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effectivehealthcare.ahrq.gov/products/grades-predictive-values/abstract
September 14, 2015 - We used z-scores to compare the effect estimates of the subsets (which we term the "gradeable effect" … The predictive validity of quality of evidence grades for the stability of effect estimates was low:
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/version-2-risk-of-reinfection-from-SARSCoV2.pdf
July 01, 2022 - We examined the relationship between these
factors and protection estimates but lacked sufficient data … We subsequently found a high degree of concordance between our calculated risk
estimates and the rates … We generated uncorrected estimates for comparison. … Protection estimates (1 – RR) can be interpreted as the proportion or
percentage of infections that … Baseline Factors
Age, Sex, and Race
In the Denmark study, there was no difference in the estimates
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/version-2-risk-of-reinfection-from-SARSCoV2.pdf
July 01, 2022 - We examined the relationship between these
factors and protection estimates but lacked sufficient data … We subsequently found a high degree of concordance between our calculated risk
estimates and the rates … We generated uncorrected estimates for comparison. … Protection estimates (1 – RR) can be interpreted as the proportion or
percentage of infections that … Baseline Factors
Age, Sex, and Race
In the Denmark study, there was no difference in the estimates
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effectivehealthcare.ahrq.gov/products/incident-user-design/research
May 15, 2012 - But an incident user design also reduces the precision of comparative effectiveness estimates. … First, the confidence intervals for the estimates of comparative effectiveness may be so wide that they … The estimates of comparative effectiveness may be more valid (internally), but apply to fewer patients … Or can valid estimates of comparative effectiveness be obtained by comparison with non-users? … We lack evidence to know how much active control cohorts matter for estimates of comparative effectiveness
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/incident-user-design_research.pdf
May 01, 2012 - But an incident user design also reduces the precision of comparative
effectiveness estimates. … First, the confidence intervals for the estimates of comparative
effectiveness may be so wide that they … The estimates of comparative effectiveness may be more valid
(internally), but apply to fewer patients … Or can valid
estimates of comparative effectiveness be obtained by comparison with non-users? … We lack evidence to know how much active control cohorts matter for estimates of
comparative effectiveness
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/quantitative-synthesis-expanded-methods_methods.pdf
March 01, 2013 - Note: Vertical lines indicate the estimates for the entire set of 10 studies. … Hence the methods tend to
underestimate the error associated with parameter estimates, particularly … It is not unusual for estimates based on a
handful of early studies to shift considerably over time … for all estimates. … combined study estimates based on
the type of data and choice of effect measure.
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effectivehealthcare.ahrq.gov/sites/default/files/s16.pdf
October 01, 2007 - Effectiveness trials More representative estimates of benefits and harms in typical patients. … Systematic reviews and
meta-analyses
Pooled results may allow estimates of less frequent events and … Can identify more specific estimates of baseline risk
to help target treatment. … Administrative database Estimates of major harms across large populations; detection of rare events; … Can we similarly apply harms estimates from WHS?
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-binary-outcomes-evaluation_research.pdf
March 11, 2013 - Between-study variance estimates in univariate versus multivariate analyses
(frequentist analyses) . … Difference in the point estimates with univariate and multivariate meta-analysis
versus the number of … Between-study variance estimates in univariate versus multivariate analyses in
Bayesian analyses ... … Generally, the point estimates and the lengths of the confidence intervals are comparable using
the … (or standard errors of linear
combinations of the summary estimates in general5,11).
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effectivehealthcare.ahrq.gov/products/depression-postpartum-screening/research-protocol
March 09, 2012 - Incidence estimates for the first 3 postpartum months were up to 6.5 percent for major depression alone … Incorporating additional data published subsequently should add greater precision to these estimates … We will present summary estimates, standard errors, and confidence intervals. … observational studies or a comparison of estimates of the association between a history of intimate … Specific benefits include estimates of treated depression, maternal and infant health care visits, and
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_executive.pdf
February 01, 2012 - For example, if a clinician
estimates a woman’s risk of malignancy as greater than
50 percent, most … Therefore, we used the
estimates of accuracy and various clinical scenarios to
address the implicit … These estimates of accuracy
were all judged to be supported by a low strength of
evidence. … Improving the precision of the estimates of accuracy
or upgrading the strength of evidence rating in … Information from more
granular groupings of women will allow estimates of test
accuracy to be more
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effectivehealthcare.ahrq.gov/products/depression-knowledge-gaps/research
January 01, 2005 - Investigating differences in treatment effect estimates between propensity score matching and weighting
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c_executive.pdf
November 01, 2012 - Relative risk
estimates ranged from 1.01 to 1.33 in the four trials and may
have varied in part due … Relative risk estimates ranged from 0.89 to 1.2.
