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effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - quantity of evidence, directness (or indirectness) of evidence, consistency of evidence, and precision of estimates … Includes considerations of:
Statistical significance for effect estimates
Confidence intervals for those … effect estimates
Four Required Domains: Precision
Four Required Domains: Precision
Precision is the … These estimates were consistent, direct, and precise. … Had these estimates been precise and consistent (i.e., a narrower CI for the RCT, consistent cohort studies
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effectivehealthcare.ahrq.gov/get-involved/nominated-topics/for-adult-patients-with-bipolar-disorder-including-bipolar-i-and-bipolar-ii-disorder-what-is-the-comparative-effectiveness-of-available-treatments-including-psychotherapy-other-psychosocial-treatments-medications-and-other-so
April 22, 2013 - and about 1% meet diagnostic criteria for bipolar II disorder (Merikangas et al. 2007), with other estimates … from community samples yielding estimates of up to approximately 4% for both bipolar I and II (Kessler … These estimates of prevalence are considered conservative, because of differences in diagnostic definitions
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effectivehealthcare.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - quantity of evidence, directness (or indirectness) of evidence, consistency of evidence, and precision of estimates … Includes considerations of:
Statistical significance for effect estimates
Confidence intervals for those … effect estimates
Four Required Domains: Precision
Precision is the degree of certainty surrounding … These estimates were consistent, direct, and precise. … Had these estimates been precise and consistent (i.e., a narrower CI for the RCT, consistent cohort studies
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effectivehealthcare.ahrq.gov/sites/default/files/sensitivity-analysis-chapter-11.pptx
January 01, 2013 - differences in the time window during which exposure is determined can lead to changes in study effect estimates … adjustment, may provide insight into which covariates have relatively greater influences on effect estimates … analysis is based on different assumptions than conventional approaches and may build confidence in estimates … For example, Samy Suissa (2008) illustrated how the choice of cohort definition can affect effect estimates … also consider the method of covariate adjustment to see if it might result in changes in the effect estimates
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
May 01, 2008 - is estimated that as many as 75% of all persons with
dementia will eventually reside in the NH. 7
Estimates … The aim of this project was to provide nationally representative estimates of the prevalence
of the … The
MCBS survey weights are used to project national estimates for each measure. … Data from claims provided slightly higher estimates of dementia cases
than self/proxy reports in the … Alzheimer disease in the US population:
Prevalence estimates using the 2000 census.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - Relative risk estimates were
derived from the meta-analyses and other age-specific and
race-specific … Depending on the
analysis, each model run included 5,000 to 1,000,000
simulated individuals; estimates … Decision Analysis: Benefits and
Harms of OC Use and Ovarian Cancer Risk
Using the point estimates from … of their effect on
mortality derived from a model are even more uncertain
than estimates for incident … Because
these data are cross-sectional, estimates for older women
reflect cohorts that were relatively
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - meta-analysis is appropriate (i.e., more than 2 studies address
the same PICOTS and provide point estimates … If
meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates
from … comparison have
high or unclear risk of bias or when sensitivity analyses show a substantial difference in
estimates … derived from high or unclear risk of bias studies versus estimates derived from
studies at low risk … Cardiovascular Disease Projections in the United
States Based on the 2020 Census Estimates.
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - The model will allow greater flexibility in exploring the potential effects of
these issues on estimates … For each outcome, we will use currently available estimates of lifetime
risk, prevalence of OC use, … and relative risk (or relative risk reduction) for that
outcome in OC users to generate estimates of … and cervical cancer, MI, stroke)
• Death from these other conditions
We will summarize these estimates … that provide any relevant data for model parameterization can be used to
provide initial parameter estimates
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
September 01, 2014 - ranging from 85 percent to 93 percent and specificity
estimates ranging from 94 percent to 100 percent … )
• For diagnosis using MRI, three systematic reviews
yielded sensitivity estimates of 84 percent to … 86 percent
and specificity estimates of 82 percent to 91 percent.20-22
(Strength of evidence from … )
• For diagnosis using PET/CT, three systematic reviews
yielded sensitivity estimates of 87 percent … to 90
percent and specificity estimates of 80 percent to 85
percent.20,23,24 (Strength of evidence
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effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - They look for consistency in direction of effect estimates in relation to the line that
distinguishes … For example, if all studies except one show estimates of effect in
the same direction, but the CI for … that one study overlaps the CIs for the estimates of effect in the
other studies, then this body of … Precision of outcome data estimates is
incompletely or not reported. … SMD estimates ranged from 0.13 to
0.94.
