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effectivehealthcare.ahrq.gov/sites/default/files/pdf/telehealth-acute-chronic_research-protocol.pdf
February 15, 2017 - sufficient data are available, meta-analyses will be conducted to summarize data and obtain
more precise estimates … evidence gaps using value of
information (VOI) analysis, which can help provide decision makers with estimates
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/labor-dystocia_research-protocol.pdf
July 28, 2016 - 18
One potentially important consideration is the effect of changing diagnostic thresholds on
estimates … This
in turn could have substantial impact on the precision of effect estimates, as well as on
estimates … We will present summary estimates, standard errors, and
confidence intervals. … Because of the risk of unmeasured confounding, observational
studies would generally not contribute to estimates
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/stroke-atrial-fibrillation_executive.pdf
August 01, 2013 - Summary of strength of evidence and c-statistic estimates for KQ 1
(discrimination of thromboembolic … Summary of strength of evidence and c-statistic estimates for KQ 2
(discrimination of bleeding risk … Summary of strength of evidence and effect estimates for KQ 3
(interventions for preventing thromboembolic … Summary of strength of evidence and effect estimates for KQ 3
(interventions for preventing thromboembolic … Summary of strength of evidence and effect estimates for KQ 3
(interventions for preventing thromboembolic
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - the
precision of the estimate of effect (based on the number
and size of studies and CIs for the estimates … In one study, estimates of opioid misuse
were lower based on independent review than based on
assessments … In three studies of the ORT, estimates
were extremely inconsistent (sensitivity ranged from 0.20 … Like a previous systematic
review, we found variability in estimates of abuse and
related outcomes, … with some potential differences in
estimates based on clinical setting (primary care versus
pain clinic
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
May 01, 2021 - Despite pooling data across
studies, confidence intervals around risk estimates were often wide due
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/bereaved-persons-protocol.pdf
June 01, 2023 - We will report point estimates together with 95 percent confidence
intervals. … Where studies cannot be combined statistically, we will convert to measure-
independent effect estimates … using the Begg and the Egger test.41, 42 The trim and fill method will be used to
provide alternative estimates
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amendment.pdf
May 02, 2025 - If network meta-analytic
estimates are used, we will consider the weight of direct versus indirect evidence
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
May 29, 2025 - Title
Addendum Appendix - Evidence Table
Table1. Evidence Table Addendum
Table 1. Evidence table for a randomized controlled trial evaluating external beam radiation therapy for the palliative treatment of metastatic bone disease identified after submission of final report and summarized in …
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/insomnia_protocol-140716.pdf
April 03, 2014 - respiratory disease, rheumatic disease, cardiovascular disease,
cerebrovascular conditions, and diabetes.2
Estimates … function, mood disturbance, and distress or interference with personal
functioning.1, 6
Prevalence estimates … Estimates
range from nearly 33 percent in an international sample of primary care patients to 17
percent
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/insomnia_research-protocol.pdf
April 03, 2014 - disease, rheumatic disease, cardiovascular disease,
cerebrovascular conditions, and diabetes.2
Estimates … function, mood disturbance, and distress or interference with personal
functioning.1, 6
Prevalence estimates … Estimates
range from nearly 33 percent in an international sample of primary care patients to 17
percent
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/prostate-cancer_executive.pdf
February 01, 2008 - When reported, there was
extremely wide variation within and between
treatments, making overall estimates … It was not possible to provide
precise estimates regarding comparative effectiveness or
specific AEs … Additional estimates for U.S. population-based AEs at 5
years following treatment were obtained from … Estimates from large ongoing screening trials suggest
that PSA increases the time of detection by 5-15 … Identification of biomarkers to provide reliable
estimates about prostate cancer aggressiveness and the
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/radiation-therapy-brain-metases-protocol.pdf
October 10, 2019 - effect sizes for
the direct comparisons and compare results with the indirect network comparison
estimates … intervention, and comparator combinations can be found, we will list the
individual study’s point estimates … .79
Where publication bias is indicated, we will use the trim and fill method to provide
adjusted estimates … • Medium
• Low
• Insufficient evidence
The categories communicate the confidence in the summary estimates … Key results that are based on measure-independent effect estimates, such as relative risks
or standardized
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
June 01, 2010 - cost of treatment.10 The cost of a typical 17-OHP
treatment regimen is relatively modest; one study estimates … Estimates of the cost and length of stay changes that can be
attributed to one-week increases in gestational
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/migraine-emergency_research-protocol.pdf
July 18, 2011 - software (Medical Research
Council Biostatistics Unit, Cambridge, United Kingdom) to obtain simultaneous estimates … of all
interventions compared with placebo, as well as estimates of which interventions are the best … A burn-in sample of 20,000 iterations, followed by 200,000 iterations, will be used to compute
estimates
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/medical-evidence-communication_research-protocol.pdf
July 31, 2012 - Overall strength
of evidence
The strength of the evidence represents the degree of confidence that the estimates … Evidence lacking consistency includes
studies with greatly differing or conflicting effect estimates … We will
also exclude studies that compare alternate presentations of point estimates, as these studies … by calculating the chi-squared statistic and the I2 statistic (the
proportion of variation in study estimates … Communication of uncertainty regarding individualized
cancer risk estimates: effects and influential
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-off-label-update_research-protocol.pdf
May 19, 2010 - Evidence Report on the
Source: www.effectivehealthcare.ahrq.gov
Published Online: May 19, 2010
Evidence-based Practice Center Systematic Review Protocol
Project Title: Efficacy and Comparative Effectiveness of Off-Label Use of Atypical
Antipsychotics – Update
I. Background and Objectives for the Sys…
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/binge-eating_clinician.pdf
May 01, 2016 - Management and Outcomes of Binge-Eating Disorder in Adults: Current State of the Evidence
Management and Outcomes of Binge-Eating Disorder
in Adults: Current State of the Evidence
Focus of This Summary
This is a summary of a systematic review evaluating the evidence regarding the effectiveness, comparative effectiv…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
February 01, 2016 - Pharmacotherapy for Adults With Alcohol Use
Disorder (AUD) in Outpatient Settings
Focus of This Summary
This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and adverse effects
of medications in adults with alcohol use disorder (AUD). The systematic revi…
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_research-protocol.pdf
June 12, 2014 - For example,
in assessing the precision of estimates of test performance, it may be difficult to judge
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_clinician.pdf
August 01, 2016 - Contrast-Induced Nephropathy (CIN): Current State of the Evidence on Contrast Media and Prevention of CIN
Focus of This Summary
This is a summary of two systematic reviews. One review evaluated the evidence regarding the comparative effects of
different contrast media in patients requiring diagnostic imaging studies…