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  1. effectivehealthcare.ahrq.gov/sites/default/files/pdf/sleep-apnea_research-protocol.pdf
    March 15, 2010 - precision (precise or imprecise) of the evidence based on the degree of certainty surrounding an effect estimate … A precise estimate is an estimate that would allow a clinically useful conclusion. … An imprecise estimate is one for which the confidence interval is wide enough to include clinically
  2. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ace-inhibitor-arb-2007_research-2007-1.pdf
    January 01, 2007 - of effect and may change the estimate. … of effect and is likely to change the estimate. … Very low – Any estimate of effect is very uncertain. … The latter estimate is likely to be more clinically relevant. Figure 5. … The latter estimate is likely to be more clinically relevant.
  3. effectivehealthcare.ahrq.gov/sites/default/files/pdf/mgmt-hnhc-patients-protocol.pdf
    November 07, 2019 - For all analyses, we will use random effects models to estimate pooled or comparative effects; unlike … Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of the effect and may change the estimate … Further research is likely to change our confidence in the estimate of the effect and is likely to … change the estimate.
  4. Untitled (pdf file)

    effectivehealthcare.ahrq.gov/sites/default/files/pdf/aggression_research-protocol.pdf
    October 05, 2015 - estimate!of!effect!lies!close!to!the!true!effect!for!this!outcome.! The!body!of!evidence!has!few! … estimate!of!effect!lies!close!to!the!true!effect!for!this! outcome.!The!body!of!evidence!has!some! … estimate!of!effect!lies!close!to!the!true!effect!for!this! outcome.!The!body!of!evidence!has!major! … estimate!of!effect!is!close!to!the!true!effect.!! Insufficient! We!have!no!evidence,!we!are! … estimate!an!effect,!or!we!have!no!confidence!in!the! estimate!of!effect!for!this!outcome.!No!
  5. effectivehealthcare.ahrq.gov/sites/default/files/related_files/infantile-hemangioma_disposition-comments.pdf
    January 15, 2016 - But there is no evidence that this underlying distribution is used to generate an overall estimate … uncertainty is much higher in the RCT-only model, due to reduced number of studies, and the point estimate … Timolol moved, but there is almost no information about Timolol without cohort studies, so the point estimate … variable model formulation, which allows arbitrary cutoff values from each study that are combined to estimate … estimates a combined probability for each arm, which is not the model used in the meta-analysis to estimate
  6. effectivehealthcare.ahrq.gov/sites/default/files/related_files/atrial-fibrillation_executive.pdf
    June 01, 2013 - Summary of strength of evidence and effect estimate for KQ 2 Outcome Strength of Evidence and Effect … Summary of strength of evidence and effect estimate for KQ 3—one rate-control procedure versus another … Summary of strength of evidence and effect estimate for KQ 4 Treatment Comparison Restoration of Sinus … Summary of strength of evidence and effect estimate for KQ 6—rate- versus rhythm- control strategies … Outcome Strength of Evidence and Effect Estimate Maintenance of sinus rhythm Using AADs for rhythm
  7. effectivehealthcare.ahrq.gov/sites/default/files/pdf/hip-fracture-pain_clinician.pdf
    May 01, 2011 - For all modalities, the evidence is generally inadequate to estimate harms and the incidence of adverse
  8. effectivehealthcare.ahrq.gov/sites/default/files/pdf/observational-research-scores_research.pdf
    May 01, 2012 - Confounding ................................................................................... 5 Build/Estimate … Build/Estimate Propensity Score Comparison Group Once the decision to use propensity scores in study … (or “calibrated”) propensity score is then applied to the original population providing an effect estimate … increased cardiovascular risk, variable selection procedures may be considered to improve exposure estimate … This is then used to fit a model in the unexposed group from which one can estimate the probability
  9. effectivehealthcare.ahrq.gov/sites/default/files/related_files/osteoporosis-bone-fracture_executive.pdf
    March 01, 2012 - point in his lifetime.3 The economic burden of osteoporosis is large and growing: the most recent estimate … Further research is very unlikely to change our confidence on the estimate of effect. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change our confidence in the estimate of effect and is likely to change … the estimate.
  10. effectivehealthcare.ahrq.gov/sites/default/files/related_files/diabetes-behavior-programs_disposition-comments.pdf
    September 28, 2015 - the EPC guidance recommends sensitivity analyses using both change score and follow up score to estimate … the mean SD from the pooled studies which has been shown to represent a universal, conservative estimate … While Hartung- Knapp-Sidik-Jonkman estimate is shown to result in more adequate error rates than the … For example, Figure 8, adults results, the 95% CI for the combined estimate is much wider than the … 95% CI for each included estimate while I2 = 0%.
