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effectivehealthcare-admin.ahrq.gov/sites/default/files/s23.pdf
October 01, 2007 - examples of communicating benefits and harms
for well-known therapeutics, illustrating that relative risk estimates … Although the estimates might change when more information
from other studies becomes available, the public … For the most part, the articles discuss
relative estimates (relative risks or odds ratios; Fig. 1). … Relative risk estimates are not helpful for communicating
the chance of experiencing an event (either … benefit or a
harm).9,29 In our scenario, relative risk estimates cannot
accurately depict the chance
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
April 01, 2014 - Results from these studies
therefore could not be included in summary estimates for sensitivity and … specificity, resulting in
less robust and potentially biased estimates. … is obtained and how that
information affects the conclusions of the systematic review, including estimates … The additional data
enabled somewhat more robust estimates for diagnostic accuracy at commonly used … Although the effects on summary estimates were relatively small in most
cases, the changes had important
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/primary-healthcare-spending-disposition-comments.pdf
May 17, 2024 - but only mention
one (PCC) and focus primarily on state estimates. … We have clarified
the number of
reports and
estimates we
found throughout
the report. … KI Reviewer 1 General
Comments
In the abstract it says you found 3 national estimates but
elsewhere … We will
revise the text to
clarify what
estimates we are
referring to. … I believe MA also
may include this method for its non-claims estimates.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/grading.ppt
January 01, 2010 - quantity of evidence, directness (or indirectness) of evidence, consistency of evidence, and precision of estimates … Includes considerations of:
Statistical significance for effect estimates
Confidence intervals for those … effect estimates
Four Required Domains: Precision
Four Required Domains: Precision
Precision is the … These estimates were consistent, direct, and precise. … Had these estimates been precise and consistent (i.e., a narrower CI for the RCT, consistent cohort studies
-
effectivehealthcare-admin.ahrq.gov/products/hepatitis-c-treatment-adherence/research-protocol
December 01, 2019 - The Centers for Disease Control and Prevention (CDC) estimates that 18,000 Americans were newly infected … We will document what methods the authors used to deal with loss to followup and the resulting estimates … , including effect measures, point estimates, 95 percent confidence intervals (95% CIs), and p -values … We will document the results reported by the authors, including effect measures, point estimates, 95% … On the basis of study characteristics, study quality, precision of estimates, and magnitude of effects
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/grading.ppt
January 01, 2013 - quantity of evidence, directness (or indirectness) of evidence, consistency of evidence, and precision of estimates … Includes considerations of:
Statistical significance for effect estimates
Confidence intervals for those … effect estimates
Four Required Domains: Precision
Precision is the degree of certainty surrounding … These estimates were consistent, direct, and precise. … Had these estimates been precise and consistent (i.e., a narrower CI for the RCT, consistent cohort studies
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
May 01, 2008 - is estimated that as many as 75% of all persons with
dementia will eventually reside in the NH. 7
Estimates … The aim of this project was to provide nationally representative estimates of the prevalence
of the … The
MCBS survey weights are used to project national estimates for each measure. … Data from claims provided slightly higher estimates of dementia cases
than self/proxy reports in the … Alzheimer disease in the US population:
Prevalence estimates using the 2000 census.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-ovarian-contraceptives_executive.pdf
June 01, 2013 - Relative risk estimates were
derived from the meta-analyses and other age-specific and
race-specific … Depending on the
analysis, each model run included 5,000 to 1,000,000
simulated individuals; estimates … Decision Analysis: Benefits and
Harms of OC Use and Ovarian Cancer Risk
Using the point estimates from … of their effect on
mortality derived from a model are even more uncertain
than estimates for incident … Because
these data are cross-sectional, estimates for older women
reflect cohorts that were relatively
-
effectivehealthcare-admin.ahrq.gov/products/predictors-trauma-care/research-2018
December 01, 2019 - We used data provided to calculate values that were not reported and pooled estimates across studies … sensitivities ranging from 13% to 74% and specificities ranging from 62% to 96% for out-of-hospital pooled estimates
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - meta-analysis is appropriate (i.e., more than 2 studies address
the same PICOTS and provide point estimates … If
meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates
from … comparison have
high or unclear risk of bias or when sensitivity analyses show a substantial difference in
