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www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/lung-cancer-screening
March 09, 2021 - The estimates for the range of benefits and harms across the 4 CISNET models appear in eTables 5 and … These estimates show similar patterns as those for the whole population; however, there were higher increases … The analysis estimates that screening strategies for individuals aged 50 or 55 years through aged 80
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/ZcuLSXJZXLz9Y2LECTWqVJ
November 01, 2009 - Estimates of
overdiagnosis vary from 1% to 10%. … We calculated estimates from a random-effects model
under the Bayesian data analytic framework by using … Eight studies report estimates of overdiagnosis using
different methods (16). … None of these
studies provide estimates specific to U.S. samples. … Estimates
of the magnitude of overdiagnosis vary depending on the
analytic approach used.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/aHpXYasjc3n6zhaTtoWMwK
August 01, 2016 - Pooled estimates of sensitivity and specificity of the most commonly used
test at the manufacturer’s … At higher cutpoints, pooled estimates were
95% (95% CI, 91%-97%) and 89% (95% CI, 82%-93%), respectively … Pooled estimates
of sensitivity and specificity were 99% (95% CI, 97%-100%) and
81% (95% CI, 68%-90%) … Estimates for specificity were
highly variable, ranging from 41% to 97.5%. … The pooled estimates of
sensitivity and specificity were 95% (95% CI, 91%-97%) and 89%
(95% CI, 82%-93%
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/cLuJZx55Z6ApzYv836rkSp
February 23, 2009 - decision making is strongly encouraged with individuals whose risk is close to (either above or below) the estimates
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/473PPVwoRhapCkN9SC-rue
May 18, 2021 - OBJECTIVE To provide updated model-based estimates of the benefits, burden, and harms
of colorectal cancer … 2 additional complications per 1000 persons (ranges are across
screening strategies, based on mean estimates … higher for White men com-
pared with the total population (86 vs 81 cases per 1000, respec-
tively; estimates … Because of this age
dependency, which is the result of model structure and calibration,
MISCAN estimates … Nevertheless, model-based estimates are impor-
tant because they provide patients and their clinicians
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www.uspreventiveservicestaskforce.org/uspstf/document/postmenopausal-hormone-replacement-therapy-for-primary-preve/v2-menopausal-hormone-therapy-preventive-medicatio
August 21, 2002 - We used adjusted relative risk (RR) estimates when available or calculated them when possible. … We also used population-based estimates of incidence and mortality. 22-29 We stratified event rates … Eight published meta-analyses 71-78 of breast cancer incidence provided different risk estimates. … The applicability of population estimates when risks are determined for individuals is unknown. … Our estimates do not account for racial and ethnic differences or important risk factors.
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www.uspreventiveservicestaskforce.org/uspstf/document/postmenopausal-hormone-replacement-therapy-for-primary-preve/menopausal-hormone-therapy-preventive-medication-2002-2005
August 21, 2002 - We used adjusted relative risk (RR) estimates when available or calculated them when possible. … We also used population-based estimates of incidence and mortality. 22-29 We stratified event rates … Eight published meta-analyses 71-78 of breast cancer incidence provided different risk estimates. … The applicability of population estimates when risks are determined for individuals is unknown. … Our estimates do not account for racial and ethnic differences or important risk factors.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/sQ7hREGwnBm8Wh-LEFWP4F
October 01, 2002 - We used adjusted relative risk (RR)
estimates when available or calculated them when
possible. … We
also used population-based estimates of incidence
and mortality.22-29 We stratified event rates by … Eight
published meta-analyses71-78 of breast cancer
incidence provided different risk estimates. … The
applicability of population estimates when risks are
determined for individuals is unknown. … Our
estimates do not account for racial and ethnic
differences or important risk factors.