  11. effectivehealthcare.ahrq.gov/sites/default/files/related_files/pressure-ulcer-treatment_executive.pdf
    May 01, 2013 - Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of effect and may change the estimate. … Further research is likely to change the confidence in the estimate of effect and is likely to change … the estimate … However, variability across studies precluded an estimate of adverse events for specific dressings
  12. effectivehealthcare.ahrq.gov/sites/default/files/ch_3-user-guide-to-ocer_130129.pdf
    September 21, 2012 - Despite the presence of this heterogeneity, many studies estimate an average treatment effect (ATE) … The main goals of HTE analysis are to estimate treatment effects in clinically relevant subgroups and … Goals of HTE Analysis There are two main goals of HTE analyses: (1) to estimate treatment effects in
  13. effectivehealthcare.ahrq.gov/sites/default/files/pdf/atypical-antipsychotics-seniors-death_research.pdf
    August 01, 2007 - Linear regression to estimate risk difference is valid in large samples like ours.32 Because patient-level … conventional agent, haloperidol, increased the risk of short- term mortality vs. placebo by 107% —an estimate
  14. effectivehealthcare.ahrq.gov/sites/default/files/related_files/dementia-nursing-home-characteristics_executive.pdf
    October 01, 2012 - Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of the effect and may change the estimate … Further research is likely to change our confidence in the estimate of the effect and is likely to … change the estimate.
  15. effectivehealthcare.ahrq.gov/sites/default/files/pdf/nephropathy-contrast-induced_research-protocol.pdf
    October 01, 2013 - CI for I2 statistic should also be provided, whenever possible, to reflect the uncertainty in the estimate … evidence reflects the true effect and further research is very unlikely to change our confidence in the estimate … that the evidence reflects the true effect, and further research may change our confidence in the estimate … evidence reflects the true effect and further research is likely to change our confidence in the estimate … of the effect and is likely to change the effect estimate); and insufficient grade (evidence is unavailable
  16. effectivehealthcare.ahrq.gov/sites/default/files/pdf/ear-infection_research-protocol.pdf
    August 07, 2012 - evidence reflects the true effect: Further research is very unlikely to change our confidence in the estimate … confidence that the evidence reflects the true effect: Further research may change our confidence in the estimate … of the effect and may change the estimate. … the evidence reflects the true effect: Further research is likely to change our confidence in the estimate … of the effect and is likely to change the estimate.
  17. effectivehealthcare.ahrq.gov/sites/default/files/pdf/wireless-motility-capsule_research-protocol.pdf
    March 14, 2012 - reflects the true effect and that further research is very unlikely to change our confidence in the estimate … that the evidence reflects the true effect and that further research may change our confidence in the estimate … www.effectivehealthcare.ahrq.gov/ Source: www.effectivehealthcare.ahrq.gov Published Online: March 14, 2012 the estimate … evidence reflects the true effect and that further research is likely to change our confidence in the estimate … of the effect and is likely to change the estimate); and 4) “insufficient strength of evidence (evidence
  18. effectivehealthcare.ahrq.gov/sites/default/files/pdf/alcohol-misuse_research-protocol.pdf
    April 28, 2010 - Further research is very unlikely to change our confidence in the estimate of effect. … Further research may change our confidence in the estimate of the effect and may change the estimate … Further research is likely to change our confidence in the estimate of the effect and is likely to … change the estimate.
  19. effectivehealthcare.ahrq.gov/sites/default/files/pdf/colorectal-surgery-preparation_research-protocol.pdf
    March 26, 2013 - This cutoff is chosen to ensure that studies can estimate low event rates with adequate precision.b … appropriate, quantitatively) to better evaluate (and if statistical analyses are deemed appropriate, to estimate … the evidence as precise or imprecise on the basis of the degree of certainty surrounding each effect estimate … A precise estimate is one that allows for a clinically useful conclusion. … An imprecise estimate is one for which the confidence interval is wide enough to include clinically
  20. effectivehealthcare.ahrq.gov/sites/default/files/related_files/grading-quiz.ppt
    May 29, 2025 - , whether the evidence base has head-to-head studies), and precision (i.e., degree of certainty for estimate

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