estimates … derived from high or unclear risk of bias studies versus estimates derived from
studies at low risk … Cardiovascular Disease Projections in the United
States Based on the 2020 Census Estimates.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/cancer-ovarian-contraceptives_research-protocol.pdf
March 13, 2012 - The model will allow greater flexibility in exploring the potential effects of
these issues on estimates … For each outcome, we will use currently available estimates of lifetime
risk, prevalence of OC use, … and relative risk (or relative risk reduction) for that
outcome in OC users to generate estimates of … and cervical cancer, MI, stroke)
• Death from these other conditions
We will summarize these estimates … that provide any relevant data for model parameterization can be used to
provide initial parameter estimates
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/cancer-pancreas_executive.pdf
September 01, 2014 - ranging from 85 percent to 93 percent and specificity
estimates ranging from 94 percent to 100 percent … )
• For diagnosis using MRI, three systematic reviews
yielded sensitivity estimates of 84 percent to … 86 percent
and specificity estimates of 82 percent to 91 percent.20-22
(Strength of evidence from … )
• For diagnosis using PET/CT, three systematic reviews
yielded sensitivity estimates of 87 percent … to 90
percent and specificity estimates of 80 percent to 85
percent.20,23,24 (Strength of evidence
-
effectivehealthcare-admin.ahrq.gov/products/coronary-stents-outcomes/research
January 01, 2020 - were based upon Kaplan-Meier estimates for treatment-specific censoring distributions; whereas adjusted … estimates were based upon weights that were functions of Kaplan-Meier censoring estimates and propensity … score estimates. 17,18 Adjusted hazard ratios were calculated according to the inverse probability … These models served to validate the adjusted hazard ratio estimates from the IPW Cox regression model … Such misclassification and underreporting should be non-differential, however, and should bias our estimates
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - They look for consistency in direction of effect estimates in relation to the line that
distinguishes … For example, if all studies except one show estimates of effect in
the same direction, but the CI for … that one study overlaps the CIs for the estimates of effect in the
other studies, then this body of … Precision of outcome data estimates is
incompletely or not reported. … SMD estimates ranged from 0.13 to
0.94.
-
effectivehealthcare-admin.ahrq.gov/products/immunity-after-covid/rapid-review
April 01, 2023 - Analysis of larger, more diverse cohorts of previously infected individuals could help verify whether the estimates … Nevertheless, the protection estimates for asymptomatic and symptomatic infection were similar, and the
-
effectivehealthcare-admin.ahrq.gov/products/risk-cardiovascular-disease/protocol
December 01, 2023 - a meta-analysis is appropriate (i.e., more than 2 studies address the same PICOTS and provide point estimates … If meta-analysis is deemed appropriate, we plan to use random-effects models to pool estimates from the … comparison have high or unclear risk of bias or when sensitivity analyses show a substantial difference in estimates … derived from high or unclear risk of bias studies versus estimates derived from studies at low risk … Cardiovascular Disease Projections in the United States Based on the 2020 Census Estimates.
-
effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/evidence-summary-cer-195-uterine-fibroids-final.pdf
December 01, 2017 - We calculated meta-estimates of the
probability of leiomyosarcoma for all relevant studies and
by study … Lack of
precision means these estimates are not credibly different. … Some recent estimates in
the literature find otherwise. … Uncertainty in estimates of prevalence and evolving data
about methods for tissue extraction and their … Our
estimates and that of Pritts and colleagues10 find that
the estimates are lower in data from more
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effectivehealthcare-admin.ahrq.gov/products/transparency-infertility/research-protocol
January 01, 2019 - Page Contents
Background
Selective reporting can bias estimates … Goals
The overall goal of this project is to determine whether selective reporting introduces biased estimates … Therefore, our project coordinator will send weekly queries to co-investigators asking for estimates … These estimates will be tracked in an excel spreadsheet.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/cer-242-radiation-therapy-brain-metastases-evidence-summary.pdf
June 01, 2021 - quality of life, functional status, and cognitive function were often too limited to
determine effect estimates … neurocognitive decline and two favored the SRS alone group
compared to SRS plus WBRT but summary effect estimates … memantine and
hippocampal avoidance WBRT have only been reported in individual studies and
summary estimates
-
effectivehealthcare-admin.ahrq.gov/products/diabetes-foot-ulcer-amputation-prevalence/research
December 01, 2019 - These estimates are based on self-reports and are thought to underestimate the true prevalence by one-third … As expected, this is about one-third higher than previous CDC prevalence estimates.