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Showing results for "estimates".

241. Behavioral Programs for Type 1 Diabetes Mellitus: Current State of the Evidence (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/diabetes-behavior-programs_clinician-2016.pdf
     January 01, 2016 - Behavioral Programs for Type 1 Diabetes Mellitus: Current State of the Evidence Behavioral Programs for Type 1 Diabetes Mellitus: Current State of the Evidence Focus of This Summary This is a summary of a systematic review evaluating the evidence about the effectiveness of behavioral programs for type 1 diabete…

242. Core-Needle Biopsy for Breast Abnormalities (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_clinician.pdf
     May 01, 2016 - Core-Needle Biopsy for Breast Abnormalities Core-Needle Biopsy for Breast Abnormalities Clinical Issue About one in eight women in the United States will develop invasive breast cancer during her lifetime. Approximately 290,000 new cases of breast cancer are diagnosed each year in the United States, and more than…

243. Heart-Failure-Transition-Care Clinician (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_clinician.pdf
     October 01, 2015 - Transitional Care Interventions To Prevent Readmissions for People With Heart Failure Focus of This Summary This is a summary of a systematic review evaluating the evidence regarding the efficacy, comparative effectiveness, and harms of transitional care interventions (defined in Table 1) that aim to reduce readmiss…

244. Physiologic Predictors of the Need for Trauma Center Care: A Systematic Review | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/predictors-trauma-care/research-protocol
     December 01, 2019 - We include three different approaches to assessing predictive utility: (1) adjusted risk estimates (e.g … Adjusted risk estimates may include odds ratios, risk ratios, and hazard ratios. … We will report point estimates and confidence intervals or significance and record reported values and … We include three different approaches to assessing predictive utility: (1) adjusted risk estimates (e.g … We include three different approaches to assessing predictive utility: (1) adjusted risk estimates (e.g

245. Transitional Care Interventions To Prevent Readmissions for People With Heart Failure (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/heart-failure-transition-care_policymaker.pdf
     August 01, 2016 - Transitional Care Interventions To Prevent Readmissions for People With Heart Failure B A C K G R O U N D Heart failure (HF) is a major clinical and public health problem and a leading cause of hospitalization and health care costs in the United States. Despite a decline in HF-related hospitalizations during the …

246. Diagnosis and Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/chronic-fatigue/research-protocol
     December 01, 2019 - Meta-analyses will be conducted to summarize data and obtain more precise estimates on outcomes for which

247. Heart-Failure-Natriuretic-Peptide Executive (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
     November 01, 2013 - 5.7 million Americans, and 670,000 new cases are diagnosed annually.1 Based on current population estimates … For detecting advanced DD, AUC estimates were 0.89 (cutpoint, 70 pg/mL; sensitivity, 83%; specificity … It was determined that at least four studies were needed in each group to present summary estimates; … Consistency In terms of BNP sensitivity, the directions of the estimates are consistent, and with the … However, we rate the specificity as inconsistent because the range of estimates across studies for

248. Diabetes Medications for Adults with Type 2 Diabetes: An Update Focused on Monotherapy and Add-on Therapy to Metformin | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/diabetes-update-2015/research-protocol
     December 01, 2019 - If we see substantial heterogeneity (I-squared >50%) in pooled estimates for any outcome, we will explore … heterogeneity among studies with an I-squared statistic, which describes the variability in effect estimates … analyses by omitting one study at a time to assess the influence of any single study on the pooled estimates … National Diabetes Statistics Report: Estimates of Diabetes and Its Burden in the United States, 2014. … National Diabetes Fact Sheet: National Estimates and General Information on Diabetes and Prediabetes

249. Supplemental Evidence and Data Guidelines | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/get-involved/submit-sead/guidelines
     November 01, 2022 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

250. Assessing-The-Risk-Of-Bias-In-Systematic-Reviews-Of-Health-Care-Interventions (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01_0.pdf
     May 01, 2005 - or outcome assessors (particularly for subjective outcomes) are not blinded.4, 6 The influence on estimates … Despite the likely lack of empirical evidence for quantitatively adjusting estimates to account for … Conversely, a review with a poor search strategy may lead to estimates that do not represent the totality … Influence of reported study design characteristics on intervention effect estimates from randomized … Systematic evaluation of the impact of analytical choices on effect estimates in observational studies

