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Showing results for "evaluate".

41. Research Protocol: Diabetes Medications for Adults With Type 2 Diabetes: An Update Focused on Monotherapy and Add-On Therapy to Metformin (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-update-2015_research-protocol.pdf
    January 01, 2015 - for included studies of SGLT-2 inhibitors and GLP-1 agonists only) § Heart rate (will evaluate for … Comparisons • We will include studies that evaluate a comparison of interest (see Table 1). … ^ We will not evaluate this outcome for metformin vs. sulfonylurea comparisons as the evidence was … † We will not evaluate this outcome for metformin vs. thiazolidinedione or metformin vs. sulfonylurea … § We will evaluate this outcome only for comparisons that include a SGLT-2 inhibitor.

42. Breast-Cancer-Imaging Technical-Brief (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-cancer-imaging_technical-brief.pdf
    October 01, 2014 - Although multiple imaging modalities to evaluate treatment response in patients with metastatic breast … From the published literature, we abstracted data on the types of imaging used to evaluate treatment … Overview of Imaging Modalities Currently Used To Evaluate Treatment of Metastatic Breast Cancer • … We limited our data abstraction to studies dealing with imaging used to evaluate treatment response, … could evaluate treatment response and obviate the need for imaging would be greatly useful.

43. Coronary-Artery-Stenting Executive (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/coronary-artery-stenting_executive.pdf
    February 01, 2013 - Immediately after PCI to evaluate the success of stent placement? … Immediately after PCI to evaluate the success of stent placement? … Grading the Body of Evidence We followed the Methods Guide to evaluate the strength of the body of … Our analyses evaluate both intermediate and clinical outcomes at various time points (short, medium … FFR and IVUS are often used as complementary modalities during an intervention to evaluate different

44. Evidence Summary for Treatments for Acute Pain: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/cer-240-acute-pain-evidence-summary.pdf
    December 01, 2020 - Evidence Summary Main Points Background and Purpose The purpose of this review is to evaluate … Additionally, trials were not designed to evaluate how benefits and harms varied in subgroups. … an important clinical challenge, were often excluded from trials, and trials were not designed to evaluate

45. Respectful Maternity Care: Dissemination and Implementation of Perinatal Safety Culture to Improve Equitable Maternal Healthcare Delivery and Outcomes (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/respectful-maternity-care-protocol.pdf
    September 16, 2022 - improve outcomes, particularly for disadvantaged populations.40 The goal is to define, identify, and evaluate … We will also review and evaluate existing conceptual frameworks such as the MADM,43 MIST,12 and MOR44 … Key questions 2,3,4: We will evaluate studies of comparative effectiveness of strategies to implement … We aim to evaluate how the effective delivery and strategies to implement or provide RMC varies among … Publication Date Range: For key questions that define, measure, and evaluate effectiveness of RMC, we

46. Ced -Appendix-2 (xls file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/ced%20-appendix-2.xlsx
    May 29, 2025 - We recommend that AHRQ establish appropriate outcome measures that better evaluate advance imaging and … controlled trial), and should have the flexibility to include any research methods rigorous enough to evaluate … Can AHRQ explain the methodology used to evaluate the existing CED NCDs as well as an explanation as … to comment objectively on their strengths and limitations Can AHRQ explain the methodology used to evaluate … controlled trial), and should have the flexibility to include any research methods rigorous enough to evaluate

47. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/whitepaper3-lijmer02262010-2.pdf
    January 01, 2009 - Phase 0 studies are exploratory first-in-human trials to evaluate whether the drug or agent behaves … In 1978, Freedman classified designs to evaluate and compare imaging techniques and observed a parallel … It is inevitable that such trials evaluate the effectiveness of testing as well as that of downstream … How to evaluate a diagnostic marker test. … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do

48. PROPOSALS FOR A PHASED EVALUATION OF (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-tests-proposals_research.pdf
    January 01, 2009 - Phase 0 studies are exploratory first-in-human trials to evaluate whether the drug or agent behaves … In 1978, Freedman classified designs to evaluate and compare imaging techniques and observed a parallel … It is inevitable that such trials evaluate the effectiveness of testing as well as that of downstream … How to evaluate a diagnostic marker test. … When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do

49. Research Protocol for Interventions for Substance Use Disorders in Adolescents: A Systematic Review (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/suda-final-protocol.pdf
    October 02, 2018 - educate psychiatrists as well as primary care physicians.23 The overarching goal of the review is to evaluate … In addition, the review will evaluate treatment effects across population subgroups and identify evidence … will be We will evaluate these articles using an Evidence Map structure in which we will gather basic … We will evaluate the risk of bias factors as possible explanations for any heterogeneity. … study, patient, and intervention features, (as listed in the KQs) and to evaluate dose-response.

