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effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
September 02, 2016 - Background
Selective reporting can bias estimates of effect, yet methods to detect such biases are … The overall goal of this project is to determine whether selective reporting introduces biased
estimates … Therefore, our project coordinator will send
weekly queries to co-investigators asking for estimates … These estimates will be tracked in an excel spreadsheet.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-1_research.pdf
February 01, 2009 - data and although the overall and age-stratified changes in patterns of
medication use were similar, estimates … Given the body of evidence supporting the
benefits of DMARD therapies, these estimates would suggest … In contrast to
previous estimates of DMARD utilization that were based on prevalence of use at any time
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_executive.pdf
July 01, 2012 - For KQ 1, we used a random-
effects model to compute summary estimates of effect
for hospitalizations … Summary estimates were calculated
9
using Comprehensive Meta-Analysis software and are
reported … provided for outcomes overall (incorporating evidence from all studies), while magnitude-of-effect estimates … 1 RCT and 1 observational study—reported only total costs and so did not
inform the summary effect estimates
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - There sometimes is heterogeneity in estimates of treatment effect between RCTs and NRSIs. … Moreover, because of their generally large
sample sizes, effect size estimates from individual NRSIs … and
confidence intervals, and if they are generally consistent with RCT effect estimates and
confidence … and confidence intervals, in most instances, reviewers should avoid meta-analyzing
estimates across … Effect
Estimates in Randomized Trials and
Observational Studies: Comparing Apples
With Apples.
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - There sometimes is heterogeneity in estimates of treatment effect between RCTs and NRSIs. … Moreover, because of their generally large
sample sizes, effect size estimates from individual NRSIs … and
confidence intervals, and if they are generally consistent with RCT effect estimates and
confidence … and confidence intervals, in most instances, reviewers should avoid meta-analyzing
estimates across … Effect
Estimates in Randomized Trials and
Observational Studies: Comparing Apples
With Apples.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/meditation_executive.pdf
January 01, 2014 - scores for those time
points, some of the estimates that did not account for
baseline differences … appeared to favor a different group
(e.g., treatment or control) when compared with the
estimates that … Footnote b: Magnitude—This is the range of estimates across all trials in a particular domain based on … This is a simple range of estimates, not a meta-analysis. … Both analytic methods—the difference-in-change
estimates (which accounted for baseline differences
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_disposition-comments.pdf
June 07, 2013 - We agree that, ideally, we would have estimates on
long-term cause-specific mortality for stroke, MI … Page 62 - given the number of
simulations, why not include credible intervals around the
estimates … First, it
allows the model to incorporate both the range of
uncertainty in parameter estimates (e.g … Two studies were excluded “for not reporting
point estimates for ever/never use” – but ever/never use … That is, if they
met eligibility criteria and provided other estimates of
the effects of OC use on
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/uterine-fibroids_research-protocol.pdf
March 01, 2016 - These random effects will allow estimates
of overall (population) effects as well as an estimate of … such as latent Dirichlet process and Gaussian process models, allow for
robust (e.g., non-parametric) estimates … meta-analytic model without either discarding them unnecessarily or allowing them to
influence meta-estimates … domains of consistency and precision will be assessed based on the
direction and variation of the estimates
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - vertical) transmission is believed to be
the main route of HCV infection acquisition in children.44
Estimates … a few studies and the summary
range highlighted the greater variability (and uncertainty)
in the estimates … the
estimate of effect, based on the number and size of studies
and confidence intervals for the estimates … Estimates of serious
harms associated with liver biopsy are also consistent
with estimates from the … The applicability of estimates of serious
harms such as bleeding from such studies to a screen-
detected
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research-2013.pdf
January 01, 2013 - Ignoring missing data or correlation between outcomes can produce biased MTC
estimates leading to high … Estimates of treatment effects and Best12 probabilities from four models with outcome
