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Showing results for "estimates".

201. Disposition of Comments Report for Comparative Effectiveness Review 128 Oral Mechanical Bowel Preparation for Colorectal Surgery (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
     April 30, 2014 - However, valid estimates of treatment effects are ideally obtained from randomized trials. … In the Final Report we have clarified how these estimates were obtained and have clearly indicated … I realize you would have to go beyond the ORs to make such estimates. … ” analysis can produce better estimates of heterogeneity (and consequently, better estimates of effect … are low, most estimates are close to 1).

202. Disposition of Comments Report for CER 207 on PTSD (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
     May 17, 2018 - I2 = 0%, visual inspection of the Forest plot demonstrates clear homogeneity of the point estimates … We agree that the calculated I-squared indicated homogeneity of the estimates, but we do not believe … from the 2013 report for some treatments for some outcomes but having no summary estimates for even … We have modified to presenting MA pooled estimates when the evidence included at least 3 studies of … Thus, all estimates of direct comparisons between two drug treatments are based on placebo comparisons

203. Acs-Pci-Adjunctive-Devices Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/acs-pci-adjunctive-devices_research-protocol.pdf
     July 01, 2010 - Source: www.effectivehealthcare.ahrq.gov Published Online: July 01, 2010 1 Evidence-based Practice Center Systematic Review Protocol Project Title: Comparative Effectiveness of Adjunctive Devices to Remove Thrombi or Protect Against Distal Embolization in Patients with Acute Coronary Syndrome Undergoing P…

204. Integrating Bodies of Evidence: Existing Systematic Reviews and Primary Studies (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/integrating-evidence_methods.pdf
     February 01, 2015 - precision, directness and reporting bias), review authors should consider how new evidence would change estimates … approaches for combining new studies with the summary estimate from prior meta-analyses versus with estimates … As new methods are developed or old methods questioned, when are the prior estimates no longer considered … For instance, if the prior review used DerSimonian-Laird model,19 do new summary estimates need to … models for meta-analysis were used, are there standards that can be established for when the prior estimates

205. Mrsa-Screening-2010 Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/mrsa-screening-2010_research-protocol.pdf
     January 01, 2010 - When small differences occur in quantitative estimates of data from published figures, the values … will be obtained by averaging the estimates of the two reviewers. … When small differences occur in quantitative estimates of data from published figures, the values … will be obtained by averaging the estimates of the two reviewers. … will be obtained by averaging the estimates of the two reviewers.

206. Untitled (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/autism-medical-update_research-protocol.pdf
     February 16, 2016 - States is 14.7 cases per 1,000 children living in the communities surveyed, or 1 in 68, with rate estimates … We will summarize data related to core and associated symptoms with estimates of treatment effects and … Newer approaches to random effects meta-analysis allow for robust (e.g., non-parametric) estimates … domains of consistency and precision will be assessed based on the direction and variation of the estimates … Cost-benefit estimates for early intensive behavioral intervention for young children with autism—general

207. Venous-Ulcers-Treatment-Future Research (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/venous-ulcers-treatment-future_research.pdf
     January 01, 2014 - Future Research Needs Num Paper ber 34 Chronic Venous Leg Ulc Treatment: Future er Research Needs Future Research Needs Paper Number 34 Chronic Venous Leg Ulcer Treatment: Future Research Needs Identification of Future Research Needs From Comparative Effectiveness Review No. 127 Prepared for:…

208. Covariate Selection for Observational Comparative Effectiveness Research
     effectivehealthcare.ahrq.gov/sites/default/files/covariate-selection-chapter-7.pptx
     January 01, 2013 - Effects of adjusting for instrumental variables on bias and precision of effect estimates.

209. Evidence Report on the (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/crohns-disease_research-protocol.pdf
     September 01, 2010 - identifying all paths that contribute to the indirect comparisons and calculation of their effects estimates … This analysis will also generate the point estimates and measure of heterogeneity for each direct comparison … www.effectivehealthcare.ahrq.gov Published Online: September 01, 2010 inconsistency, we will provide direct and indirect estimates … determine whether there is important inconsistency we will test differences between direct and indirect estimates

210. Slide 1
     effectivehealthcare.ahrq.gov/sites/default/files/study-size-planning-chapter-9.pptx
     January 01, 2013 - It is recommended that estimates of standard deviations and event rates be taken from existing literature

