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  1. www.uspreventiveservicestaskforce.org/home/getfilebytoken/TkWNoq6KQb3SoZ54gscLCQ
    July 25, 2016 - and evaluated clinical outcomes at 1 year or later, and cohort studies that reported adjusted risk estimates … clinical outcomes and reported very small numbers of events, re- sulting in very imprecise estimates. … However, across intermediate and clinical outcome comparisons, estimates of risk consistently favored … (1 study, n = 233),60 and composite clinical outcomes (6 studies, n = 1311),53-57,59 although some estimates … Results were gen- erally consistent when analyses were stratified by individual drug, although some estimates
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/n4sdjxShTApRE6UxvyYuzG
    November 01, 2008 - However, these estimates may be higher than what can be expected in screened populations because the … models incorporate dif- ferent assumptions about the adenoma–carcinoma se- quence that yield different estimates … previously reported in FUBT trials was maintained in longer-term follow-up, and a recent meta-analysis estimates … The model commissioned for this evidence review estimates that the USPSTF- recommended strategies would
  3. www.uspreventiveservicestaskforce.org/uspstf/document/final-research-plan/prostate-cancer-screening
    April 28, 2016 - What do model estimates suggest about: The possible mitigation of harms of PSA-based screening for … Do model estimates of net benefit depend on patients’ values and/or preferences for various health states
  4. www.uspreventiveservicestaskforce.org/home/getfilebytoken/fbQmoAPKeBekmJ7aqmALe5
    June 01, 2014 - It is difficult to estimate the prevalence of MCI, and estimates range widely, from 3% to 42% in adults … difficult to estimate because of differences in the definition of MCI and methods used in studies; estimates … Each of these tests has reason- able performance in some studies, but estimates of sensi- tivity and … It is difficult to estimate the prevalence of MCI, and estimates range widely, from 3% to 42% in adults … Mild cognitive impair- ment: disparity of incidence and prevalence estimates.
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/JcwfLrEqaaxP6DPEQvxgUs
    February 18, 2020 - stratified participants according to a baseline global car- diovascular risk score, similar relative risk estimates … There were no clear differences in estimates of effect when the trials were stratified according to statin … 26utm_content=jama.2016.15450 without severe dyslipidemia at baseline.6 Given similar relative risk estimates … statin therapy, of which the ma- jority evaluated moderate doses; there were no clear differences in estimates … most of the trials were primarily of low to moderate doses, and there were no clear differences in estimates
  6. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening
    June 20, 2017 - Because hours of contact appeared to be a strong effect modifier, separate pooled estimates were generated … Showing DerSimonian and Laird Pooled Estimates
  7. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/obesity-in-children-and-adolescents-screening-june-2017
    June 20, 2017 - Because hours of contact appeared to be a strong effect modifier, separate pooled estimates were generated … Showing DerSimonian and Laird Pooled Estimates
  8. www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/colorectal-cancer-screening3
    October 27, 2020 - or electrolyte imbalances, particularly in older adults or those with comorbid conditions; accurate estimates … Based on averaging estimates across the three models, if screening were performed from ages 45 to 75 … Personalizing age of cancer screening cessation based on comorbid conditions: model estimates of harms … tests (e.g., Hemoccult II), although there is still uncertainty about the precision of test sensitivity estimates … See modeling report for additional details and model-specific estimates. ‡ Due to imprecision in sensitivity
  9. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/human-immunodeficiency-virus-hiv-infection-screeni
    July 05, 2005 - The point estimates and 95% CIs for NNS and NNT were based on Monte Carlo simulations.  … Several assumptions made our estimates on the benefits of screening conservative. … We calculated an overall estimate of RR TN and its corresponding 95% CI by plugging these estimates … The indicated range of estimates and variation associated with estimates were incorporated in the calculations … The point estimates and 95% CI of NNS B and NNT B were based on 1,000,000 samples.
  10. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2005
    July 05, 2005 - The point estimates and 95% CIs for NNS and NNT were based on Monte Carlo simulations.  … Several assumptions made our estimates on the benefits of screening conservative. … We calculated an overall estimate of RR TN and its corresponding 95% CI by plugging these estimates … The indicated range of estimates and variation associated with estimates were incorporated in the calculations … The point estimates and 95% CI of NNS B and NNT B were based on 1,000,000 samples.
