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Showing results for "estimate".

401. Case Study Comparing Bayesian and Frequentist Approaches for Multiple Treatment Comparisons (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/indirect-comparisons_research.pdf
     March 01, 2013 - That is, to estimate a relative effect of two treatments, using a log odds ratio of the magnitude … We first fit a purely fixed effects model that further assumes all studies estimate the same effect … We can estimate Σ by likelihood based methods provided the data contain at least some information on … Patients may 12 have differential sensitivity to specific adverse events, but to estimate this … Using mixed treatment comparisons and meta- regression to perform indirect comparisons to estimate

402. Disposition of Comments for Pulmonary Arterial Hypertension: Screening, Management, and Treatment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertension-pulmonary-arterial_disposition-comments.pdf
     April 25, 2013 - In the studies we evaluated, we attempted to estimate the proportion of patients who failed to have … In the studies we evaluated, we attempted to estimate the proportion of patients who failed to have … Second, there is convention in echocardiography to estimate left sided filling pressures - this is … In the studies we evaluated, we attempted to estimate the proportion of patients who failed to have … The revised report includes a sufficient number of studies to generate a summary estimate for change

403. Smoking-Pregnancy-Infants Research-Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/smoking-pregnancy-infants_research-protocol.pdf
     March 11, 2013 - This analytic approach will allow both an estimate of the overall (population) effect, as well as an … estimate of the variance of the effect across studies. … that the evidence reflects the true effect and further research may change our confidence in the estimate … of effect and may change the estimate), “low” (indicating low confidence that the evidence reflects … of effect and is likely to change the estimate), or “insufficient” (indicating that evidence is either

404. Dietary-Supplements Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/dietary-supplements_executive.pdf
     April 01, 2012 - evidence from the contributing study/studies was underpowered for the outcome of interest (imprecise estimate … When an effect estimate was associated with a confidence interval (CI) that was not only nonsignificant … Outcome results were considered to be inconclusive when the pooled estimate or the single contributing … study estimate had confidence intervals wide enough to incorporate both clinically important benefit … Question 2 (continued) Outcome Dietary Supplement + Cardiovascular Drug(s) Conclusion, Effect Estimate

405. Guidance for the Conduct and Reporting of Modeling and Simulation Studies in the Context of Health Technology Assessment (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/decision-models-guidance_methods.pdf
     October 01, 2016 - they believe to be wrong and then qualify it—for example, “We think the estimate may be high because … This approach makes it difficult to justify putting out a numerical estimate. Box 1. … Example Explicit adjustment for bias means that the pooled effect size estimate would take … into account concerns about quality and be interpretable as the authors’ best estimate of the effect … Adjusting a relative-risk estimate for study imperfections.

406. Attention Deficit Hyperactivity Disorder: Diagnosis and Treatment in Children and Adolescents - Systematic Review Protocol (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/product/pdf/deficit-hyperactivity-protocol.pdf
     November 01, 2021 - • Imprecision: Describes the level of certainty of the estimate of effect for a particular outcome … , where a precise estimate is one that allows a clinically useful conclusion. … • Low: We have limited confidence that the estimate of effect lies close to the true effect for this … • Insufficient: We have no evidence, we are unable to estimate an effect, or we have no confidence … in the estimate of effect for this outcome.

407. Disposition of Comments_Comparative Effectiveness Review No. 263: Management of Postpartum Hypertensive Disorders of Pregnancy (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/hypertensive-disorders-pregnancy-disposition-comments.pdf
     May 31, 2023 - In section 3.3.4.1, we estimate a seizure risk of 9 per 1000 patients with preeclampsia with severe … The point estimate for the comparative odds of seizure is 0.72 (lower odds with shorter-duration regimens … However, this estimate is imprecise (hence insufficient for a graded conclusion) and the confidence

408. Hepatic-Fibrosis White-Paper (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/hepatic-fibrosis_white-paper.pdf
     April 01, 2014 - of >=0.20 or >0.26 was re-classified from less useful to moderately useful, but the impact on the estimate … with a cutoff of >1.0 were reclassified from less useful to moderately useful, but the impact on the estimate … predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate … predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate

409. Disposition of Comments_Technical Brief No. 44: Measuring Primary Healthcare Spending (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/primary-healthcare-spending-disposition-comments.pdf
     May 17, 2024 - authors to briefly add mention in the text in this section of this approach to using dummy claims to estimate … tends to fall towards the higher range of state PC spend estimates, about how much of this higher estimate … smaller denominator, then this decision alone would result in an approximately 25% lower PC spend estimate … addressed the need for conducting research to identify the elements of primary care spending estimate

