-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/chronic-fatigue_research-protocol.pdf
May 01, 2014 - The prevalence of ME/CFS is also difficult to estimate given the uncertainty of the
case definition. … • Moderate — We are moderately confident that the estimate of effect lies close
to the true effect … • Low — We have limited confidence that the estimate of effect lies close to the
true effect for … • Insufficient — We have no evidence, we are unable to estimate an effect, or
we have no confidence … in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/pressure-ulcer-treatment_research-protocol.pdf
November 08, 2011 - applicable)
Directness (direct or indirect)
Precision (precise or imprecise)
We will also estimate … Further research is very
unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is likely
to change the confidence in the estimate of effect and is likely to change … the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/cer-244-safety-vaccines-update-evidence-summary.pdf
May 01, 2021 - Further research is
very unlikely to change our confidence in the estimate of effect. … Further
research may change our confidence in the estimate of effect and may change the
estimate. … Further research is
likely to change our confidence in the estimate of effect and is likely to change … the
estimate … insufficient evidence for rare potential
adverse events for which very large samples would be needed to estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible.pdf
January 01, 2021 - initial study design, we will assign the SOE rating as high,
moderate, low, or insufficient evidence to estimate … High: We are very confident that the estimate of effect lies close to the true effect (i.e.,
the body … Moderate: We are moderately confident that the estimate of effect lies close to the true
effect (i.e … Low: We have limited confidence that the estimate of effect lies close to the true effect
(i.e., the … Insufficient: We have no evidence, are unable to estimate an effect, or have no confidence
in the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/risk-cardiovascular-disease.pdf
January 01, 2023 - initial study design, we will assign the SOE rating as high,
moderate, low, or insufficient evidence to estimate … an effect
High: We are very confident that the estimate of effect lies close to the true effect (i.e … Moderate: We are moderately confident that the estimate of effect lies close to the true
effect (i.e … Low: We have limited confidence that the estimate of effect lies close to the true effect
(i.e., the … Insufficient - We have no evidence, are unable to estimate an effect, or have no confidence
in the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/ch_11-user-guide-to-ocer_130129.pdf
January 03, 2012 - Analyses are available that
can be used to estimate a study result in the presence of an hypothesized … the original analysis to provide quantitative assessment of the robustness (i.e.,
“how much does the estimate … However, violations in assumptions
that result in meaningful effect estimate changes
provide insight … If this check does not influence the
estimate of the association, then it is unlikely that
there is … ‘asa1c’ asa1c 1 -1/ exp;
estimate ‘nsaid1c’ nsaid1c 1 -1/ exp;
estimate ‘cox21c’ cox21c 1 -1/ exp;
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse-drug-therapy_clinician.pdf
February 01, 2016 - Further research is very unlikely to change our confidence in the estimate
of effect. … Further research may change our confidence in the estimate of effect
and may change the estimate. … Further research is likely to change our confidence in the estimate of effect
and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antibiotics-respiratory-infection_clinician.pdf
March 01, 2016 - Further research is very unlikely to change
our confidence in the estimate of effect. … Further research may change
our confidence in the estimate of effect and may
change the estimate. … Further research is likely to change our
confidence in the estimate of effect and is likely to
change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypofractionated-radiation-therapy-protocol.pdf
April 17, 2024 - The four levels are:
• High—Very confident that the estimate of effect lies close to the true effect … • Moderate—Confident that the effect estimate lies close to the true effect for this outcome. … Additional
evidence is needed before concluding that the findings are stable or that the estimate of … Investigators are unable to estimate an effect or have no confidence
in the estimate of the effect of … Precision is the degree of certainty surrounding an effect estimate concerning a given
outcome, based
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/venous-ulcers-treatment_executive.pdf
January 01, 2014 - Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate. … Further research may change our confidence in the estimate of the effect and may change the estimate. … the estimate. … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/peripheral-artery-disease-treatment_executive.pdf
May 01, 2013 - significance of
the effect, which is also reflected by the confidence interval
around the summary estimate … influencing the
