-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests_executive.pdf
February 01, 2006 - ratio 0.33 NC 0.16 0.21
Negative predictive value at
20% prevalence 92.4% NC 96.2% 95.0%
Stability of estimates … likelihood ratio NC 0.41 NC NC
Negative predictive value
at 20% prevalence NC 90.7% NC NC
Stability of estimates … likelihood ratio NC NC NC NC
Negative predictive value
at 20% prevalence NC NC NC NC
Stability of estimates
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
January 15, 2016 - We have emphasized in our discussion of meta-analysis findings that the
estimates provide relative ranking … We have also noted in the report’s Conclusions that the estimates provided
are most important as relative … The estimates provide a relative ranking of anticipated
rates of lesion clearance among treatment options … Therefore, the difference
between any two estimates is the comparative effectiveness. … Peer reviewer #4 Results Figure 6, note that estimates of sigma are typically smaller
for smaller effect
-
effectivehealthcare.ahrq.gov/sites/default/files/s23.pdf
October 01, 2007 - examples of communicating benefits and harms
for well-known therapeutics, illustrating that relative risk estimates … Although the estimates might change when more information
from other studies becomes available, the public … For the most part, the articles discuss
relative estimates (relative risks or odds ratios; Fig. 1). … Relative risk estimates are not helpful for communicating
the chance of experiencing an event (either … benefit or a
harm).9,29 In our scenario, relative risk estimates cannot
accurately depict the chance
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
April 01, 2014 - Results from these studies
therefore could not be included in summary estimates for sensitivity and … specificity, resulting in
less robust and potentially biased estimates. … is obtained and how that
information affects the conclusions of the systematic review, including estimates … The additional data
enabled somewhat more robust estimates for diagnostic accuracy at commonly used … Although the effects on summary estimates were relatively small in most
cases, the changes had important
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/asthma-immunotherapy-2011_research.pdf
January 01, 2011 - Precision of the estimates 5±2
13. … Reliability of the estimates. … Reliability of the estimates. … Reliability of the estimates. … B Mean and standard error of estimates
reported
C Numeric value of estimates not
reported (
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/primary-healthcare-spending-disposition-comments.pdf
May 17, 2024 - but only mention
one (PCC) and focus primarily on state estimates. … We have clarified
the number of
reports and
estimates we
found throughout
the report. … KI Reviewer 1 General
Comments
In the abstract it says you found 3 national estimates but
elsewhere … We will
revise the text to
clarify what
estimates we are
referring to. … I believe MA also
may include this method for its non-claims estimates.
-
effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
January 01, 2013 - differences in the time window during which exposure is determined can lead to changes in study effect estimates … adjustment, may provide insight into which covariates have relatively greater influences on effect estimates … analysis is based on different assumptions than conventional approaches and may build confidence in estimates … For example, Samy Suissa (2008) illustrated how the choice of cohort definition can affect effect estimates … also consider the method of covariate adjustment to see if it might result in changes in the effect estimates
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
May 01, 2008 - is estimated that as many as 75% of all persons with
dementia will eventually reside in the NH. 7
Estimates … The aim of this project was to provide nationally representative estimates of the prevalence
of the … The
MCBS survey weights are used to project national estimates for each measure. … Data from claims provided slightly higher estimates of dementia cases
than self/proxy reports in the … Alzheimer disease in the US population:
Prevalence estimates using the 2000 census.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - Relative risk estimates were
derived from the meta-analyses and other age-specific and
race-specific … Depending on the
analysis, each model run included 5,000 to 1,000,000
simulated individuals; estimates … Decision Analysis: Benefits and
Harms of OC Use and Ovarian Cancer Risk
Using the point estimates from … of their effect on
mortality derived from a model are even more uncertain
than estimates for incident … Because
these data are cross-sectional, estimates for older women
reflect cohorts that were relatively
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - meta-analysis is appropriate (i.e., more than 2 studies address
the same PICOTS and provide point estimates … If
meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates
from … comparison have
high or unclear risk of bias or when sensitivity analyses show a substantial difference in
estimates … derived from high or unclear risk of bias studies versus estimates derived from
studies at low risk … Cardiovascular Disease Projections in the United
States Based on the 2020 Census Estimates.
