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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/RkeQEwKRWULreuWecXG8S-
    July 01, 2013 - Each model estimates screening effectiveness based on a different set of equations that are key in … Model F estimates cure rates that depend on sex, tumor stage, and histology. … Model S estimates the probability of lethal metastases as a function of tumor size, histology, and … Chapter 2: Birth-cohort-specific estimates of smoking behaviors for the U.S. population. … Effects of mammography screening under different screening schedules: model estimates of potential
  2. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary36/menopausal-hormone-therapy-preventive-medication-2012
    May 29, 2012 - We included estimates for individual hormone therapy regimens and excluded estimates that pooled results … For estrogen plus progestin, estimates included HRs of 0.67 (CI, 0.47 to 0.95) for hip, 0.68 (CI, 0.48 … The WHI trials met criteria for fair quality, provided most of the estimates of benefits and harms, had … These results reflect updated estimates from the WHI trials that differ from initial results for some … Updated results for other outcomes did not substantially change from initial estimates.
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-report/breast-cancer-screening-2009
    November 15, 2009 - However, it is not feasible to conduct additional trials to get more precise estimates of the mortality … The models begin with estimates of breast cancer incidence and mortality trends without screening and … The other 3 models (E, M, and W) use the BCSC data as a guide and to fit sensitivity estimates from this … Model estimates for the oldest age groups also have more uncertainty compared with estimates for ages … First, our models provide estimates of the average benefits and harms expected across a cohort of women
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/SToafQ-B-qpCqz5_Jf43wK
    March 21, 2022 - A healthcare professional estimates 10-year risk using a CVD risk estimator. 2 selectively offer
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/hepatitis-b-virus-infection-screening
    March 14, 2019 - the FDA KQ 5: Cohort studies for long-term (>5 years) clinical outcomes that report adjusted risk estimates … association between intermediate and clinical outcomes after antiviral treatment that report adjusted risk estimates
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-review79/ovarian-cancer-screening-2004
    May 15, 2004 - However, the studies for which all of these estimates are based reported small numbers of cancer cases … with false-positive rates of 0.1 percent to 0.6 percent based on 3 studies. 14 , 15 , 17 All these estimates … The HTA systematic review applied estimates … after 1 year of followup approaches 100 percent and CA 125-based screening, 80 percent; however, these estimates … The studies in which these estimates are based were not RCTs of screening, did not report mortality outcomes
  7. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer-screening-1996
    January 01, 1996 - Estimates of the sensitivity and specificity of these maneuvers depend on a number of factors, including … The ability to detect interval cancers may also vary and will affect such estimates. … Estimates from three Swedish trials using mammography alone averaged about 75%, while estimates for mammography … Specificity estimates ranged from 98.5% in the HIP trial to 83% in the Canadian NBSS 2. … Sensitivity estimates for mammography alone and for combined screening with CBE have generally been 10
  8. www.uspreventiveservicestaskforce.org/home/getfilebytoken/bC4oNwsek4uY3SJZf4S7zm
    April 01, 2022 - Aspirin Use to Prevent Cardiovascular Disease Clinician Summary of USPSTF Recommendation Aspirin Use to Prevent Cardiovascular Disease April 2022 What does the USPSTF recommend? C Grade For adults aged 40 to 59 years with an estimated 10% or greater 10-year cardiovascular disease (CVD) risk: The decision to in…
  9. www.uspreventiveservicestaskforce.org/home/getfilebytoken/rts4chTw2sVprMEF5xpMYS
    April 01, 2022 - Aspirin Use to Prevent Cardiovascular Disease Clinician Summary of USPSTF Recommendation Aspirin Use to Prevent Cardiovascular Disease April 2022 What does the USPSTF recommend? C Grade For adults aged 40 to 59 years with an estimated 10% or greater 10-year cardiovascular disease (CVD) risk: The decision to in…
  10. www.uspreventiveservicestaskforce.org/home/getfilebytoken/CC7S5LxbFmoHh5ZmMxJWkM
    February 01, 2016 - Estimates From Observational Studies Unadjusted estimates from 13 observational stud- ies included in … Estimates from other studies fall within this overall broad range. … Studies are highly heterogeneous, and estimates vary depending on the analytic approach. … Interpreting overdiagnosis estimates in population-based mammography screening. … Estimates of overdiagnosis of invasive breast cancer associated with screening mammography.