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effectivehealthcare.ahrq.gov/products/methods-binary-outcomes-evaluation/research
March 20, 2013 - In an accompanying simulation study, we compared summary estimates and their standard errors with univariate
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - We calculated meta-estimates of the
probability of leiomyosarcoma for all relevant studies and
by study … Lack of
precision means these estimates are not credibly different. … Some recent estimates in
the literature find otherwise. … Uncertainty in estimates of prevalence and evolving data
about methods for tissue extraction and their … Our
estimates and that of Pritts and colleagues10 find that
the estimates are lower in data from more
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effectivehealthcare.ahrq.gov/sites/default/files/exposure-definition-and-measurement_chapter-4.pptx
January 01, 2013 - appropriate for defining exposure
Provide evidence of validity of the operational definition of exposure with estimates … Evidence of validity may be provided by estimates of sensitivity, specificity, or positive predictive … This measurement error can result in biased estimates either away from or towards the null, making the … Evidence of validity may be provided by estimates of sensitivity, specificity, or positive predictive … Evidence of validity may be provided by estimates of sensitivity, specificity, or positive predictive
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effectivehealthcare.ahrq.gov/products/diabetes-foot-ulcer-amputation-prevalence/research
February 17, 2011 - These estimates are based on self-reports and are thought to underestimate the true prevalence by one-third … As expected, this is about one-third higher than previous CDC prevalence estimates.
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effectivehealthcare.ahrq.gov/products/medicare-eligible-disabled/research
June 15, 2012 - lived in institutional settings, and a 2003 estimate suggested a similar rate of 9.4 percent.9 These estimates … Most estimates suggest that disability rates among working-aged adults are rising.
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effectivehealthcare.ahrq.gov/sites/default/files/ch_2-user-guide-to-ocer_130129.pdf
January 01, 2011 - Confounding leads to biased treatment
effect estimates unless controlled for
by design (randomization … Nondifferential
measurement error in exposures and
outcomes tends to bias treatment effect
estimates … To do
so, the design uses controls as in a case-control
design but estimates a case-crossover odds … Description
As with the case-crossover design, the self-
controlled case-series design estimates the … Evidence of bias in estimates of influenza vaccine
effectiveness in seniors.
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effectivehealthcare.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
June 01, 2021 - quality of life, functional status, and cognitive function were often too limited to
determine effect estimates … neurocognitive decline and two favored the SRS alone group
compared to SRS plus WBRT but summary effect estimates … memantine and
hippocampal avoidance WBRT have only been reported in individual studies and
summary estimates
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effectivehealthcare.ahrq.gov/products/hepatitis-c-treatment-adherence/research-protocol
November 08, 2011 - The Centers for Disease Control and Prevention (CDC) estimates that 18,000 Americans were newly infected … We will document what methods the authors used to deal with loss to followup and the resulting estimates … , including effect measures, point estimates, 95 percent confidence intervals (95% CIs), and p -values … We will document the results reported by the authors, including effect measures, point estimates, 95% … On the basis of study characteristics, study quality, precision of estimates, and magnitude of effects
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effectivehealthcare.ahrq.gov/products/transparency-infertility/research-protocol
September 03, 2016 - 3, 2016 Download Main Document PDF 316.7 KB
Background
Selective reporting can bias estimates … Goals
The overall goal of this project is to determine whether selective reporting introduces biased estimates … Therefore, our project coordinator will send weekly queries to co-investigators asking for estimates … These estimates will be tracked in an excel spreadsheet.
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/primary-healthcare-spending-draft-tech-brief-appendixes.pdf
August 08, 2023 - What are the implications of different definitions of primary care on estimates of primary
care spending … -2011-
Framework.pdf
Google OECD report on primary care
spending estimates among
participating … Spending on Primary
Care: First Estimates. Dec 2018. … Deriving Preliminary
Estimates of Primary Care Spending under
the SHA 2011 Framework. 2019. … https://www.oecd.org/health/health-
systems/Preliminary-Estimates-of-Primary-
Care-Spending-under-SHA