211. Ch 3-User-Guide-To-Ocer 130129 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
     September 21, 2012 - 35 Abstract Patient populations within a research study are heterogeneous. That is, they embody characteristics that vary between individuals, such as age, sex, disease etiology and severity, presence of comorbidities, concomitant exposures, and genetic variants. These varying patient characteristics can potentiall…

212. Noninvasive, Nonpharmacological Treatment for Chronic Pain (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/nonpharma-treatment-pain_research-protocol-amended.pdf
     September 20, 2017 - Do estimates of benefits and harms differ by age, sex, or presence of comorbidities (e.g., emotional … Meta-analyses will be conducted to summarize data and obtain more precise estimates on primary outcomes … Random effects across studies are assumed and if estimates across studies vary widely, profile likelihood … will be used to combine studies to account for uncertainty across them and provide more conservative estimates … the pooled estimate, and the likelihood that results from new studies would impact conclusions and estimates

213. S81 (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/s81.pdf
     October 01, 2007 - The median point estimates of various performance characteristics were as follows: ESS � 0.84 (range, … In this analysis, the median point estimates of various performance characteristics were as follows:

214. Clopidogrel after Drug-Eluting Stent Implantation: Is current practice sufficient (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/stent-clopidogrel-practice_research.pdf
     March 01, 2009 - weighted estimators were based on partitioning the data into monthly intervals. 13 Unadjusted estimates … were based on weights that are a function of Kaplan-Meier estimates for the treatment-specific censoring … Inverse probability weighted adjusted estimates were based on estimated propensity scores and Cox proportional … hazards estimates of the treatment-drug group specific censoring distributions. 16 SAS PROC GENMOD

215. Infantile-Hemangioma Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_executive.pdf
     January 01, 2016 - Further research is unlikely to change estimates. … Estimates of expected IH clearance Note: Estimates of expected IH clearance are expressed as percent … Estimates did not differ markedly when poor quality studies were removed, though BCI typically widened … The resulting estimates were similar to those of the model fit to all studies, but with much wider … Since there was no obvious systematic bias due to study design, we reported the model estimates based

216. Antibody Response Following SARS-CoV-2 Infection and Implications for Immunity: Final Update of a Rapid, Living Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
     December 31, 2022 - was that Omicron was less likely to cause serious disease than previous variants.39, 41, 42 Current estimates … Third, most studies were small (fewer than 200 participants), leading to lack of precision in estimates … rated the overall Strength of Evidence (SoE) for each outcome to describe our confidence in effect estimates … , and (4) ascertainment of cases during follow-up, and evaluated the impact on risk of reinfection estimates … As this makes the estimates from the new studies qualitatively different from those in the original

217. Menopause Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopause_executive.pdf
     March 01, 2015 - For Key Question 1, standardized mean differences were calculated from reported estimates of treatment … Effect estimates and accompanying 95% credible intervals were obtained from the samples. … To evaluate consistency, we compared available pairwise estimates with the network results16 and explored … Pooled estimates should be interpreted with this understanding. … The closeness of most network and pairwise estimates shows that inconsistencies are likely small.

218. Research White Paper Managing Missing Data in Patient Registries Addendum Registries for Evaluating Patient Outcomes Third Edition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/missing-data-registries-guide-3rd-ed-addendum-white-paper.pdf
     February 01, 2018 - Missing Data in Patient Registries When the data are MCAR, complete case analysis produces unbiased estimates … In either case, the precision of the estimates from a complete case analysis will be reduced due to … example, but single imputation will in any case be anti-conservative with respect to precision of effect estimates … model for the missingness process; as such multiple imputation is very unlikely to result in biased estimates … Under the assumption of MAR, MLE is efficient and provides unbiased estimates.

219. Antipsychotics for the Prevention and Treatment of Delirium: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
     June 01, 2018 - If we see substantial heterogeneity (I-squared > 50%) in pooled estimates for any outcome, we will … heterogeneity among studies with an I-squared statistic, which describes the variability in effect estimates

220. Dietary Saturated Fat Replacement and Plasma Lipid and Cardiovascular Events (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/saturated-fat-replacement-protocol.pdf
     January 01, 2024 - measurement, analysis plan),17 in addition to questions related to the likely accuracy of dietary intake estimates … directness of the evidence to the Key Question, the consistency of study results, the precision of any estimates … Outcomes with highly imprecise estimates (e.g., with 95% confidence intervals that extend beyond both