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www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication
August 23, 2022 - Clinicians should recognize that predictions of 10-year CVD events using the Pooled Cohort Equations are estimates … CI, 0.85 to 2.25] vs 0.99 [95% CI, 0.71 to 1.39], respectively, for cardiovascular mortality), but estimates … between statin therapy and myopathy or rhabdomyolysis, although these events were uncommon, so the estimates
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www.uspreventiveservicestaskforce.org/uspstf/document/comparative-effectiveness-of-antiviral-treatment-for-hepatitis-c-virus-infection-in-adults-a-systematic-review/hepatitis-c-screening-2013
November 15, 2012 - Excluding 2 poor-quality trials had little effect on pooled estimates 24 , 30 . … for harms similar to the estimates based on all trials 21 , 30 , 31 . … Although all studies reported adjusted risk estimates, only 8 60 , 21 , 63 , 67-70 , 73 evaluated 5 … Therefore, estimates of benefit may be exaggerated, although it is not possible to determine to what … Estimates and conclusions based on small numbers of trials should also be interpreted cautiously.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/vTJ_Zj3TAkhx45wWUDtNyt
May 01, 2021 - Clinicians should recognize that pre-
dictions of 10-year CVD events using the Pooled Cohort Equations
are estimates … CI, 0.85 to 2.25]
vs 0.99 [95% CI, 0.71 to 1.39], respectively, for cardiovascular mor-
tality), but estimates … between statin therapy and myopathy or rhabdomyolysis,
although these events were uncommon, so the estimates
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www.uspreventiveservicestaskforce.org/uspstf/document/RecommendationStatementFinal/statin-use-in-adults-preventive-medication
August 23, 2022 - Clinicians should recognize that predictions of 10-year CVD events using the Pooled Cohort Equations are estimates … CI, 0.85 to 2.25] vs 0.99 [95% CI, 0.71 to 1.39], respectively, for cardiovascular mortality), but estimates … between statin therapy and myopathy or rhabdomyolysis, although these events were uncommon, so the estimates
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www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-collaborative-modeling-of-us-breast-cancer-/breast-cancer-screening-january-2016
January 11, 2016 - The model results for overdiagnosis are not directly comparable with other published estimates 8 , 63 … Eighth, the analysis did not include screening program costs or utility estimates specific to some of … Benefits and harms of mammography screening after age 74 years: model estimates of overdiagnosis. … A reality check for overdiagnosis estimates associated with breast cancer screening. … Because the models are estimating mortality reduction with actual screening, model estimates are most
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/TVsn4SVh_jtaeqSTyrz-Gp
March 09, 2021 - The estimates for the range of benefits and harms across the 4
CISNET models appear in eTables 5 and … These estimates show similar patterns as those for the whole
population; however, there were higher increases … The analy-
sis estimates that screening strategies for individuals aged 50 or 55
years through aged 80
-
www.uspreventiveservicestaskforce.org/home/getfilebytoken/k2QHcwuK4NkvxFXhvGrbwY
May 01, 2004 - However,
the studies for which all of these estimates are based
reported small numbers of cancer cases … was
estimated at 80%, with false-positive rates of 0.1%
to 0.6% based on 3 studies.15,16,18 All these estimates … of surgery, based on reports from published studies.14
Discussion
The HTA systematic review applied estimates … 6
Screening for Ovarian Cancer: Brief Evidence Update
125-based screening, 80%; however, these estimates … The studies in which these estimates are based
were not RCTs of screening, did not report
mortality outcomes
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www.uspreventiveservicestaskforce.org/uspstf/document/modeling-report/lung-cancer-screening
July 30, 2013 - Each model estimates screening effectiveness based on a different set of equations that are key in predicting … Model F estimates cure rates that depend on sex, tumor stage, and histology. … Model S estimates the probability of lethal metastases as a function of tumor size, histology, and sex … These breast and colorectal cancer estimates are solely from Model E (used in prior comparative analyses … Chapter 2: Birth-cohort-specific estimates of smoking behaviors for the U.S. population.
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www.uspreventiveservicestaskforce.org/uspstf/document/modeling-report/lung-cancer-screening-december-2013
July 30, 2013 - Each model estimates screening effectiveness based on a different set of equations that are key in predicting … Model F estimates cure rates that depend on sex, tumor stage, and histology. … Model S estimates the probability of lethal metastases as a function of tumor size, histology, and sex … These breast and colorectal cancer estimates are solely from Model E (used in prior comparative analyses … Chapter 2: Birth-cohort-specific estimates of smoking behaviors for the U.S. population.
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/6dqHx6xQGq9GUv92rZUf2q
August 01, 2022 - Statin Use for the Primary Prevention of Cardiovascular Disease in Adults
The USPSTF recognizes that clinical decisions involve more considerations
than evidence alone. Clinicians should understand the evidence but
individualize decision making to the specific patient or situation.
Clinician Summary of USP…
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www.uspreventiveservicestaskforce.org/home/getfilebytoken/Q4J7tsThw_6nwfB-p-f5Hp
March 01, 2009 - Estimates of benefits and harms, especially
at the borders of the shaded and unshaded areas, should … The estimates in Figure 2 were developed assum-
ing that the men are not currently taking nonsteroidal … The estimates in Figure 4 were devel-
oped assuming that women are not currently taking
NSAIDs and are … Estimates of benefits and harms, especially
at the borders of the shaded and unshaded areas, should … The estimates of the number of
major bleeding events were assumed to be stable within age
strata with
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www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/bacterial-vaginosis-in-pregnancy-to-prevent-preterm-delivery-screening
April 07, 2020 - Studies also reported outcomes for which pooled summary estimates could not be generated, including maternal … despite large sample sizes, the incidence of these types of events was rare, resulting in imprecise estimates … e Range of estimates across the 3 studies inconsistent for sensitivity but reasonably consistent for … j The 95% confidence region suggests reasonable precision for estimates of specificity but some imprecision … in estimates of sensitivity (eFigure 3 in the Supplement).