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  1. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/genital-herpes-screening
    December 20, 2016 - Pooled estimates of sensitivity and specificity of the most commonly used test at the manufacturer's … At higher cutpoints, pooled estimates were 95% (95% CI, 91%-97%) and 89% (95% CI, 82%-93%), respectively … Pooled estimates of sensitivity and specificity were 99% (95% CI, 97%-100%) and 81% (95% CI, 68%-90%) … Estimates for specificity were highly variable, ranging from 41% to 97.5%. … The pooled estimates of sensitivity and specificity were 95% (95% CI, 91%-97%) and 89% (95% CI, 82%-93%
  2. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/genital-herpes-screening-november-2016
    December 20, 2016 - Pooled estimates of sensitivity and specificity of the most commonly used test at the manufacturer's … At higher cutpoints, pooled estimates were 95% (95% CI, 91%-97%) and 89% (95% CI, 82%-93%), respectively … Pooled estimates of sensitivity and specificity were 99% (95% CI, 97%-100%) and 81% (95% CI, 68%-90%) … Estimates for specificity were highly variable, ranging from 41% to 97.5%. … The pooled estimates of sensitivity and specificity were 95% (95% CI, 91%-97%) and 89% (95% CI, 82%-93%
  3. www.uspreventiveservicestaskforce.org/Home/GetFileByID/3795
    May 01, 2018 - Estimates are based on benefits observed in the ERSPC trial for men aged 55 to 69 years and harms derived … choose to monitor their cancer initially and later have surgery or radiation when it progresses. ** Estimates
  4. www.uspreventiveservicestaskforce.org/Home/GetFileByToken/HV9RGq3wLyh6PyK4oxVtde
    May 01, 2018 - Estimates are based on benefits observed in the ERSPC trial for men aged 55 to 69 years and harms derived … choose to monitor their cancer initially and later have surgery or radiation when it progresses. ** Estimates
  5. www.uspreventiveservicestaskforce.org/uspstf/document/final-modeling-study18/colorectal-cancer-screening
    May 18, 2021 - Objective: To provide updated model-based estimates of the benefits, burden, and harms of colorectal … 2 additional complications per 1000 persons (ranges are across screening strategies, based on mean estimates … was higher for White men compared with the total population (86 vs 81 cases per 1000, respectively; estimates … Because of this age dependency, which is the result of model structure and calibration, MISCAN estimates … Nevertheless, model-based estimates are important because they provide patients and their clinicians
  6. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
    January 14, 2025 - Sources of heterogeneity in AUC estimates include age and population evaluated along with variation in … For these reasons, the estimates of benefits probably represent the lower bounds of screening efficacy … All estimates were calculated using the DerSimonian and Laird estimator for pooling estimates. … ): range, 0.32 to 0.89    Women aged 50 to 64 y (3 estimates): range, 0.63 to 0.75    Men (10 estimates … ): sensitivity, 53% to 95%; specificity, 37% to 72%    Women aged 50 to 64 (3 estimates): sensitivity
  7. www.uspreventiveservicestaskforce.org/uspstf/sites/default/files/inline-files/lets-talk-about-it-aspirin-cvd-prevention-guide.pdf
    April 25, 2022 - This online tool estimates a patient’s risk for developing heart disease and stroke based on factors
  8. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/hepatitis-b-virus-infection-screening
    December 15, 2020 - and evaluated clinical outcomes at 1 year or later, and cohort studies that reported adjusted risk estimates … n = 3875), 35-41 , 43 , 44 , 82 and histologic improvement (2 trials, n = 1211). 35 , 82 However, estimates … 5A ); all of the trials reporting mortality evaluated nonpegylated interferon. 23 , 25 , 31 Pooled estimates … However, across intermediate and clinical outcome comparisons, estimates of risk consistently favored … Results were generally consistent when analyses were stratified by individual drug, although some estimates
  9. www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening
    May 18, 2021 - gained than annual high-sensitivity gFOBT or sDNA-FIT every 3 years. 12 , 13 Additionally, modeling estimates … Modeling estimates that screening with sDNA-FIT annually results in additional colonoscopy burden compared … Based on averaging estimates across the 3 models, if screening were performed from ages 45 to 75 years … Personalizing age of cancer screening cessation based on comorbid conditions: model estimates of harms … See modeling report 12 , 13 for additional details and model-specific estimates. c Because of imprecision
  10. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary9/breast-cancer-screening-2009
    November 15, 2009 - Estimates of overdiagnosis vary from 1% to 10%. … We calculated estimates from a random-effects model under the Bayesian data analytic framework by using … Eight studies report estimates of overdiagnosis using different methods. 16 Estimates are derived from … Estimates of the magnitude of overdiagnosis vary depending on the analytic approach used. … These estimates are difficult to apply because, for individual women, it is not known which types of
  11. www.uspreventiveservicestaskforce.org/uspstf/procedure-manual/procedure-manual-section-6-methods-arriving-recommendation