50. Cancer Quality-ASSIST Supportive Oncology Quality Indicator Set: Feasibility, Reliability, and Validity Testing (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-quality-indicator-testing_research.pdf
    April 01, 2010 - We could not feasibly evaluate 3 indicators because of low prevalence; 22 indicators had significant … Indicators of Supportive Treatment) Project developed evidence-based quality indicators (QIs) to evaluate … JHH/SKCCC, after abstracting 148 medical records, we concluded that we had an adequate sample to evaluate … Routine symptom screening and recording could improve capacity to evaluate outcomes. … This robust set of quality indicators can be used to evaluate the quality of supportive and end-of-life

51. Assessing the Quality of Individual Studies (ppt file)
    effectivehealthcare.ahrq.gov/sites/default/files/assessing-quality.ppt
    January 01, 2010 - When assessing the quality of an individual study, the first step is to evaluate the study design and … The second step is to evaluate design-specific sources of bias. … rate studies good, fair, or poor Requires resolution of conflicts when two reviewers independently evaluate … Based on the topic, select and apply one of several available tools that consider and explain how to evaluate

52. Amended Protocol: Interventions for Breathlessness in Patients with Advanced Cancer (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/dyspnea-protocol-amended.pdf
    May 19, 2020 - group, and prospective or retrospective cohort studies where the primary objective of the study is to evaluate … consists of cancer patients OR study does not report stratified data Interventions All studies must evaluate … Outcomes All studies must evaluate an outcome of interest as defined by KQ1-4* • We will exclude … , and prospective or retrospective cohort studies where the primary objective of the study is to evaluate … We will evaluate statistical heterogeneity among studies using an I2 statistic, and anticipate statistical

53. The Effect of Dietary Digestible Carbohydrate Intake on Risk of Cardiovascular Disease (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
    January 01, 2023 - Purpose of the Review This systematic review and meta-analysis will evaluate the Key Question (KQ) listed … Assessment of the Risk of Bias of Individual Studies We will evaluate the risk of bias of the included … We will evaluate heterogeneity between studies using I2 indicator. … We will evaluate potential publication bias by evaluating funnel plots symmetry and using statistical … patients vs surrogates),consistency of results (based on qualitative and statistical approaches to evaluate

54. Effect-Dietary-Digestible (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
    January 01, 2021 - puberty are likely sparse.15 Purpose of the Review This systematic review and meta-analysis will evaluate … Assessment of the Risk of Bias of Individual Studies We will evaluate the risk of bias of the included … We will evaluate heterogeneity between studies using I2 indicator. … We will evaluate potential publication bias by evaluating funnel plots symmetry and using statistical … patients vs surrogates), consistency of results (based on qualitative and statistical approaches to evaluate

55. EHC Research Protocol (Amended): Treatments for Acute Episodic Migraine (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-treatments-research-amended-protocol.pdf
    January 09, 2020 - Assessment of the Risk of Bias of Individual Studies: We will evaluate the risk of bias of the included … We will evaluate heterogeneity between studies using I2 indicator. … We will conduct sensitivity analyses to evaluate robustness of our findings by excluding studies with … We will evaluate potential publication bias by evaluating funnel plots symmetry and using statistical … We will use this information to evaluate applicability of the evidence to real-world clinical practice

56. The Performance of Fusion Procedures for Degenerative Disease of teh Lumbar Spine (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/lumbar-fusion-protocol.pdf
    June 20, 2024 - We will also evaluate effectiveness of specific non-surgical procedures for treatment and for predicting … NRSIs, including comparative cohort and case-control studies specifically designed to evaluate harm, … We will report risk ratios and 95% confidence intervals to evaluate associations between interventions … If sufficient numbers of RCTs (>10) are available to evaluate small sample effects, quantitative funnel … Assessing Applicability We will evaluate applicability in accordance with the AHRQ's Methods Guide39

57. Layout 1 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
    September 01, 2011 - Insufficient Insufficient data are available to evaluate the impact of DMARDs on radiological progression … Research Although DMARDs have improved health outcomes for children with JIA, few data are available to evaluate … Trials are needed to evaluate the effectiveness of DMARDs compared to conventional therapy as well as … Trials that evaluate the efficacy of treatment should be sufficiently long, with frequent assessment … Implementing more general disease-based registries could not only help assess risk but help evaluate

58. S38 (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/s38.pdf
    October 01, 2007 - A key issue in the design of trials to evaluate quality improvement interventions is the unit of randomization … UNIT OF RANDOMIZATION A first question in the design of a trial to evaluate a quality improvement intervention … Availability of a computerized claims database offers the potential to evaluate the extent to which multiple … the number of subjects by a factor equal to the design effect.13 As an example, consider a trial to evaluate … For this reason, individually randomized trials often include a run-in period to evaluate compliance

59. Evidence-based Practice Center Systematic Review Protocol (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pdf/vte-prophyalaxis_research-protocol.pdf
    March 01, 2011 - We will evaluate drugs and devices that currently are available in the United States and either are … We will also evaluate the use of antiplatelet agents, such as aspirin and clopidogrel, as well as the … This CER will evaluate the comparative effectiveness and safety of pharmacologic prophylaxis among patients … Xa inhibitors, direct thrombin inhibitors)  Mechanical devices Comparators  We will evaluate …  We will evaluate placebo- controlled studies, studies that used active controls, and uncontrolled

60. Pathak-Sen - INNOVATIONS CONFERENCE -- UK INITIATIVE: JAMES LIND ALLIANCE (pdf file)
    effectivehealthcare.ahrq.gov/sites/default/files/pathak-sen.pdf
    May 29, 2025 - Here are just some examples of the difference and the impact, very difficult to say -- to evaluate and