251. Comparative Effectiveness of Adjunctive Devices to Remove Thrombi or Protect Against Distal Embolization in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention of Native Vessels | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/acs-pci-adjunctive-devices/research-protocol
     December 01, 2019 - Skip to main content An official website of the Department of Health & Human Services Careers Contact Us Español FAQs Effective Health Care Program Powered by the Evidence-based Practice Centers …

252. Comparative Effectiveness of Treatments for Cryptorchidism | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/undescended-testicle/research-protocol
     December 01, 2019 - respectively, cryptorchidism incurs direct costs of millions of dollars annually, even by the most modest estimates

253. Integrating Bodies of Evidence: Existing Systematic Reviews and Primary Studies | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/integrating-evidence/methods
     December 01, 2019 - precision, directness and reporting bias), review authors should consider how new evidence would change estimates … approaches for combining new studies with the summary estimate from prior meta-analyses versus with estimates … As new methods are developed or old methods questioned, when are the prior estimates no longer considered … For instance, if the prior review used DerSimonian-Laird model, 19 do new summary estimates need to … models for meta-analysis were used, are there standards that can be established for when the prior estimates

254. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
     June 01, 2012 - a meta-analysis to summarize test performance depending on whether the sensitivity and specificity estimates … There are two goals for a meta-analysis in a systematic review: Provide summary estimates for key quantities … Use the summary line when there are different thresholds for positive tests or estimates vary widely. … These estimates were calculated using bivariate meta-regression with time interval as the predictor. … Sensitivity and specificity estimates of various studies do not vary widely.

255. Meta-analysis of Test Performance Evidence When There is a “Gold Standard” Reference Standard (ppt file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
     June 01, 2012 - a meta-analysis to summarize test performance depending on whether the sensitivity and specificity estimates … There are two goals for a meta-analysis in a systematic review: Provide summary estimates for key quantities … Use the summary line when there are different thresholds for positive tests or estimates vary widely. … These estimates were calculated using bivariate meta-regression with time interval as the predictor. … Sensitivity and specificity estimates of various studies do not vary widely.

256. Assessing-The-Risk-Of-Bias-In-Systematic-Reviews-Of-Health-Care-Interventions (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/assessing-the-risk-of-bias-in-systematic-reviews-of-health-care-interventions-01.pdf
     May 01, 2005 - or outcome assessors (particularly for subjective outcomes) are not blinded.4, 6 The influence on estimates … Despite the likely lack of empirical evidence for quantitatively adjusting estimates to account for … Conversely, a review with a poor search strategy may lead to estimates that do not represent the totality … Influence of reported study design characteristics on intervention effect estimates from randomized … Systematic evaluation of the impact of analytical choices on effect estimates in observational studies

257. Comparative Effectiveness of Pharmacologic Therapies for the Management of Crohn’s Disease | Effective Health Care (EHC) Program
     effectivehealthcare-admin.ahrq.gov/products/crohns-disease/research-protocol
     December 01, 2019 - identifying all paths that contribute to the indirect comparisons and calculation of their effects estimates … This analysis will also generate the point estimates and measure of heterogeneity for each direct comparison … To assess inconsistency, we will provide direct and indirect estimates for each comparison and compare … determine whether there is important inconsistency we will test differences between direct and indirect estimates

258. White Paper: Enhancing Systematic Review Methods by Incorporating Unpublished Drug Trials (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/unpublished-drug-trials-white-paper.pdf
     December 01, 2024 - This can lead to inflated efficacy estimates and underestimated harms or burdens, as unpublished studies … Incorporating FDA reviews could enhance the accuracy of effect estimates in systematic reviews. … Such omissions from systematic reviews may lead to inflated estimates of drug efficacy because unpublished … We used point estimates and confidence intervals to compare the effect sizes from the systematic review

259. Evidence-based Practice Center Systematic Review Protocol: Prehospital Airway Management (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/prehospital-airway-management-protocol.pdf
     December 20, 2019 - Meta-analyses will be conducted if possible to combine data and obtain more precise estimates on outcomes … for which studies are homogeneous enough to provide meaningful pooled estimates.6 The decision to conduct

260. chronic-fatigue-protocol (pdf file)
     effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
     May 01, 2014 - Meta-analyses will be conducted to summarize data and obtain more precise estimates on outcomes for