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effectivehealthcare.ahrq.gov/sites/default/files/nonopioid-chronic-pain-summary.pdf
April 01, 2020 - strength of evidence grades
Strength of Evidence Description
High Very confident that the effect estimate … Moderate Moderately confident that the estimate of effect lies close to the true effect for
this outcome … Low Limited confidence that the effect estimate lies close to the true effect for this
outcome. … Additional
evidence is needed before concluding that the findings are stable or that the
estimate of … Insufficient No confidence in the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/liver-cancer_executive.pdf
October 01, 2014 - We pooled only studies that were clinically comparable and
could provide a meaningful combined estimate … linking
the intervention and health outcomes (graded direct or
indirect); and the precision of the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-265-radiation-bone-disease-addendum-app.xlsx
May 29, 2025 - Title
Addendum Appendix - Evidence Table
Table1. Evidence Table Addendum
Table 1. Evidence table for a randomized controlled trial evaluating external beam radiation therapy for the palliative treatment of metastatic bone disease identified after submission of final report and summarized in …
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effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/alcohol-pharma-final-protocol.pdf
January 01, 2023 - the data qualitatively.
16
For quantitative syntheses, we will use random-effects models to estimate … Further research is very
unlikely to change our confidence in the estimate of effect. … Further research may
change our confidence in the estimate of the effect and may change the estimate … Further research is likely to
change our confidence in the estimate of the effect and is likely to change … the
estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/hemorrhage-postpartum_executive.pdf
April 01, 2015 - Further research may change our
confidence in the estimate of effect and may change the
estimate. … Further research is likely to change confidence
in the estimate of effect and is also likely to change … the
estimate
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-205-predictors-trauma-care-evidence-summary.pdf
April 01, 2018 - We
also pooled data to estimate sensitivity and specificity
results for blood pressure and lactate … amenable to
pooling as they use different thresholds and outcomes,
and the differences across our pooled estimate
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/version-3-immunity-after-COVID-19.pdf
December 31, 2022 - variant or the wild-type SARS-CoV-2
virus reduced the risk of another infection by 80–97 percent (pooled estimate … None of the controlled studies we reviewed,
including those we excluded, provided a useful estimate … that compared vaccinated individuals to previous infection
alone if they did not provide a protection estimate … variation in the four areas did not account
for the variation in our protection against reinfection estimate
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/cer-218-osteoporosis-disposition-comments.pdf
April 23, 2019 - from which the fracture reduction and
AFF and ONJ risk estimates were derived, we elected
to not estimate … However, there are numerous instances when 95% CI
around the HR point estimate was so broad that nothing … no consensus about what should
tip the scale between no confidence and limited
confidence in the estimate … Zillikens (CTI 2018), we added the following
recommendations for future research: (1) to better
estimate
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - ve clarified
that the degree of certainty part is related to the
magnitude of effect of the effect estimate … adequate, we further assessed
precision based on the magnitude of the effects
represented by the effect estimate … Peer Reviewer 9 Results Figure 25: two studies, the combined estimate has
wider CrI than the individual … If a Bayesian random
effects model was used, there is a direct estimate of
heterogeneity automatically
-
effectivehealthcare.ahrq.gov/sites/default/files/antipsychotics-children-update-disposition-170621.pdf
March 16, 2017 - ve clarified
that the degree of certainty part is related to the
magnitude of effect of the effect estimate … adequate, we further assessed
precision based on the magnitude of the effects
represented by the effect estimate … Peer Reviewer 9 Results Figure 25: two studies, the combined estimate has
wider CrI than the individual … If a Bayesian random
effects model was used, there is a direct estimate of
heterogeneity automatically
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/head-neck-cancer_executive.pdf
May 01, 2010 - Layout 1
Background
Head and neck cancers, specifically those
arising in the oral cavity, larynx,
hypopharynx, oropharynx, nasopharynx,
paranasal sinuses/nasal cavity, salivary
glands, and occult primaries, account for
approximately 3 to 5 percent of cancers in
the United States. According to the
National Comprehens…
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effectivehealthcare.ahrq.gov/sites/default/files/wysiwyg/white-paper-standardized-library.pdf
February 01, 2019 - ClinicalTrials.gov
Most of the studies are fairly
small, however 2 are really large:
17 studies estimate … that they will
have between 24 – 1,000
enrollees; 6 estimate between
1,000 – 12,000; 3 estimate … between 12,001 – 50,000; 2
estimate having 500,000 enrollees
4 of the studies are funded by
industry
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/public-reporting-quality-improvement_executive.pdf
July 01, 2012 - the evidence reflects the true effect;
further research is unlikely to change our confidence or
the estimate … confidence
that the evidence reflects the true effect; further research
may change our confidence or the estimate … the evidence reflects the true
effect; further research is likely to change our confidence
and the estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/adhd_research-protocol.pdf
August 10, 2010 - Fewer
attempts have been made to estimate prevalence among adults. … linked directly to the health outcomes)
5) Precision (degree of certainty surrounding an effect estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/progestogens-preterm-birth_research-protocol.pdf
June 01, 2010 - regimen is relatively modest; one study estimates it to be about $400 per treated
patient.10 This estimate
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effectivehealthcare.ahrq.gov/sites/default/files/related_files/breast-cancer-medications_appendixes.pdf
March 01, 2009 - Graphs to estimate an individualized risk of breast
cancer. J Clin Oncol 1996;14(1):103-110. … is an estimate that
would allow a clinically useful conclusion.. … Further research is very unlikely to
change our confidence in the estimate of effect. … Further research may
change our confidence in the estimate of effect
and may change the estimate. … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/colorectal-cancer-screening_disposition-comments.pdf
February 01, 2012 - state that: …very low sensitivities were reported for FOBT
which are not consistent with previous estimate … A case-control study would not be valid to estimate specificity per
se, since subjects with small or … We have confirmed this calculation with our
statistician and agree that this is a valid way to
estimate … cases, the authors should discuss the extent to which appropriate
case-control studies may be used to estimate … already addresses the problems of initial
validation studies, and that they are not
sufficient to estimate
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/depression-childhood-protocol.pdf
August 06, 2018 - One nationally representative estimate indicated that
about 1 in 12 (8-9 %) adolescents ages 13 to 17 … For all analyses, we will use random
effects models to estimate pooled or comparative effects; unlike … Further research is very unlikely
to change our confidence in the estimate of effect. … Further research may change
our confidence in the estimate of the effect and may change the estimate … the estimate.
-
effectivehealthcare.ahrq.gov/sites/default/files/pdf/antipsychotics-children-update_research-protocol.pdf
December 04, 2015 - High We are very confident that the estimate of effect lies close to the true
effect for this outcome … Moderate We are moderately confident that the estimate of effect lies close to the
true effect for … Low We have limited confidence that the estimate of effect lies close to the
true effect for this outcome … Insufficient We have no evidence, we are unable to estimate an effect, or we have
no confidence in … the estimate of effect for this outcome.
-
effectivehealthcare.ahrq.gov/sites/default/files/related_files/medical-test-reviews-meta-analysis.ppt
June 01, 2012 - It makes more sense to estimate the summary sensitivity and specificity and then back-calculate overall