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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/acute-pain-ems-protocol-amendment.pdf
    January 28, 2019 - The prevalence of pain specifically in the prehospital setting varies, with estimates ranging from 20 … Evidence overview tables will include effect estimates and confidence intervals where quantitative … Overall conclusions and SOE will be assessed considering how the effect estimates and the confidence
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/child-obesity-future_research.pdf
    March 31, 2010 - Future Research Needs for Childhood Obesity Prevention Programs Future Research Needs Paper Number 31 Future Research Needs for Childhood Obesity Prevention Programs Future Research Needs Paper Number 31 Future Research Needs for Childhood Obesity Prevention Programs Identification of Future Resea…
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prostate-cancer-therapies-update_clinician.pdf
    January 01, 2016 - Therapies for Clinically Localized Prostate Cancer Therapies for Clinically Localized Prostate Cancer Background A National Institutes of Health (NIH) panel that convened in 2011 recommended that AS—a strategy with curative intent that involves regular monitoring of PSA levels and repeat biopsies—should be offer…
  4. effectivehealthcare.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-protocol.pdf
    December 20, 2019 - Meta-analyses will be conducted if possible to combine data and obtain more precise estimates on outcomes … for which studies are homogeneous enough to provide meaningful pooled estimates.6 The decision to conduct
  5. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-abnormalities-tests-update_research-protocol.pdf
    July 01, 2010 - Breast cancer is the second most common malignancy of women.2 The American Cancer Society estimates … typically were of lower methodological quality and that excluding them had little effect on effect size estimates … without a contrast agent to the accuracy of ultrasound with a contrast agent, if the sensitivity estimates … Precision may be rated separately for summary estimates of sensitivity and specificity for each major … tests, the conclusion will be rated as being “precise” if the confidence intervals around the summary estimates
  6. effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
    May 01, 2016 - Core-Needle Biopsy for Breast Abnormalities Core-Needle Biopsy for Breast Abnormalities Clinical Issue About one in eight women in the United States will develop invasive breast cancer during her lifetime. Approximately 290,000 new cases of breast cancer are diagnosed each year in the United States, and more than…
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician-2016.pdf
    January 01, 2016 - Behavioral Programs for Type 1 Diabetes Mellitus: Current State of the Evidence Behavioral Programs for Type 1 Diabetes Mellitus: Current State of the Evidence Focus of This Summary This is a summary of a systematic review evaluating the evidence about the effectiveness of behavioral programs for type 1 diabete…
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_clinician.pdf
    October 01, 2015 - Transitional Care Interventions To Prevent Readmissions for People With Heart Failure Focus of This Summary This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and harms of transitional care interventions (defined in Table 1) that aim to reduce readmiss…
  9. effectivehealthcare.ahrq.gov/sites/default/files/prostate-cancer-therapies-summary.pdf
    September 01, 2020 - Background and Purpose The American Cancer Society estimates that, in 2020, prostate cancer will be … • Varying thresholds to define effect size estimates may alter certainty of evidence and clinical
  10. effectivehealthcare.ahrq.gov/sites/default/files/pdf/dietary-supplements_research-protocol.pdf
    December 15, 2010 - The Magnitude of the Problem: The American Heart Association estimates that more than 81 million American … Dietary supplements have become popular for treatment and prevention of illness, with estimates suggesting … Do the effect estimates of intermediate cardiovascular outcomes vary by age, ethnicity, gender, or … Do the effect estimates of harms outcomes vary by age, ethnicity, gender, or health status? b. … Do the effect estimates of pharmacokinetic outcomes vary by age, ethnicity, gender, or health status
  11. effectivehealthcare.ahrq.gov/sites/default/files/study-eligibility-criteria.ppt
    January 01, 2000 - Does the inclusion of grey literature influence estimates of intervention effectiveness reported in meta-analyses … maternal-fetal surgery, the purpose was to describe the state of the literature, rather than to present estimates … Does the inclusion of grey literature influence estimates of intervention effectiveness reported in meta-analyses
  12. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-3-acute-pain.xlsx
    May 29, 2025 - E-1. KQ1 RCTs Table E-1. Key Question 1: Acute back pain treatment trials Author, Year (Appendix C Has Full Citations of Included Studies) Setting Country Specific Pain Condition Radiculopathy Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized N Anal…
  13. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-acute-pain.xlsx
    May 29, 2025 - E-1. KQ1 RCTs Table E-1. Key Question 1: Acute back pain treatment trials Author, Year (Appendix C Has Full Citations of Included Studies) Setting Country Specific Pain Condition Radiculopathy Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized N Anal…
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-rept-1-acute-pain.xlsx
    May 29, 2025 - E-1. KQ1 RCTs Table E-1. Key Question 1: Acute back pain treatment trials Author, Year (Appendix C Has Full Citations of Included Studies) Setting Country Specific Pain Condition Radiculopathy Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized N Anal…
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-learning-objectives-recommendations.pdf
    July 01, 2019 - A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_policymaker.pdf
    August 01, 2016 - Transitional Care Interventions To Prevent Readmissions for People With Heart Failure B A C K G R O U N D Heart failure (HF) is a major clinical and public health problem and a leading cause of hospitalization and health care costs in the United States. Despite a decline in HF-related hospitalizations during the …
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
    May 01, 2014 - Meta-analyses will be conducted to summarize data and obtain more precise estimates on outcomes for
  18. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement-may-2025.pdf
    January 01, 2025 - meta-analysis is appropriate (i.e., more than two studies address the same PICOTS and provide point estimates … We will lower SOE grading when sensitivity analyses (1) show substantial difference in estimates derived … from high or unclear risk of bias studies versus estimates derived from studies at low risk of bias
  19. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-draft-protocol.pdf
    March 14, 2024 - meta-analysis is appropriate (i.e., more than two studies address the same PICOTS and provide point estimates … We will lower SOE grading when sensitivity analyses (1) show substantial difference in estimates derived … from high or unclear risk of bias studies versus estimates derived from studies at low risk of bias
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/suicidal-thoughts-young-people-amendement.pdf
    February 05, 2025 - meta-analysis is appropriate (i.e., more than two studies address the same PICOTS and provide point estimates … We will lower SOE grading when sensitivity analyses (1) show substantial difference in estimates derived … from high or unclear risk of bias studies versus estimates derived from studies at low risk of bias

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