  11. www.uspreventiveservicestaskforce.org/uspstf/recommendation/thyroid-cancer-screening
    May 09, 2017 - The rate of permanent hypoparathyroidism varied widely (15 study arms); best estimates were 2 to 6 events … per 100 total thyroidectomies, and estimates varied more with lymph node dissection. … 94,823) provided evidence for potential harms of radioactive iodine remnant ablation or therapy. 7 Estimates
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/vw-LTWCTZ_N5pAaydcNQTx
    June 21, 2016 - Multiple observations at each data point reflect estimates from different studies. … The SimCRC and MISCAN models were each simultaneously calibrated to adenoma prevalence estimates from … If test sensitivity is lower at sub- sequent rounds of screening, estimates of the benefits of screen … The most important external parameters are the test sensitivity estimates, which were varied. … Personalizing age of cancer screening cessation based on comorbid conditions: model estimates of harms
  13. www.uspreventiveservicestaskforce.org/uspstf/recommendation/ocular-prophylaxis-for-gonococcal-ophthalmia-neonatorum-preventive-medication
    January 29, 2019 - conditions, including corneal scarring, ocular perforation, and blindness. 7 There are no contemporary estimates … Historical estimates from 19th-century Europe show that gonococcal ophthalmia neonatorum was a major
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/hDZUZdx4qLNc2PjbkfWQuw
    April 01, 2016 - The models begin with estimates of breast cancer incidence (31) and ER/HER2-specific survival trends … Models E and M fit estimates from the BCSC and other data (26, 29). … Eighth, the analysis did not include screening program costs or utility estimates specific to some of … Effects of mammogra- phy screening under different screening schedules: model estimates of potential … A reality check for overdiagnosis estimates associated with breast cancer screening.
  15. www.uspreventiveservicestaskforce.org/home/getfilebytoken/pth_4-Mnau_pZubaefDvUk
    January 01, 2020 - Most of these trials began enrollment more than 30 years ago, and these estimates may not reflect the … The best estimates from randomized, con- trolled trials (RCTs) evaluating the effect of mammogra- phy … Current estimates of the magnitude of overdiag- nosis associated with mammography screening vary widely … This has re- sulted in a wide range of estimates in the available lit- erature (0% to 54%) (2, 4). … The 6 decision models reported a wide range of estimates of the magnitude of overdiagnosis associ- ated
  16. www.uspreventiveservicestaskforce.org/home/getfilebytoken/j69Hq5ALvzg74e-ngkzSep
    April 01, 2016 - Baseline Estimates of Major Bleeding Risks, by Subgroup In both trial and cohort data, bleeding rates … DISCUSSION We found relatively consistent estimates of in- creased risk for serious bleeding events … These are the estimates we provided for the companion model (16) based on a priori deci- sions to link … harms estimates to the same population and aspirin dosages used for estimating benefits. … For both types of bleeding, our pooled estimates were not statistically heterogeneous; their imprecision
  17. www.uspreventiveservicestaskforce.org/uspstf/procedure-manual/procedure-manual-section-5-modeling
    July 05, 2017 - Inputs into decision models include best estimates from evidence on the linkages between screening and
  18. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/procedure-manual/procedure-manual-section-5-modeling
    July 05, 2017 - Inputs into decision models include best estimates from evidence on the linkages between screening and
  19. www.uspreventiveservicestaskforce.org/uspstf/recommendation/statin-use-in-adults-preventive-medication-november-2016
    November 13, 2016 - There were no clear differences in estimates of effect when the trials were stratified according to statin … subgroups, including patients without severe dyslipidemia at baseline. 6 Given similar relative risk estimates … statin therapy, of which the majority evaluated moderate doses; there were no clear differences in estimates … be linear according to a patient’s absolute risk level, and any cut points used are only population estimates … most of the trials were primarily of low to moderate doses, and there were no clear differences in estimates
  20. www.uspreventiveservicestaskforce.org/uspstf/about-uspstf/methods-and-processes/use-decision-models-development-evidence-based-clinical-preventive-services-recommendations
    May 01, 2019 - demographic characteristics, such as race/ethnicity or comorbid conditions; and assess uncertainty in estimates … USPSTF gains experience with modeling analyses across a broader range of topics, the use of model-based estimates

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