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effectivehealthcare-admin.ahrq.gov/sites/default/files/s96.pdf
October 01, 2007 - Thus, final analyses based on
MedDRA coding and computing national estimates may not be
performed until … Estimates from 2004 to 2005 indicate that more than
700,000 patients were treated annually in US emergency … sitivity and high PPV in NEISS-CADES suggests that the
true number of ADEs may be higher than national estimates … Finally, NEISS-CADES does
not provide estimates of drug exposure in the surveillance
population.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_disposition-comments.pdf
March 10, 2010 - We have included relative risk estimates for each
subgroup in the text when they are calculated. … We considered estimates precise if they provided
statistically significant differences between drugs … The next sentence goes on to say, "Estimates were also
considered precise if they showed no statistical … We assumed that women take the drug for 5 years and NNT
estimates were calculated for a 5-year period … of
number needed to treat have been added to provide absolute
estimates of risk that are more useful
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/rheumatoid-arthritis-medicine-1_research.pdf
February 01, 2009 - data and although the overall and age-stratified changes in patterns of
medication use were similar, estimates … Given the body of evidence supporting the
benefits of DMARD therapies, these estimates would suggest … In contrast to
previous estimates of DMARD utilization that were based on prevalence of use at any time
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/transparency-infertility_research-protocol.pdf
September 02, 2016 - Background
Selective reporting can bias estimates of effect, yet methods to detect such biases are … The overall goal of this project is to determine whether selective reporting introduces biased
estimates … Therefore, our project coordinator will send
weekly queries to co-investigators asking for estimates … These estimates will be tracked in an excel spreadsheet.
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effectivehealthcare-admin.ahrq.gov/products/anxiety-children/research-protocol
June 01, 2021 - The National Institute of Mental Health (NIMH) estimates a lifetime prevalence between the ages 13 and … whether meta-analysis is appropriate (i.e., more than 2 trials address the same PICOTS and provide point estimates … Conducting network meta-analysis requires satisfying three assumptions, homogeneity of the direct estimates … , consistency between direct and indirect estimates, and transitivity. … Depending on the geometry of networks [closed loop (with direct estimates available) vs. open (unconnected
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/preterm-birth-terbutaline-pump_research-protocol.pdf
October 18, 2010 - preterm labour (i.e. cervical length and cervical dilation), we will also explore whether
effect estimates … For rare outcomes,
only studies with events recorded will be included in combined estimates. … studies.11 While analyses that do not account for
clustering effects do not lead to biased effect estimates … with singletons and,
therefore, any overweighting that arises by including these studies in pooled estimates … October 18, 2010
19
Sensitivity analyses are planned to explore the robustness of combined
estimates
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effectivehealthcare-admin.ahrq.gov/products/back-pain-treatment/research-protocol
December 01, 2019 - Meta-analyses will be conducted to summarize data and obtain more precise estimates on outcomes for which … the pooled estimate, and the likelihood that results from new studies would impact conclusions and estimates … Estimates and patterns of direct health care expenditures among individuals with back pain in the United
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/pressure-ulcer-prevention_disposition-comments.pdf
May 08, 2013 - Unfortunately it is difficult to
obtain an accurate estimates of pressure ulcer incidence in
the U.S … The
ranges for these estimates are extremely wide varying by
several orders of magnitude in some cases … However, we
added this sentence regarding the variability in rates: The
variation in estimates is due … We replaced references to review articles for estimates of
cost. … Some estimates come from guidelines, position
statements, or key review articles and we believe are
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effectivehealthcare-admin.ahrq.gov/sites/default/files/product/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - There sometimes is heterogeneity in estimates of treatment effect between RCTs and NRSIs. … Moreover, because of their generally large
sample sizes, effect size estimates from individual NRSIs … and
confidence intervals, and if they are generally consistent with RCT effect estimates and
confidence … and confidence intervals, in most instances, reviewers should avoid meta-analyzing
estimates across … Effect
Estimates in Randomized Trials and
Observational Studies: Comparing Apples
With Apples.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/wysiwyg/pdf/methods-guide-inclusion-nonrandomized-studies.pdf
September 01, 2022 - There sometimes is heterogeneity in estimates of treatment effect between RCTs and NRSIs. … Moreover, because of their generally large
sample sizes, effect size estimates from individual NRSIs … and
confidence intervals, and if they are generally consistent with RCT effect estimates and
confidence … and confidence intervals, in most instances, reviewers should avoid meta-analyzing
estimates across … Effect
Estimates in Randomized Trials and
Observational Studies: Comparing Apples
With Apples.
