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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-4.pdf
    July 01, 2019 - Learning objective Statistical heterogeneity • Statistical heterogeneity occurs when estimates across … According to the 2019 Cochrane handbook, I2 describes the percentage of the variability in effect estimates
  2. effectivehealthcare.ahrq.gov/products/horizon-scan/research-2015
    October 01, 2015 - Report of a Pilot Project: Rapid Cost Analyses of Selected Potential High-Impact Intervention Reports Research Report October 1, 2015 Download Main Document PDF 404.8 KB This report is available in PDF (405 kB) only. People using assistive technology may not be able to fully access information in this…
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/coronary-stents-outcomes_research.pdf
    January 01, 2010 - were based upon Kaplan-Meier estimates for treatment-specific censoring distributions; whereas adjusted … estimates were based upon weights that were functions of Kaplan-Meier censoring estimates and propensity … score estimates.17,18 Adjusted hazard ratios were calculated according to the inverse probability … These models served to validate the adjusted hazard ratio estimates from the IPW Cox regression model … Such misclassification and underreporting should be non- differential, however, and should bias our estimates
  4. effectivehealthcare.ahrq.gov/products/rheumatoid-arthritis-medicine-1/research
    March 30, 2009 - data and although the overall and age-stratified changes in patterns of medication use were similar, estimates … Given the body of evidence supporting the benefits of DMARD therapies, these estimates would suggest … In contrast to previous estimates of DMARD utilization that were based on prevalence of use at any time
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
    January 01, 2021 - meta-analysis is appropriate (i.e., more than 2 studies address the same PICOTS and provide point estimates … If a meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates from … comparison have high or unclear risk of bias or when sensitivity analyses show substantial difference in estimates … derived from high or unclear risk of bias studies versus estimates derived from studies at low risk
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth_executive.pdf
    September 01, 2012 - Meta-Analysis We conducted a Bayesian meta-analysis to provide aggregate estimates of the effectiveness … We calculated meta-analysis estimates by using RCTs grouped by progestogen formulation (17OHP, oral, … For neonatal mortality, aggregate estimates indicated no formulation was effective at reducing risk … However, all formulations were effective at reducing the risk of preterm birth (meta-estimates: OR17OHP … In general, studies have also been too small to provide valid estimates of factors that may modify
  7. effectivehealthcare.ahrq.gov/products/coronary-stents-outcomes/research
    February 10, 2010 - were based upon Kaplan-Meier estimates for treatment-specific censoring distributions; whereas adjusted … estimates were based upon weights that were functions of Kaplan-Meier censoring estimates and propensity … score estimates. 17,18 Adjusted hazard ratios were calculated according to the inverse probability … These models served to validate the adjusted hazard ratio estimates from the IPW Cox regression model … Such misclassification and underreporting should be non-differential, however, and should bias our estimates
  8. effectivehealthcare.ahrq.gov/products/continuous-outcomes-quantitative-synthesis/methods
    July 25, 2013 - of continuous outcomes measured in RCTs: choice of effect measures of continuous outcomes, choice of estimates
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/progestogens-preterm-birth-disposition-121205.pdf
    September 07, 2012 - As above, we find the aggregate estimates of benefit among those with prior preterm birth to be squarely … We take some reassurance that providing summary evidence is sufficient since the meta-estimates for … Meta-estimates added to results section. … Point estimates and 95% confidence intervals are not consistently reported. … A summary table including all meta-estimates might be helpful.
  10. effectivehealthcare.ahrq.gov/sites/default/files/considerations-for-statistical-chapter-10.pptx
    January 01, 2013 - However, the DRS estimates the probability or rate of disease occurrence as a function of the covariates … If subjects with missing data differ from subjects with complete data, then exposure estimates may be
  11. effectivehealthcare.ahrq.gov/products/pressure-ulcer-treatment/research-protocol
    November 08, 2011 - Estimates of the incidence of pressure ulcers vary according to the setting and range from 0.4 to 38.0 … patients to full functioning. 2 Data on the costs of treatment for a pressure ulcer vary, but some estimates … Meta-analyses will be conducted to summarize data and obtain more precise estimates on outcomes for which … The Q statistic and/or the I 2 statistic (the proportion of variation in study estimates due to heterogeneity
  12. effectivehealthcare.ahrq.gov/sites/default/files/pdf/transparency-infertility_research.pdf
    June 01, 2017 - ............................... 7 v Background and Objectives Selective reporting can bias estimates … CT.gov for detecting selective reporting, and to determine the impact of selective reporting on the estimates … Therefore, our project coordinator sent regular queries to co-investigators asking for estimates of … These estimates were tracked in an Excel spreadsheet.
  13. S131 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/s131.pdf
    October 01, 2007 - of restrictions for use in pharmacoepidemiology and examines to what extent they change rate ratio estimates … RR estimates adjusted for age and sex also steadily increased. … For all earlier restrictions, it is less clear how much the observed change in RR estimates result from … We found that this change resulted in an observable but not substantial change in RR estimates in our … A, Unadjusted mortality rate ratio estimates; B, Multi- variate adjusted mortality rate ratio estimates
  14. effectivehealthcare.ahrq.gov/products/health-outcomes-competing-risks/abstract
    February 11, 2010 - Developing Methods to Assess Health Outcomes in the Presence of Competing Risks for Effectiveness Research Research Report February 11, 2010 Findings from this study were published in the following journal articles. 1. Weiss CO, Segal JB, Varadhan R. Assessing the applicability of trial evidence to a…
  15. effectivehealthcare.ahrq.gov/products/glycemic-control/abstract
    December 15, 2009 - Inverse-probability-of-treatment-weighted estimation for marginal structural models will be utilized to derive valid effect estimates
  16. effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
    November 20, 2013 - Empirical Bayes estimates generated in a hierarchical summary ROC analysis agreed closely with those … For diagnostic questions this means either ‘can the sensitivity and specificity estimates found in … or ‘do these sensitivity and specificity estimates tell me that the patient will benefit from this … What is the direction of sensitivity estimates, for example? … But sensitivity and specificity estimates lay between 0% and 100%.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
    November 08, 2011 - Estimates of the incidence of pressure ulcers vary according to the setting and range from 0.4 to 38.0 … patients to full functioning. 2 Data on the costs of treatment for a pressure ulcer vary, but some estimates … Meta-analyses will be conducted to summarize data and obtain more precise estimates on outcomes for … The Q statistic and/or the I 2 statistic (the proportion of variation in study estimates due to heterogeneity
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-chapter-3.pdf
    February 01, 2018 - Quantitative Synthesis Chapter 3. Choice of Statistical Model for Combining Studies Quantitative Synthesis Chapter 3. Choice of Statistical Model for Combining Studies Prepared for: The Agency for Healthcare Research and Quality (AHRQ) Training Modules for Systematic Reviews Methods Guide www.ahrq.gov Presenter…
  19. effectivehealthcare.ahrq.gov/products/dementia-agitation-aggression/research
    March 21, 2016 - We analyzed pooled estimates to assess efficacy and comparative effectiveness.
  20. TND-485-09-03-2013 (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/TND-485-09-03-2013.pdf
    January 01, 2013 - advance care plan Key Questions from Nominator: Will a decision aid, using individualized estimates

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