410. Future Research Needs for Childhood Obesity Prevention Programs (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/pdf/child-obesity-future_research.pdf
     March 31, 2010 - Future Research Needs for Childhood Obesity Prevention Programs Future Research Needs Paper Number 31 Future Research Needs for Childhood Obesity Prevention Programs Future Research Needs Paper Number 31 Future Research Needs for Childhood Obesity Prevention Programs Identification of Future Resea…

411. Executive Summary_Systematic Review: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/effect-dietary-digestible-executive-summary.pdf
     March 01, 2025 - Executive Summary_Systematic Review: Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition Systematic Review Association of Digestible Carbohydrate Intake With Cardiovascular Disease, Type 2 Diabetes, Obesity, and Body Composition Execu…

412. Improving the Management of Menopausal Symptoms in Perimenopausal and Early Postmenopausal Women: A Systematic Review (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/menopausal-symptoms-protocol.pdf
     October 15, 2024 - Moderate We are moderately confident that the estimate of effect lies close to the true effect for this … Low We have limited confidence that the estimate of effect lies close to the true effect for this outcome … that additional evidence is needed before concluding either that the findings are stable or that the estimate … Insufficient We have no evidence, we are unable to estimate an effect, or we have no confidence in the … estimate of effect for this outcome.

413. App-E-Surv-Report-3-Acute-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-3-acute-pain.xlsx
     May 29, 2025 - E-1. KQ1 RCTs Table E-1. Key Question 1: Acute back pain treatment trials Author, Year (Appendix C Has Full Citations of Included Studies) Setting Country Specific Pain Condition Radiculopathy Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized N Anal…

414. App-E-Surv-Report-2-Acute-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-report-2-acute-pain.xlsx
     May 29, 2025 - E-1. KQ1 RCTs Table E-1. Key Question 1: Acute back pain treatment trials Author, Year (Appendix C Has Full Citations of Included Studies) Setting Country Specific Pain Condition Radiculopathy Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized N Anal…

415. App-E-Surv-Rept-1-Acute-Pain (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/app-e-surv-rept-1-acute-pain.xlsx
     May 29, 2025 - E-1. KQ1 RCTs Table E-1. Key Question 1: Acute back pain treatment trials Author, Year (Appendix C Has Full Citations of Included Studies) Setting Country Specific Pain Condition Radiculopathy Intervention Types Compared Intervention Names and Doses Intervention Dose in Daily Morphine Equivalent N Randomized N Anal…

416. Disposition of Comments_Comparative Effectiveness Review No. 276: Diagnosis and Managment of Obsessive Compulsive Disorders in Children (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/obsessive-compulsive-disorder-disposition-comments.pdf
     December 06, 2024 - intervention approaches, we display individual study effects for these 3 studies, but do not report a summary estimate

417. Bladder-Cancer-Non-Muscle-Invasive Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/bladder-cancer-non-muscle-invasive_executive.pdf
     October 01, 2015 - reflects the true effect and that further research is very unlikely to change our confidence in the estimate … of effect and may change the estimate. … the evidence reflects the true effect; further research is likely to change the confidence in the estimate … of effect and is likely to change the estimate. … bladder cancer and thereby reduce the need for cystoscopy depends on the ability of clinicians to estimate

418. Gastric-Cancers-Supplementary-App-E (xls file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/gastric-cancers-supplementary-app-e.xlsx
     June 25, 2025 - E-1. OS LT Table E-1. Overall survival league table Pre-op Fluoro+Plat+Taxane + Post-op Fluoro . . . . . . 0.76 [0.55; 1.05] . . . . . . . . . 1.03 [0.51; 2.09] Periop Fluoro+Plat+Taxane+Antiangio 0.92 [0.55; 1.53] . . . . . . . . . . . . . . 0.95 [0.58; 1.55] 0.92 [0.55; 1.53] Periop Fluoro+Plat+Taxane . 1.05 [0.5…

419. Disposition of Comments for Use of Natriuretic Peptide Measurement in the Management of Heart Failure (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/heart-failure-natriuretic-peptide_disposition-comments.pdf
     November 20, 2013 - Further, studies with the smallest CI will have more weight in a pooled estimate. … the Porapakkham’s study found that removal of the TIME study (contributing 49.6% weight) gave an estimate … In our judgment the clinical heterogeneity precluded summary estimate computations. … We presented the data present in the publications and did not attempt to estimate which was not present … Section Comment Response Rev 8 ES ES-9: very detailed section about the effect of age on accuracy estimate

420. Tinnitus Executive (pdf file)
     effectivehealthcare.ahrq.gov/sites/default/files/related_files/tinnitus_executive.pdf
     August 01, 2013 - 1 Comparative Effectiveness Review Number 122 Evaluation and Treatment of Tinnitus: Comparative Effectiveness Executive Summary Background Tinnitus is the perception of sound in the absence of an external auditory stimulus; as such, tinnitus is a symptom, not a disease. An estimated 16 percent of the America…