-
effectivehealthcare.ahrq.gov/sites/default/files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - It makes more sense to estimate the summary sensitivity and specificity and then back-calculate overall
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer-therapy_executive.pdf
May 01, 2013 - Further research is very
unlikely to change our confidence in the estimate of effect. … Further research may
change our confidence in the estimate of effect and may change the estimate. … Further research is likely to
change our confidence in the estimate of effect and is likely to change … the estimate. … The pooled estimate was 0.16 (95% CI, 0.03
to 0.28), a statistically significant result that favored
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-pain-opioid-treatment_executive.pdf
September 19, 2014 - directness of the evidence
linking the intervention and health outcomes; and the
precision of the estimate … linking the intervention and health outcomes (graded
direct or indirect); and the precision of the estimate … that the evidence reflects the true effect and further research
may change our confidence in the estimate … of effect and
may change the estimate. … of effect and is likely to change the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/skin-cancer_research-protocol.pdf
August 10, 2016 - of evidence rating as being
either high, moderate, or low, or there being insufficient evidence to estimate … Incidence Estimate of
Nonmelanoma Skin Cancer
(Keratinocyte Carcinomas) in the US
Population, 2012
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-207-ptsd-disposition-comments.pdf
May 17, 2018 - in study design, conduct, population,
measurements, and analyses suggests that it may be
unwise to estimate … characteristics through stratification or metaregression
may be more informative than a single summary estimate … The pooled
SMD estimate and its 95% CI are shown. … for
estimating the variance component for the random effect
model (for example, DerSimonian & Laird estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gout_executive.pdf
March 01, 2016 - The grades and their definitions are
presented below.11
High: We are very confident that the estimate … i.e., another study would not change
the conclusions
Moderate: We are moderately confident that the estimate … Low: We have limited confidence that the estimate of
effect lies close to the true effect for this outcome … Insufficient: We have no evidence, we are unable to
estimate an effect, or we have no confidence in … the
estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/adhd_executive.pdf
October 01, 2011 - National Survey of Child Health
(NSCH) provides a 2003 estimate of 4.4 million
children who were identified … The estimate of prevalence of ADHD
among adults in the United States is 5.2 percent,8 while
worldwide … linked directly to the health
outcomes)
• Precision (degree of certainty surrounding an
effect estimate … Variability in Prevalence,
Diagnosis, and Treatment
One worldwide pooled prevalence estimate of ADHD … to estimate ADHD prevalence in 2003.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd-update_research-protocol.pdf
August 18, 2016 - • Moderate—We are moderately confident that the estimate of effect lies close to the
true effect … • Low—We have limited confidence that the estimate of effect lies close to the true
effect for this … that additional evidence is needed before concluding either that the
findings are stable or that the estimate … • Insufficient—We have no evidence, we are unable to estimate an effect, or we have
no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/linking-evidence-reviews-methods_0.pdf
October 01, 2018 - The estimates in this table are all from pooled
analyses, except for the estimate for metformin which … comes from DPP, which is still the
best estimate for metformin. … Top study, also
the largest study is the DPP trial, you can see from the pooled estimate (very bottom … And the pooled estimate is 0.65 or 35%
reduction in diabetes (about the same as metformin and smaller … The Phung and colleagues review found a similar point estimate, but their results were
NOT statistically
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/mental-illness-heart_research-protocol.pdf
April 18, 2012 - Further research is
very unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is
likely to change the confidence in the estimate of effect and is likely to change … the
estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/chronic-kidney-disease-anemia-2011_executive.pdf
January 01, 2011 - evidence reflects the
true effect, and that further research is unlikely to change
our confidence in the estimate … the
evidence reflects the true effect, and that further research
may change our confidence in the estimate … , or may change
the estimate. … evidence reflects the true effect, and
that further research is likely to change our confidence in
the estimate … of effect and to change the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/angina-heart-attack-treatments_research-protocol.pdf
December 11, 2012 - Further research is very
unlikely to change our confidence in the estimate of effect.
17
• Moderate—Moderate … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is likely
to change the confidence in the estimate of effect and is likely to change … the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/atrial-fibrillation_research-protocol.pdf
May 22, 2012 - Further research is
very unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is
likely to change the confidence in the estimate of effect and is likely to change … the
estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-tests-bias_methods.pdf
July 01, 2012 - Methods Guide for Medical Test Reviews
5-1
Chapter 5
Assessing Risk of Bias as a Domain of Quality in
Medical Test Studies
P. Lina Santaguida, B.Sc.P.T., Ph.D., M.Sc., McMaster University
Crystal M. Riley, M.A., Nanyang Technological University, Singapore
David B. Matchar, M.D., Duke University;
Duke-…
-
effectivehealthcare.ahrq.gov/sites/default/files/s58.pdf
October 01, 2007 - generally a necessary, but not a sufficient, condition for use/adherence; they
represent an upper-bound estimate … Compare various adherence measures to estimate frequency/types of cases with receipt
but not use. … Validity of a prescription
claims database to estimate medication adherence in older persons.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/breast-biopsy-update_research-protocol.pdf
September 20, 2013 - the evidence as precise or imprecise on the basis of the
degree of certainty surrounding each effect estimate … This certainty is reflected in the confidence interval
of each estimate. … A precise estimate is one that allows for a clinically useful conclusion. … An imprecise
estimate is one for which the confidence interval is wide enough to include clinically
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/juvenile-arthritis-dmards_executive.pdf
September 01, 2011 - Developing a summary estimate of effectiveness of the
DMARDs is challenging because there is:
• Heterogeneity … Some studies
report the percentage improvement from baseline
without providing baseline data or an estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-surgery-preparation_disposition-comments.pdf
April 30, 2014 - Can you make any
estimate of the effect of the antibiotics in those 46 OMBP trials? … We have also
provided power calculations that make direct use
of the event rate information to estimate … for another RCT based
on this meta-analysis, it would be useful for the authors to also
provide an estimate … To test a 20% relative
risk reduction (a more realistic estimate) at a power of 0.9 would
require randomization
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea-diagnosis-future_research.pdf
February 01, 2012 - Using AHI scores of ≥5, ≥10, and ≥15 events/hr to estimate the prevalence of sleep-
disordered breathing … The population-based
studies that aimed to estimate the prevalence of sleep-disordered breathing included … For simplicity, we assume that the goal is
to enroll enough participants to estimate the discriminatory … specificity 83 95 217 73 290 2170
High sensitivity
Low specificity 84 39 207 366 573 2070
* N needed to estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/dementia-databases-methods_research.pdf
May 01, 2008 - Treatment of Dementia Among Community-Dwelling and Institutionalized Medicare Beneficiaries
Effective Health Care
Number 4
Research Reports
Treatment of Dementia Among Community-Dwelling
and Institutionalized Medicare Beneficiaries
Ann L. Gruber-Baldini, Ph.D.
Bruce Stuart, Ph.D.
Ilene Zuckerman, Pharm.D., Ph.D…