  11. www.uspreventiveservicestaskforce.org/uspstf/recommendation/genital-herpes-serologic-screening
    February 14, 2023 - precise prevalence of asymptomatic HSV-2 infection in the US is difficult to determine because prevalence estimates … blot. 6 The 2015-2016 National Health and Nutrition Examination Survey of persons aged 14 to 49 years estimates … persons. 1 , 22 Based on previous evidence from the 2016 review of 11 studies (n = 7129), 5 accuracy estimates
  12. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/latent-tuberculosis-infection-screening
    May 02, 2023 - Pooled estimates for sensitivity of the TST were 0.80 (95% CI, 0.74-0.87) at the 5-mm induration threshold … Pooled estimates for sensitivity of IGRA tests ranged from 0.81 (95% CI, 0.79-0.84) to 0.90 (95% CI, … Pooled estimates for specificity of screening tests ranged from 0.95 to 0.99. … . 14 For screening test accuracy (KQ2), separate pooled estimates of proportions were generated for … Therefore, estimates of treatment effectiveness may represent the upper bounds of effectiveness.
  13. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-c-screening
    March 02, 2020 - Across genotypes, SVR estimates were consistent when studies were stratified according to study quality … There was some variability by DAA regimen in estimates of adverse events; estimates were generally higher … Adverse event estimates were generally similar when studies were stratified according to baseline cirrhosis … evaluated in the prior review (68%-78%). 9 Although statistical heterogeneity was present in pooled estimates … Dashed lines indicate the overall measures of effect; overall estimates were from mixed-effects models
  14. www.uspreventiveservicestaskforce.org/uspstf/recommendation/aspirin-to-prevent-cardiovascular-disease-preventive-medication
    April 26, 2022 - are discussed using the terms “men” and “women,” although it is likely that CVD risk and net benefit estimates … Clinicians should recognize that predictions of 10-year CVD events using the Pooled Cohort Equations are estimates … estimation is imprecise and imperfect at the individual level, the USPSTF suggests using these risk estimates … Pooled effect estimates of studies using low-dose aspirin were also used to inform the parameters and
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/G7CCbu64mf-nCynBkHbFLA
    July 01, 2012 - We included estimates for individual hor- mone therapy regimens and excluded estimates that pooled results … For estrogen plus progestin, estimates included HRs of 0.67 (CI, 0.47 to 0.95) for hip, 0.68 (CI, 0.48 … The WHI trials met criteria for fair quality, provided most of the estimates of benefits and harms, had … These results reflect updated estimates from the WHI trials that differ from initial results for some … Updated results for other outcomes did not substantially change from initial estimates.
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/k_QR3hvh2jVSPPLu6Q6m6r
    November 13, 2022 - Estimates Figure 1. … Estimates for all-cause and cardiovascular mortality were slightly attenuated (smaller) than from the … Estimates were similar in sensitivity analyses restricted to good-quality trials, primary prevention … Estimates were also similar in sensitivity analyses restricted to trials that were not stopped early … Pooled estimates for persons older than 70 years were generally consistent with the overall pooled estimates
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/YALMYpRCoRSu9nhPFGudEm
    November 01, 2022 - preva- lence of asymptomatic HSV-2 infection in the US is difficult to determine because prevalence estimates … blot.6 The 2015-2016 National Health and Nutrition Examination Survey of persons aged 14 to 49 years estimates … persons.1,22 Based on previous evidence from the 2016 re- view of 11 studies (n = 7129),5 accuracy estimates
  18. www.uspreventiveservicestaskforce.org/uspstf/recommendation/breast-cancer--brca-testing-ovarian-cancer-screeni
    September 15, 2005 - Published reports of penetrance describe estimates of BRCA1 and BRCA2 mutations ranging from 35 percent … or those unselected for ethnicity. 1 , 13 , 14 , 18-22 Among Ashkenazi Jewish women, penetrance estimates … percent to 81 percent for breast cancer and 10 percent to 46 percent for ovarian cancer. 1 , 23-29 Estimates … Overall, the USPSTF estimates that the magnitude of these potential harms is at least small. … Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program.
  19. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/osteoporosis-screening
    June 26, 2018 - In women, pooled AUC estimates ranged from 0.65 (95% CI, 0.60-0.71; I 2 = 97.8%; 10 studies [16,780 … In men, pooled estimates of AUC from 3 to 44 studies (13,970-15,842 participants) ranged from 0.62 to … Raloxifene Pooled estimates of women followed up from 1 to 4 years and randomized to raloxifene or … b Updated pooled estimates are provided where possible; otherwise, range of AUC estimates from relevant … c Pooled estimates include men, women, and combined estimates (1 study did not provide adverse events
  20. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary1/osteoporosis-screening-june-2018
    June 26, 2018 - In women, pooled AUC estimates ranged from 0.65 (95% CI, 0.60-0.71; I 2 = 97.8%; 10 studies [16,780 … In men, pooled estimates of AUC from 3 to 44 studies (13,970-15,842 participants) ranged from 0.62 to … Raloxifene Pooled estimates of women followed up from 1 to 4 years and randomized to raloxifene or … b Updated pooled estimates are provided where possible; otherwise, range of AUC estimates from relevant … c Pooled estimates include men, women, and combined estimates (1 study did not provide adverse events

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