-
effectivehealthcare-admin.ahrq.gov/products/breast-abnormalities-tests-update/research-protocol
December 01, 2019 - Breast cancer is the second most common malignancy of women. 2 The American Cancer Society estimates … typically were of lower methodological quality and that excluding them had little effect on effect size estimates … ultrasound without a contrast agent to the accuracy of ultrasound with a contrast agent, if the sensitivity estimates … Precision may be rated separately for summary estimates of sensitivity and specificity for each major … tests, the conclusion will be rated as being “precise” if the confidence intervals around the summary estimates
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/head-neck-cancer-update_clinician.pdf
August 01, 2015 - Radiotherapy Treatments for Head and Neck Cancer
Radiotherapy Treatments for Head and Neck Cancer
Background
Clinical Bottom Line
and stereotactic body RT (SBRT). Charged particle-based
conformal external-beam RT modalities, such as proton-beam
RT (PBT), are also available to treat head and neck cancer,
althou…
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/hepatitis-c-screening_executive.pdf
November 01, 2012 - vertical) transmission is believed to be
the main route of HCV infection acquisition in children.44
Estimates … a few studies and the summary
range highlighted the greater variability (and uncertainty)
in the estimates … the
estimate of effect, based on the number and size of studies
and confidence intervals for the estimates … Estimates of serious
harms associated with liver biopsy are also consistent
with estimates from the … The applicability of estimates of serious
harms such as bleeding from such studies to a screen-
detected
-
effectivehealthcare-admin.ahrq.gov/products/dietary-supplements/research-protocol
December 01, 2019 - The Magnitude of the Problem: The American Heart Association estimates that more than 81 million American … Dietary supplements have become popular for treatment and prevention of illness, with estimates suggesting … Do the effect estimates of clinical cardiovascular outcomes vary by age, ethnicity, gender, or health … Do the effect estimates of harms outcomes vary by age, ethnicity, gender, or health status? … Do the effect estimates of pharmacokinetic outcomes vary by age, ethnicity, gender, or health status?
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_clinician.pdf
July 01, 2016 - Management of Postpartum Hemorrhage: Current State of the Evidence
Management of Postpartum Hemorrhage:
Current State of the Evidence
Focus of This Summary
This is a summary of a systematic review evaluating the evidence regarding the potential benefits and harms of medical and/or
surgical strategies used to man…
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effectivehealthcare-admin.ahrq.gov/sites/default/files/masks-appendix-table-b-3-version-2.xlsx
February 01, 2020 - to 30.38)
Not reported Potential recall bias; no control for confounders; few cases and imprecise estimates … 0.03 to 6.18) Not reported Not reported Potential recall bias; no control for confounding; imprecise estimates
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/Masks-appendix-table-b-3-surveillance-report.xlsx
February 01, 2020 - to 30.38)
Not reported Potential recall bias; no control for confounders; few cases and imprecise estimates … 0.03 to 6.18) Not reported Not reported Potential recall bias; no control for confounding; imprecise estimates
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/masks-surveillance-2-appendix-table-a-3.xlsx
March 23, 2020 - to 30.38)
Not reported Potential recall bias; no control for confounders; few cases and imprecise estimates … 0.03 to 6.18) Not reported Not reported Potential recall bias; no control for confounding; imprecise estimates
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - Sample Size Estimates for Various Clinical Scenarios of Sensitivity and Specificity
With an Assumed … Benefit and cost estimates can have both internal and external
validity. … These estimates should include clinical, work-related, accident, and quality of
life outcomes. … Out-of-pocket patient costs should also be included in cost estimates. … Adjustment should be made for major outcomes and
adverse events, using rate and utility estimates.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pressure-ulcer-prevention_research-protocol.pdf
January 10, 2012 - adults in the United
States, with notable variation in incidence rates by medical care setting.
1
Estimates … 2008 and 12.3 percent in 2009.
5
Data on the cost of treatment for a pressure ulcer vary, but some estimates … Meta-analyses will be conducted to summarize data and obtain more precise estimates on
outcomes for