significance of the effect (or p-value) include the number
of studies contributing to the estimate … flow diagram
9
of and variation in subgroup analyses precluded the
calculation of any overall estimate … of antiplatelet
therapy for adults with PADa
Comparison Population Outcome SOE
Results or Effect Estimate … Comparative effectiveness and safety of
treatments for ICa
Comparison
Outcome
SOE
Results or Effect Estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/methods-guidance-grading-evidence_methods.pdf
November 01, 2013 - In some
cases, reviewers may be able to conduct a meta-analysis to provide a quantitative estimate of … Score as one of two levels:
• Precise
• Imprecise
A precise estimate is one that would
allow … Judging Precision
When EPCs have conducted a quantitative synthesis and calculated a pooled estimate … estimate of effect for this outcome. … that is more conservative (i.e., closer to the null) than a random effects estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-2-risk-of-reinfection-from-SARSCoV2_0.pdf
December 31, 2022 - This type of
misclassification would be expected to bias the estimate of protection to the null. … This
estimate is formally one minus the relative risk (RR); i.e., protection estimate = 1 – RR. … Leidi, 202138 9 months No variation in protection estimate over
time. … Krutikov, 202130
10 months No variation in the protection estimate
over time. … Methods to estimate the between-study variance
and its uncertainty in meta-analysis.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-abnormalities-tests-update_executive.pdf
February 01, 2012 - When
making medical decisions, a clinician can use likelihood
ratios and test results to estimate the … This estimate is known as a
“pre-test” or “prior” probability. … for the estimate of specificity due to the wide
confidence interval). … The estimate of accuracy was judged to be supported by a
Low strength of evidence. … The estimate of accuracy was judged to
be supported by a low strength of evidence.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/weight-loss-surgery_research-protocol.pdf
December 14, 2010 - For trials that are judged sufficiently clinically similar to warrant meta-analysis, we
will estimate … a pooled random-effects estimate of the overall mean difference in
outcome measure. … Further
research is very unlikely to change our confidence on the estimate of effect. … Further research may change our confidence in the estimate of effect and may
change the estimate. … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-protocol-amendment.pdf
May 02, 2025 - We will use
the restricted maximum likelihood approach to estimate the heterogeneity variance parameter … Lacking such data, we will consider meta-regression to estimate
associations between these factors and … Precision is the degree of certainty surrounding an effect estimate with respect
to a given outcome, … , based
on the width of
confidence intervals
relative to a clinically
important effect
estimate, … , based on
the width of confidence
intervals relative to a
clinically important
effect estimate,
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/ems-blood-transfusion-protocol.pdf
September 24, 2024 - The four levels are:
• High—Very confident that the estimate of effect lies close to the true effect … • Moderate—Confident that the effect estimate lies close to the true effect for this outcome. … Additional
evidence is needed before concluding that the findings are stable or that the estimate of … Investigators are unable to estimate an effect or have no confidence
in the estimate of the effect of … Precision is the degree of certainty surrounding an effect estimate concerning a given
outcome, based
-
effectivehealthcare.ahrq.gov/sites/default/files/s158.pdf
October 01, 2007 - outcome to adjust for unmeasured confound-
ing, propensity score calibration (PSC) leads to a plausible estimate … This multiple im-
putation led to an estimate of the relative risk for lung cancer
and exposure to diesel … Controlling for just age and gender in the
conventional outcome model, we observed a smaller estimate … Thus, adding
information on additional confounders using PSC resulted in
a more plausible estimate for … Flexible matching strategies to increase power
and efficiency to detect and estimate gene-environment
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/celiac-disease_clinician.pdf
July 01, 2016 - Further research is very unlikely to change our confidence in the estimate
of effect. … Further research may change our confidence in the estimate of effect
and may change the estimate. … Further research is likely to change our confidence in the estimate of effect
and is likely to change … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/patient-centered-medical-home_executive.pdf
July 01, 2012 - Further research is very unlikely to change our
confidence in the estimate of effect. … Further research may change our
confidence in the estimate of effect and may change the
estimate. … Further research is likely to change the
confidence in the estimate of effect and is likely to
change … the estimate … The effect size for economic outcomes represents a summary estimate of effect from
meta-analysis.