgroup differences and perform … When data are available we will also evaluate the proportion of
patients meeting thresholds for clinically … We will evaluate how the new evidence may alter the
findings of the systematic review and will make … Similarly, trials that use active run-in periods
evaluate highly selected populations who tolerated
-
effectivehealthcare.ahrq.gov/sites/default/files/web-based_osheroff_respondent.pdf
January 01, 2009 - (Process/Thought)-‐Flow
Opportunities
Inform,
Deliberate,
Decide,
Implement,
Evaluate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/copd-anticholinergic-medicines_research.pdf
December 01, 2009 - Our objective was to evaluate the comparative effectiveness of regimens
containing tiotropium versus … The objective of this study was to evaluate the comparative effectiveness of
regimens containing tiotropium … We conducted several sensitivity analyses to
evaluate the impact on study results. … Fourth, follow-up was
stopped after 365 days to evaluate results over a one-year period. … Thus, there is still
need to evaluate tiotropium safety in patient populations who are treatment naïve