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  1. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/aspirin-use-prevent-cardiovascular-disease-colorectal-cancer-preventive-medication-2002
    January 15, 2002 - Neither trial had sufficient power to precisely estimate major harms such as gastrointestinal bleeding … This estimate is higher than that in Sudlow's meta-analysis, which included only primary prevention trials … Risk for future CHD events can be predicted from coronary risk algorithms. 29 Factors used to estimate … Augustovski et al. 31 used existing studies to estimate utility values as follows: nonfatal myocardial … They further estimated that the upper end of the 95 percent confidence interval for this point estimate
  2. www.uspreventiveservicestaskforce.org/home/getfilebytoken/xUc_vXf7323faUQY7SePhT
    January 01, 2002 - Neither trial had sufficient power to precisely estimate major harms such as gastrointestinal bleeding … Sudlow25 recently performed a similar analysis using all 5 trials and reached a similar effect estimate … Risk for future CHD events can be predicted from coronary risk algorithms.30 Factors used to estimate … Augustovski et al32 used existing studies to estimate utility values as follows: nonfatal myocardial … They further estimated that the upper end of the 95% confidence interval for this point estimate occurred
  3. www.uspreventiveservicestaskforce.org/home/getfilebytoken/4z_ByGyYfKV5uRU6fjx8pB
    March 01, 2014 - Nine studies provided data to estimate sensitivity and specificity of OGCT using a cut-point of 140 mg … Infant Outcomes The pooled estimate from 3 fair- and good-quality RCTs (n � 2044) showed a significant … A pooled estimate from 5 fair- and good-quality RCTs showed significantly lower incidence of macrosomia … Estimate of Magnitude of Net Benefit The USPSTF determined that screening for and treat- ment of GDM … The USPSTF was not able to estimate the magnitude of net benefit for screening for or treatment of GDM
  4. www.uspreventiveservicestaskforce.org/uspstf/recommendation/gestational-diabetes-mellitus-screening-january-2014
    January 14, 2014 - diagnostic tests for GDM before 24 weeks of gestation were limited. 1 Nine studies provided data to estimate … good-quality RCTs and 1 good-quality cohort study provided evidence on preeclampsia. 9-12 The pooled estimate … outcomes, such as type 2 diabetes mellitus, obesity, and hypertension. 1 Infant Outcomes The pooled estimate … There was no statistical heterogeneity across the studies. 1 A pooled estimate from 5 fair- and good-quality … The USPSTF was not able to estimate the magnitude of net benefit for screening for or treatment of GDM
  5. www.uspreventiveservicestaskforce.org/home/getfilebytoken/6dqHx6xQGq9GUv92rZUf2q
    August 01, 2022 - - Estimate CVD risk using a CVD risk estimator.
  6. www.uspreventiveservicestaskforce.org/home/getfilebytoken/rts4chTw2sVprMEF5xpMYS
    April 01, 2022 - • For adults aged 40 to 59 years: Estimate CVD risk using a CVD risk estimator.
  7. www.uspreventiveservicestaskforce.org/uspstf/document/modeling-study/lung-cancer-screening
    March 09, 2021 - available evidence and predict long-term outcomes, 13-15 the USPSTF commissioned a simulation analysis to estimate … models developed within the Cancer Intervention and Surveillance Modeling Network (CISNET) were used to estimate … Assessment Tool model, 23 and the Bach model 24 ) that use smoking duration and intensity, sex, and age to estimate … Scenario Simulation and Analysis The CISNET simulation models were used to estimate the benefits and … models (Massachusetts General Hospital–Harvard Medical School and University of Michigan) were used to estimate
  8. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary-harms-of-screening-for-breast-cancer/breast-cancer-screening-january-2016
    January 11, 2016 - Various methods were used to estimate overdiagnosis. … An estimate of overdiagnosis 15 years after the start of mammographic screening in Florence. … Estimate of overdiagnosis of breast cancer due to mammography after adjustment for lead time. … : observed vs. expected population cumulative incidence in 2005–2009 Participation estimate: 17.3% … Population estimate: 6.7% Participation estimate: 5.4% Population estimate: −0.7% NR
  9. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/asymptomatic-bacteriuria-in-adults-screening
    September 24, 2019 - Random-effects meta-analysis was conducted to estimate benefits of the interventions. … heterogeneity among the pooled studies was evaluated with standard χ2 tests and the I 2 statistic to estimate … group (placebo or no treatment) than in the treated group in all but 1 study. 29 The pooled effect estimate … small sample sizes, none of the studies reported statistically significant effects, and the pooled estimate … were observed in the control groups than in the intervention groups in all but 1 study. 19 The pooled estimate
  10. www.uspreventiveservicestaskforce.org/uspstf/document/other-supporting-document19468/tobacco-and-nicotine-use-prevention-in-children-and-adolescents-primary-care-interventions
    April 28, 2020 - usual care on the likelihood of adult smoking (odds ratio [OR], 0.78 [95% CI, 0.56-1.09), although the estimate … who did not. 51 In another trial, bupropion was associated with abnormal dreams vs placebo, but the estimate … drug use scores not different with nurse home visits vs control Unknown consistency; imprecise estimate … ]) 12 mo: 8.1% vs 8.2% (adjusted OR, 1.13 [95% CI, 0.17-7.44]) Unknown consistency, imprecise estimate … abnormal dreams, muscle pain, and patch-related adverse events than placebo Consistency unknown; estimate
  11. www.uspreventiveservicestaskforce.org/home/getfilebytoken/fbQmoAPKeBekmJ7aqmALe5