pain ......... … Estimates of treatment effects and Best12 probabilities from four models with outcome
disability ... … In this case, ignoring the missing treatment arms can potentially
lead to biased parameter estimates … Figure 7 displays the same density plots as in Figure 6, but under
models deliver unbiased estimates
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_disposition-comments.pdf
February 13, 2012 - non-palpable, and therefore the estimates of accuracy cannot, in most
cases, be reported separately … for different types of lesions; in the body
of the text, where possible, we did report estimates of … studies generally did not report data separately for palpable vs. non-
palpable, and therefore the estimates … separately for different types of lesions; in the body
of the text, where possible, we did report estimates
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effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - The estimates from three
studies are more stable than those from two studies,
though the number of … Did the studies
provide adjusted estimates for effect size? … If there are adjusted estimates, they
should be used. … Peer Reviewer 9 Results I would like to see the estimates of variance
parameters and its 95% CrI in … considering precision of effect estimates but
also directness, study limitations etc.) and
magnitude
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - The estimates from three
studies are more stable than those from two studies,
though the number of … Did the studies
provide adjusted estimates for effect size? … If there are adjusted estimates, they
should be used. … Peer Reviewer 9 Results I would like to see the estimates of variance
parameters and its 95% CrI in … considering precision of effect estimates but
also directness, study limitations etc.) and
magnitude
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-biopsy-update_executive.pdf
September 01, 2014 - Sensitivity estimates were higher than 0.90 and
specificity estimates were higher than 0.91 for all … However, there was substantial uncertainty
around the relative test performance estimates of the two … Results were rather imprecise (e.g., CrI widths
were often wider than 0.1) for all estimates except … Summary estimates of test performance for alternative core needle biopsy
methods— women at high risk … Summary estimates of underestimation rates for alternative core needle biopsy
methods—women at average
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/nppv-respiratory-failure_executive.pdf
July 01, 2012 - the EGRET® software (EGRET
for Windows, 1999; Cytel Software Corporation,
Cambridge, MA), which estimates
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/recombinant-factor-viia_disposition-comments.pdf
June 01, 2010 - Estimates that cross the null may be relatively precise or
relatively imprecise. … Results Figure 19-20: the marker and the bars for point estimates and 95% CIs
are not clear. … Results It is unclear from the Draft Report how the estimates for the 6,000
acute care hospitals in … but it claims that its database provides nationally representative
estimates. … The American Heart Association (AHA) estimates that the incidence of
intracerebral hemorrhagic is 10%
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/infantile-hemangioma_policymaker.pdf
June 01, 2016 - Management of Infantile Hemangioma
B A C K G R O U N D
Infantile hemangioma (IH) is generally a benign vascular
neoplasm. The International Society for the Study of Vascular
Anomalies (ISSVA) classifies IH lesions as vascular tumors,
which are differentiated from vascular malformations.2 IH affects
4 to 5 perce…
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/depression-brain-injury_executive.pdf
April 01, 2011 - emergency
department visits each year, with 1 in 4 patients
requiring hospitalization.5 Because most estimates … The Centers
for Disease Control and Prevention estimates that up to
75 percent of TBIs are mild in terms … Nonetheless, estimates of direct and indirect costs
associated with TBI exceed $56 billion each year.6 … and long-
term outcomes, including physical, cognitive,
behavioral, and emotional impairment.9 Prior estimates … In order to characterize estimates of prevalence, and
prevalence across time, we calculated weighted
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
December 01, 2024 - This can
lead to inflated efficacy estimates and underestimated harms or burdens, as unpublished studies … Incorporating
FDA reviews could enhance the accuracy of effect estimates in systematic reviews. … Such omissions from systematic reviews may lead to
inflated estimates of drug efficacy because unpublished … We used point estimates and confidence
intervals to compare the effect sizes from the systematic review
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/masks-appendix-table-b-3-version-1.xlsx
February 01, 2020 - to 30.38)
Not reported Potential recall bias; no control for confounders; few cases and imprecise estimates