-
effectivehealthcare.ahrq.gov/sites/default/files/exposure-definition-and-measurement_chapter-4.pptx
January 01, 2013 - appropriate for defining exposure
Provide evidence of validity of the operational definition of exposure with estimates … Evidence of validity may be provided by estimates of sensitivity, specificity, or positive predictive … This measurement error can result in biased estimates either away from or towards the null, making the … Evidence of validity may be provided by estimates of sensitivity, specificity, or positive predictive … Evidence of validity may be provided by estimates of sensitivity, specificity, or positive predictive
-
effectivehealthcare.ahrq.gov/sites/default/files/s149.pdf
October 01, 2007 - This
choice can lead to unstable estimates due to small sample
sizes, especially for skewed data such … Construct estimates of treatment
effects such as absolute E{Y(EEE)} � E{Y(III)}or relative
E{Y(EEE)}/ … The
outcome estimates were qualitatively similar to the results pre-
sented in the article. … However, estimates from
our methodology should approximate the upper limit of effec-
tiveness of a medication … Best estimates
of diabetes prevalence in the Department of Veterans Affairs based on
computerized patient
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - We calculated meta-estimates of the
probability of leiomyosarcoma for all relevant studies and
by study … Lack of
precision means these estimates are not credibly different. … Some recent estimates in
the literature find otherwise. … Uncertainty in estimates of prevalence and evolving data
about methods for tissue extraction and their … Our
estimates and that of Pritts and colleagues10 find that
the estimates are lower in data from more
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
September 01, 2012 - Meta-Analysis
We conducted a Bayesian meta-analysis to provide
aggregate estimates of the effectiveness … We calculated meta-analysis estimates by using RCTs
grouped by progestogen formulation (17OHP, oral, … For neonatal mortality, aggregate estimates indicated no
formulation was effective at reducing risk … However, all
formulations were effective at reducing the risk of preterm
birth (meta-estimates: OR17OHP … In general, studies have also
been too small to provide valid estimates of factors that
may modify
-
effectivehealthcare.ahrq.gov/products/choice-of-mean/white-paper
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
September 07, 2012 - As above, we find the aggregate estimates of
benefit among those with prior preterm birth to
be squarely … We take some reassurance that providing
summary evidence is sufficient since the
meta-estimates for … Meta-estimates added to results
section. … Point estimates and 95% confidence intervals
are not consistently reported. … A summary table including all meta-estimates might be
helpful.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
January 01, 2010 - were based upon Kaplan-Meier estimates for treatment-specific
censoring distributions; whereas adjusted … estimates were based upon weights that were
functions of Kaplan-Meier censoring estimates and propensity … score estimates.17,18
Adjusted hazard ratios were calculated according to the inverse probability … These models served to
validate the adjusted hazard ratio estimates from the IPW Cox regression model … Such misclassification and underreporting should be non-
differential, however, and should bias our estimates
-
effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
October 01, 2007 - of restrictions
for use in pharmacoepidemiology and examines to what extent they
change rate ratio estimates … RR estimates adjusted for age and sex also steadily
increased. … For all earlier
restrictions, it is less clear how much the observed change in
RR estimates result from … We found that this
change resulted in an observable but not substantial change in
RR estimates in our … A, Unadjusted mortality rate ratio estimates; B, Multi-
variate adjusted mortality rate ratio estimates
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
November 20, 2013 - Empirical Bayes estimates
generated in a hierarchical summary ROC analysis
agreed closely with those … For diagnostic questions this means
either ‘can the sensitivity and specificity estimates found in … or ‘do these
sensitivity and specificity estimates tell me that the patient
will benefit from this … What is the direction of
sensitivity estimates, for example? … But
sensitivity and specificity estimates lay between 0% and
100%.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - quantity of evidence, directness (or indirectness) of evidence, consistency of evidence, and precision of estimates … Includes considerations of:
Statistical significance for effect estimates
Confidence intervals for those … effect estimates
Four Required Domains: Precision
Four Required Domains: Precision
Precision is the … These estimates were consistent, direct, and precise. … Had these estimates been precise and consistent (i.e., a narrower CI for the RCT, consistent cohort studies