Moderate
11
Table A. … for SVR in men vs. women, and no clear
difference in relative risk estimates for Black vs. non-Black … Three trials that restricted enrollment to patients with genotype
1 infection reported risk estimates … for risk of harms that were
similar to the risk estimates based on all trials.
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effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
January 03, 2012 - Often these assumptions
are reasonable and, even when violated, may result
in unchanged effect estimates … Alternately, effect estimates may vary with changes
in the outcome definition. … Samy Suissa illustrated how the choice of cohort
definition can affect effect estimates in his
paper … If
there is an impact on the estimates for this sort of
transformation, it can make sense to try a … The example
estimates the association between different
statin medications with this biomarker.
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effectivehealthcare.ahrq.gov/sites/default/files/ch_10-user-guide-to-ocer_130129.pdf
January 01, 2011 - selection procedure to use,
whether to base selection upon p-values or change
in exposure parameter estimates … stepwise regression has limitations
that can lead to underestimation of standard
errors for exposure estimates … However, the
DRS estimates the probability or rate of disease
occurrence as a function of the covariates … treatment effects across individuals
also are commonly employed to obtain causally
interpretable estimates … If subjects with missing data differ
from subjects with complete data, then exposure
estimates may
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
April 01, 2012 - Adults Taking
Cardiovascular Drugs
Executive Summary
Background
The American Heart Association
estimates … Do the effect estimates of clinical cardiovascular
outcomes vary by age, ethnicity, gender, or health … Do the effect estimates of harms outcomes vary by age,
ethnicity, gender, or health status?
b. … Do the effect estimates of pharmacokinetic outcomes
vary by age, ethnicity, gender, or health status … • The study reported effect estimates that did not reflect
a comparison of supplement plus drug(s
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-executive-summary.pdf
December 01, 2023 - Insufficient
Self-help
intervention
Quality of life Both studies reported positive
effects, but the estimates … effect
Other: Writing
and Music
Grief symptoms Both studies reported positive
effects, but the estimates … : Integrative
Medicine
Grief disorder symptoms Both studies reported positive
effects, but the estimates … : Integrative
Medicine
Grief disorder symptoms Both studies reported positive
effects, but the estimates
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-balancing-harms-benefits_research-2012.pdf
January 01, 2012 - Comparisons The estimates of effect from a study may reflect the beneficial effect of one intervention … concerning harm tend to have more uncertainty
compared with estimates of benefit. … The fifth step consists of
sensitivity analyses to explore the effects of changing the estimates or … However, the ―T‖ score has no uncertainty
estimates. … The reviewers need
to indicate the time periods that relate to the estimates.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/statistical-inference_research.pdf
April 01, 2013 - Estimates of sampling variance for the SMD ES in the one-group design with
repeated-measures ..... … Estimates of sampling variances for the SMD ES from two-group designs with
repeated-measures ...... … Moreover, it is also important to know the best
estimates of within-subjects ESs (in single- and in … Estimates of sampling variance for the SMD ES in the one-group design with repeated-measures
No. … Estimates of sampling variances for the SMD ES from two-group designs with repeated-measures
No.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-258-diagnostic-errors-summary.pdf
December 01, 2022 - estimates. … present 95 percent confidence
intervals (CIs); otherwise, we present plausible range (PR) bounds for key estimates … Preventable harm rate estimates derived from two studies conducted at academic centers
(1 in Canada, … Studies of disease-specific error rates were sufficient for meta-analysis (n=6) or at least
point estimates
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effectivehealthcare.ahrq.gov/products/dementia-databases-methods/research
May 22, 2008 - Abstract
Objectives: To establish nationally representative estimates of the use of agents to treat … The aim of this project was to provide nationally representative estimates of the prevalence of the use … The MCBS survey weights are used to project national estimates for each measure. … Data from claims provided slightly higher estimates of dementia cases than self/proxy reports in the … Alzheimer disease in the US population: Prevalence estimates using the 2000 census.