    June 01, 2014 - It is difficult to estimate the prevalence of MCI, and estimates range widely, from 3% to 42% in adults … The prevalence of MCI in older adults is difficult to estimate because of differences in the definition … It is difficult to estimate the prevalence of MCI, and estimates range widely, from 3% to 42% in adults … Estimate of Magnitude of Net Benefit The USPSTF found no evidence on the direct benefits and harms of … Overall, the USPSTF was un- able to estimate the balance of benefits and harms of screening for cognitive
  12. www.uspreventiveservicestaskforce.org/home/getfilebytoken/abTWXPvJyAMcqN9KcEt-vt
    September 06, 2016 - The pooled estimate for sensitivity of the QuantiFERON TB Gold IGRA was 0.77 (95% CI, 0.74-0.81; I2 = … Pooled Estimate (95% CI) I2, % No. of Studies Participants, No. … b One study78 could not be included in the DerSimonian-Laird pooled estimate owing to a point estimate … c One study69 could not be included in the pooled estimate owing to a point estimate of 1.0 for sensitivity … The estimate using the maximum likelihood approach, which can accommodate point estimates of 1.0, was
  13. www.uspreventiveservicestaskforce.org/home/getfilebytoken/vTHBrY6VuqjoouJvUmtkr4
    May 01, 2018 - CISNET models use historical SEER data prior to the advent of screening to estimate prostate cancer … The CISNET models estimate the treatment benefit for localized cancer using data from the Scandinavian … Modeling studies subsequently attempted to estimate how much of the observed increase in the incidence … The lowest estimate of the lifetime risk of overdiagnosis (overdiagnosis as a proportion of individuals … To quantify the “intensity” of screening, the modelers estimate what they term “mean restricted lead
  14. www.uspreventiveservicestaskforce.org/home/getfilebytoken/TVsn4SVh_jtaeqSTyrz-Gp
    March 09, 2021 - available evidence and predict long-term outcomes,13-15 the USPSTF commissioned a simulation analysis to estimate … models developed within the Cancer Intervention and Surveillance Modeling Network (CISNET) were used to estimate … Scenario Simulation and Analysis The CISNET simulation models were used to estimate the benefits and … models (Massachusetts General Hospital–Harvard Medical School and University of Michigan) were used to estimate … by Low-Dose Computed Tomography Screenings for the 1960 US Birth Cohort Screening scenarioa Mean estimate
  15. www.uspreventiveservicestaskforce.org/uspstf/recommendation/genital-herpes-serologic-screening
    February 14, 2023 - 6 In 10 studies (n = 6537) using a cut point of 1.1, the HerpeSelect test had a pooled sensitivity estimate … of 99% (95% CI, 97%-100%) and a pooled specificity estimate of 81% (95% CI, 68%-90%), compared with … Western blot. 6 In 4 studies (n = 1512), the Biokit test had a pooled sensitivity estimate of 84% (95% … CI, 73%-91%) and pooled specificity estimate of 95% (95% CI, 93%-97%), compared with Western blot. 6
  16. www.uspreventiveservicestaskforce.org/uspstf/document/evidence-summary/human-immunodeficiency-virus-hiv-infection-screening-2005
    July 05, 2005 - Limitations: Data are insufficient to estimate the effects of screening and interventions on transmission … The other key questions address the chain of evidence necessary to estimate the effects of screening … Evidence was insufficient to estimate the effects of screening on transmission rates. … Is the best available evidence used to estimate effectiveness? Are long-term outcomes used? … Are the best available data used to estimate costs?
  17. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary/osteoporosis-screening
    January 14, 2025 - Two RCTs used 2-stage screening: Fracture Risk Assessment Tool estimate with bone mineral density (BMD … Do we need bone mineral density to estimate osteoporotic fracture risk? … The risk ratio estimate for MOF without SCOOP included is 0.93 (95% CI,  0.86-1.00); absolute effect: … ): AUC, 0.71 (95% CI, 0.60-0.82); sensitivity, 17%; specificity, 96%    Men (1 estimate): sensitivity … (1 estimate): AUC, 0.75 (95% CI, 0.65-0.86); sensitivity, 83%; specificity, 54%    Men (1 estimate):
  18. www.uspreventiveservicestaskforce.org/Home/GetFile/1/16813/prostate-cancer-models-overview/pdf
    May 01, 2018 - CISNET models use historical SEER data prior to the advent of screening to estimate prostate cancer … The CISNET models estimate the treatment benefit for localized cancer using data from the Scandinavian … Modeling studies subsequently attempted to estimate how much of the observed increase in the incidence … The lowest estimate of the lifetime risk of overdiagnosis (overdiagnosis as a proportion of individuals … To quantify the “intensity” of screening, the modelers estimate what they term “mean restricted lead
  19. www.uspreventiveservicestaskforce.org/uspstf/document/final-evidence-summary4/colorectal-cancer-screening-2008
    October 15, 2008 - test and the  I 2  statistic. 34  Because of the stringency of our inclusion criteria for studies to estimate … A random-effects logistic model was used to evaluate statistical heterogeneity, estimate pooled rates … However, existing models can indirectly estimate potential adverse effects for lifetime attributable … Researchers have used CT colonography screening studies already discussed 49 , 53 , 54 to estimate the … We could not estimate complications by age because of limitations in study reporting.
  20. www.uspreventiveservicestaskforce.org/home/getfilebytoken/3qpQqeeozW8nV3a4_BWntp
    June 20, 2019 - Limitations: Data are insufficient to estimate the effects of screening and interventions on transmission … The other key questions address the chain of evi- dence necessary to estimate the effects of screening … Evidence was insufficient to estimate the effects of screening on transmission rates. … Is the best available evidence used to estimate effective- ness? 4. Are long-term outcomes used? … Are the best available data used to estimate costs? Results 1.

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