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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/ehc-presentation-quantitative-synthesis-learning-objectives-recommendations.pdf
July 01, 2019 - Quantitative Synthesis: Learning Objectives and Recommendations
Quantitative Synthesis
Learning Objectives and Recommendations
Background
• Purpose:
► To consolidate and update guidance from prior methods guides
► Focuses on Comparative Effectiveness Reviews (CERs):
− Systematic reviews comparing effectiveness …
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effectivehealthcare-admin.ahrq.gov/products/crohns-disease/research-protocol
December 01, 2019 - The absolute effect (or efficacy) for each treatment will be estimated by adding the treatment specific
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/pelvic-pain_research-protocol.pdf
February 16, 2011 - Given the lack of established definitions for CPP, prevalence has been variously estimated. … noncyclic pelvic pain (i.e., not occurring in concert with menstruation or in a
temporal pattern) was estimated … rate in the United States at
14.7%.8 Annual costs of outpatient visits in the United States have been estimated … reports and the nonoriginal research studies were eliminated, more than 1,600
studies remained with an estimated
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/osteoarthritis-pain_executive.pdf
October 01, 2011 - One study
estimated the number at 3,200 annually in the 1990s11,
though other studies have reported higher
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effectivehealthcare-admin.ahrq.gov/products/antipsychotics/research-protocol
January 01, 2019 - . 3 , 4 Delirium is strongly associated with increased mortality and longer hospital stay, with an estimated
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
October 01, 2015 - 10th most
commonly diagnosed cancer in women in
the United States.1 The American Cancer
Society estimated … Table B shows estimated
probabilities for bladder cancer following use of urinary
biomarkers, based
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_research-protocol.pdf
January 27, 2012 - numerous health and social problems, more than 85,000 deaths per year in the United
States,4-5 and an estimated … annual cost to society of more than $220 billion.6,7 Alcohol
misuse is estimated to be the third leading … dependence represents one of the most undertreated disorders in the U.S. health care
system; it is estimated … potential to improve health outcomes and reduce the burden of this devastating illness
that affects an estimated
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/hemorrhage-postpartum_research-protocol.pdf
June 11, 2014 - The overall prevalence of PPH worldwide is estimated to be 6 to 11 percent.5, 6 Rates
vary by data source … appraisal of blood loss and 7.2 percent when
assessed with subjective techniques.5 A systematic review estimated … Visually estimated and calculated blood loss in
vaginal and cesarean delivery.
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/stent-clopidogrel-practice_research.pdf
March 01, 2009 - Inverse probability weighted adjusted estimates were based on
estimated propensity scores and Cox proportional … constructed using inverse probability weights.
18
Four treatment-drug group propensity scores were estimated
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/arthritis-knee-physical-therapy_research-protocol.pdf
April 01, 2010 - global score or ranking category of overall quality.31,38
Applicability of the population will be estimated … Applicability of the population will be estimated by evaluating subject
selection in observational studies
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effectivehealthcare-admin.ahrq.gov/products/atypical-antipsychotics-off-label-update/research-protocol
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effectivehealthcare-admin.ahrq.gov/products/methods-balancing-harms-benefits/research-2012
November 01, 2017 - of a review, relative to a qualitative approach, by being explicit about how benefits and harms are estimated
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effectivehealthcare-admin.ahrq.gov/products/bladder-cancer-muscle-invasive/research-protocol
December 01, 2020 - Assessing Applicability
Applicability will be estimated by examining the characteristics of the patient
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effectivehealthcare-admin.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_executive.pdf
November 01, 2013 - The estimated
total cost for HF in 2010 was $39.2
billion, or 1 to 2 percent of all health care
expenditures … created for each
study where true positive, false positive, false negative,
and true negative could be estimated … positive likelihood, negative likelihood,
and diagnostic odds ratios are derived as functions of the
estimated … two groups, namely those
with or without HF.41
Renal function: Four42,48,51,67 articles examined estimated
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
October 01, 2016 - randomized trials
cannot be used to inform all model parameters because (1) some parameters are best estimated … from other study designs (e.g., the prevalence of a risk factor is best estimated from a sampling … survey of a representative population; the performance of a diagnostic test is best estimated from
a
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/delirium-research-protocol.pdf
June 01, 2018 - years.3, 4 Delirium is strongly associated with increased mortality and longer
hospital stay, with an estimated
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effectivehealthcare-admin.ahrq.gov/products/opioids-chronic-pain/protocol
May 01, 2020 - percent had high impact chronic pain. 2 Chronic pain is associated with an annual cost conservatively estimated … 165,000 people died from overdose related to prescription opioids in the United States, 8 with an estimated
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effectivehealthcare-admin.ahrq.gov/products/liver-cancer/research-protocol
December 01, 2019 - The age-adjusted death rate is estimated at 5.2 per 100,000 people per year in the United States, with … When the between-study heterogeneity is estimated to be zero, the random-effects model produces the same … Assessing Applicability
Applicability will be estimated by examining:
Characteristics of the patient
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effectivehealthcare-admin.ahrq.gov/sites/default/files/pdf/nonpharm-treatment-chronic-pain-protocol.pdf
December 11, 2018 - It affects
millions of adults in the United States, with a conservative annual cost estimated at $560
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effectivehealthcare-admin.ahrq.gov/products/noninvasive-nonpharm-pain-update/protocol
May 01, 2020 - It affects millions of adults in the United States, with a conservative annual cost estimated at $560