    July 06, 2017 - (e.g., mortality). 6.5.3 General Considerations for Determining Limits on Magnitude of Benefit EstimatesEstimates from direct and indirect evidence may be included in outcomes tables in order to provide the … The Task Force usually derives qualitative, rather than precise, estimates of opportunity costs. … When outcomes tables are used to present benefits, estimates for harms will also always be presented. … Because of the uncertainty and variability in the evidence used to make these estimates, the Task Force
  12. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-section-6-methods-arriving-recommendation
    July 06, 2017 - would cause health problems (rarely 100%). 6.5.4 Conceptual Confidence Limits As previously noted, estimatesEstimates from direct and indirect evidence may be included in outcomes tables in order to provide the … The Task Force usually derives qualitative, rather than precise, estimates of opportunity costs. … When outcomes tables are used to present benefits, estimates for harms will also always be presented. … Because of the uncertainty and variability in the evidence used to make these estimates, the Task Force
  13. www.uspreventiveservicestaskforce.org/uspstf/procedure-manual/procedure-manual-appendix-viii-standardization-outcome-tables
    July 01, 2017 - Parameter estimates: Important parameters should be provided, as appropriate: Screening results (sensitivity
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/MLeu_yFpPwzcZwKG6fw5ZY
    April 26, 2022 - OBJECTIVE To provide updated model-based estimates of the net balance in benefits and harms from routine … These estimates ranged from 0.4 (95% CI, −6.1 to 6.9) to 52.4 (95% CI, 43.9 to 60.9) life-years per 1000 … Effect estimates for the use of low-dose aspirin were taken from an updated systematic review that was … Replication in other simulation models can further inform reliability of estimates. … Estimates of benefits and harms of prophylactic use of aspirin in the general population.
  15. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-appendix-viii-standardization-outcome-tables
    July 01, 2017 - Parameter estimates: Important parameters should be provided, as appropriate: Screening results
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/-qaKjceN9BTy-oh7EFwXtk
    January 14, 2025 - Sources of heterogeneity in AUC estimates include age and population evaluated along with variation in … All estimates were calculated using the DerSimonian and Laird estimator for pooling estimates. … ): range, 0.32 to 0.89 Women aged 50 to 64 y (3 estimates): range, 0.63 to 0.75 Men (10 estimates): range … to 79%; specificity, 56% to 70% Men (7 estimates): sensitivity, 62% to 89%; specificity, 36% to 74% … ) Across various thresholds: Sensitivity range: 28% to 100% (24 estimates) Specificity range: 5% to
  17. www.uspreventiveservicestaskforce.org/home/getfilebytoken/R_cAa3AjFGQ2np_aQnzQGA
    February 11, 2025 - Sources of heterogeneity in AUC estimates include age and population evaluated along with variation in … All estimates were calculated using the DerSimonian and Laird estimator for pooling estimates. … ): range, 0.32 to 0.89 Women aged 50 to 64 y (3 estimates): range, 0.63 to 0.75 Men (10 estimates): range … to 79%; specificity, 56% to 70% Men (7 estimates): sensitivity, 62% to 89%; specificity, 36% to 74% … ) Across various thresholds: Sensitivity range: 28% to 100% (24 estimates) Specificity range: 5% to
  18. www.uspreventiveservicestaskforce.org/home/getfilebytoken/cED9Pf3PNUHRUptzXQza-n
    April 01, 2016 - Hubbard, PhD Background: Estimates of risk for radiation-induced breast can- cer from mammography screening … This approach provided estimates of breast cancer incidence and mortality with and without screening … to contextualize estimates of radiation-induced breast cancer cases. … Estimates of the probability distribution of cumulative radiation dose at each age among women from the … Radiation-induced breast cancer incidence was combined with breast cancer survival estimates from the
  19. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/menopausal-hormone-therapy-preventive-medication
    December 12, 2017 - Absent meta-analytic estimates, relative risks of outcomes of interest were based primarily on a recent … publication summarizing results of the WHI trials. 15 Therefore, effect estimates might differ slightly … Strength-of-evidence grades reflect the confidence that the reviewers have that various estimates of … Estimates of RRs might differ from hazard ratios of trials presented in the text. … Estimates using 1 trial are based on the best available single study.
  20. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/menopausal-hormone-therapy-preventive-medication-december-2017
    December 12, 2017 - Absent meta-analytic estimates, relative risks of outcomes of interest were based primarily on a recent … publication summarizing results of the WHI trials. 15 Therefore, effect estimates might differ slightly … Strength-of-evidence grades reflect the confidence that the reviewers have that various estimates of … Estimates of RRs might differ from hazard ratios of trials presented in the text. … Estimates using 1 trial are based on the best available single study.

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